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Encephalocele
Encephalocele is a neural tube defect characterized by sac-like protrusions of the brain and the Biological membrane, membranes that cover it through openings in the human skull, skull. These defects are caused by failure of the neural tube to close completely during fetal development. Encephaloceles cause a groove down the middle of the skull, or between the forehead and nose, or on the back side of the skull. The severity of encephalocele varies, depending on its location. Signs and symptoms Encephaloceles are often accompanied by craniofacial abnormalities or other brain malformations. Symptoms may include neurologic problems, hydrocephalus (cerebrospinal fluid accumulated in the brain), spastic quadriplegia (paralysis of the limbs), microcephaly (an abnormally small head), ataxia (uncoordinated muscle movement), developmental delay, vision problems, mental and growth retardation, and seizures. File:Encephalocele of a newborn.JPG, A neonate with a large encephalocele. File:En ...
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Neural Tube Defect
Neural tube defects (NTDs) are a group of birth defects in which an opening in the spine or cranium remains from early in human development. In the third week of pregnancy called gastrulation, specialized cells on the dorsal side of the embryo begin to change shape and form the neural tube. When the neural tube does not close completely, an NTD develops. Specific types include: spina bifida which affects the spine, anencephaly which results in little to no brain, encephalocele which affects the skull, and iniencephaly which results in severe neck problems. NTDs are one of the most common birth defects, affecting over 300,000 births each year worldwide. For example, spina bifida affects approximately 1,500 births annually in the United States, or about 3.5 in every 10,000 (0.035% of US births), which has decreased from around 5 per 10,000 (0.05% of US births) since folate fortification of grain products was started. The number of deaths in the US each year due to neural tu ...
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Spina Bifida
Spina bifida (SB; ; Latin for 'split spine') is a birth defect in which there is incomplete closing of the vertebral column, spine and the meninges, membranes around the spinal cord during embryonic development, early development in pregnancy. There are three main types: spina bifida occulta, meningocele and myelomeningocele. Meningocele and myelomeningocele may be grouped as spina bifida cystica. The most common location is the Lumbar vertebrae, lower back, but in rare cases it may be in the Thoracic vertebrae, middle back or Cervical vertebrae, neck. Occulta has no or only mild signs, which may include a hairy patch, dimple, dark spot or swelling on the back at the site of the gap in the spine. Meningocele typically causes mild problems, with a sac of fluid present at the gap in the spine. Myelomeningocele, also known as open spina bifida, is the most severe form. Problems associated with this form include poor ability to walk, impaired Neurogenic bladder dysfunction, bladder o ...
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Meningocele
Spina bifida (SB; ; Latin for 'split spine') is a birth defect in which there is incomplete closing of the spine and the membranes around the spinal cord during early development in pregnancy. There are three main types: spina bifida occulta, meningocele and myelomeningocele. Meningocele and myelomeningocele may be grouped as spina bifida cystica. The most common location is the lower back, but in rare cases it may be in the middle back or neck. Occulta has no or only mild signs, which may include a hairy patch, dimple, dark spot or swelling on the back at the site of the gap in the spine. Meningocele typically causes mild problems, with a sac of fluid present at the gap in the spine. Myelomeningocele, also known as open spina bifida, is the most severe form. Problems associated with this form include poor ability to walk, impaired bladder or bowel control, accumulation of fluid in the brain, a tethered spinal cord and latex allergy. Some experts believe such an allergy ca ...
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Developmental Delays
Global developmental delay is an umbrella term used when children are significantly delayed in two or more areas of development. It can be diagnosed when a child is delayed in one or more milestones, categorised into motor skills, speech, cognitive skills, and social and emotional development. There is usually a specific condition which causes this delay, such as cerebral palsy, Fragile X syndrome or other chromosomal abnormalities. However, it is sometimes difficult to identify this underlying condition. Other terms associated with this condition are failure to thrive (which focuses on lack of weight gain and physical development), intellectual disability (which focuses on intellectual deficits and the changes they cause to development) and developmental disability (which can refer to both intellectual and physical disability altering development). Causes Developmental delay can be caused by learning disabilities, in which case the delay can usually be overcome with time and suppo ...
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Discovery Channel
Discovery Channel, known as The Discovery Channel from 1985 to 1995, and often referred to as simply Discovery, is an American cable channel that is best known for its ongoing reality television shows and promotion of pseudoscience. It initially provided documentary television programming focused primarily on popular science, technology, and history, but by the 2010s had become increasingly dominated by programs that were reality television shows, promoted conspiracy theories, or advocated junk science. It is owned by Warner Bros. Discovery, a publicly traded company run by CEO David Zaslav. , Discovery Channel was the third most widely distributed subscription channel in the United States, behind now-sibling channel TBS and the Weather Channel; it is available in 409 million households worldwide, through its U.S. flagship channel and its various owned or licensed television channels internationally. , Discovery Channel is available to approximately 71,000,000 pa ...
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Operation Smile
Operation Smile is a nonprofit medical service organization founded in 1982 by husband and wife William P. Magee Jr. and Kathleen (Kathy) S. Magee. It is headquartered in Virginia Beach, Virginia. In addition to providing cleft lip and palate repair surgeries to children worldwide, Operation Smile works as a non-governmental organization to reduce the occurrence of cleft lips and palates worldwide. Operation Smile has provided over 350,000 surgeries for children and young adults born with cleft lips, cleft palates, and other facial deformities in over 60 countries since 1982, at no cost to the recipients. As of 2022, Operation Smile provided on-going care around the world at 38 smile centers. Early history Operation Smile was founded by William (Bill) and Kathleen (Kathy) Magee. In 1982 Bill Magee, a plastic surgeon, and Kathy Magee, who was then a social worker and a nurse, were invited to join a Philippine cleft repair mission with a group of medical volunteers. When they ...
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The Facemakers
''The'' is a grammatical article in English, denoting nouns that are already or about to be mentioned, under discussion, implied or otherwise presumed familiar to listeners, readers, or speakers. It is the definite article in English. ''The'' is the most frequently used word in the English language; studies and analyses of texts have found it to account for seven percent of all printed English-language words. It is derived from gendered articles in Old English which combined in Middle English and now has a single form used with nouns of any gender. The word can be used with both singular and plural nouns, and with a noun that starts with any letter. This is different from many other languages, which have different forms of the definite article for different genders or numbers. Pronunciation In most dialects, "the" is pronounced as (with the voiced dental fricative followed by a schwa) when followed by a consonant sound, and as (homophone of the archaic pronoun ''thee'' ...
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Neurology
Neurology (from , "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine) , medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous system, which comprises the Human brain, brain, the spinal cord and the peripheral nervous system , peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system, using various techniques of neurotherapy. IEEE Brain (2019). "Neurotherapy: Treating Disorders by Retraining the Brain". ''The Future Neural Therapeutics White Paper''. Retrieved 23.01.2025 from: https://brain.ieee.org/topics/neurotherapy-treating-disorders-by-retraining-the-brain/#:~:text=Neurotherapy%20trains%20a%20patient's%20brain,wave%20activity%20through%20positive%20reinforcement International Neuromodulation Society, Retrieved 23 January 2025 from: https://www.neuromodulation.com/ Val Danilov I (2023). "The O ...
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Nasal Placode
In embryology, the nasal placode (or olfactory placode) gives rise to the olfactory epithelium of the human nose, nose. Two nasal Neurogenic placode, placodes arise as thickened ectoderm from the frontonasal process. They give rise to the human nose, nose, the philtrum of the upper lip, and the primary palate. Development During the fifth week of human embryonic development, the placodes increase in size. In the sixth week of development the centre of each placode invagination, grows inwards to form the two nasal pits. The invaginations will give rise to the olfactory epithelium that lines the roof of the nasal cavity. The nasal pits are oval shaped and they leave a raised margin which is divided into a medial nasal process and a lateral nasal process. The medial and lateral nasal process of each placode gives rise to the nose, the philtrum of the upper lip and the primary palate. References External links

* https://web.archive.org/web/20130509194720/http://embryology.me ...
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Cribiform Plate
In mammalian anatomy, the cribriform plate (Latin for lit. ''sieve-shaped''), horizontal lamina or lamina cribrosa is part of the ethmoid bone. It is received into the ethmoidal notch of the frontal bone and roofs in the nasal cavities. It supports the olfactory bulb, and is perforated by olfactory foramina for the passage of the olfactory nerves to the roof of the nasal cavity to convey smell to the brain. The foramina at the medial part of the groove allow the passage of the nerves to the upper part of the nasal septum while the foramina at the lateral part transmit the nerves to the superior nasal concha. A fractured cribriform plate can result in olfactory dysfunction, septal hematoma, cerebrospinal fluid rhinorrhoea (CSF rhinorrhoea), and possibly infection which can lead to meningitis. CSF rhinorrhoea (clear fluid leaking from the nose) is very serious and considered a medical emergency. Aging can cause the openings in the cribriform plate to close, pinching olfactory ne ...
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Desiccation
Desiccation is the state of extreme dryness, or the process of extreme drying. A desiccant is a hygroscopic (attracts and holds water) substance that induces or sustains such a state in its local vicinity in a moderately sealed container. The word desiccation comes . Industry Desiccation is widely employed in the oil and gas industry. These materials are obtained in a hydrated state, but the water content leads to corrosion or is incompatible with downstream processing. Removal of water is achieved by cryogenics, cryogenic condensation, absorption into glycols, and absorption onto desiccants such as silica gel. Laboratory A desiccator is a heavy glass or plastic container, now somewhat antiquated, used in practical chemistry for drying or keeping small amounts of materials very dry. The material is placed on a shelf, and a drying agent or ''desiccant'', such as dry silica gel or anhydrous sodium hydroxide, is placed below the shelf. Often some sort of humidity indicator is ...
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