Emil Palade
George Emil Palade (; November 19, 1912 – October 7, 2008) was a Romanian-American cell biology, cell biologist.Archived (Internet Archive copy) In 1974 he was awarded the Nobel Prize in Physiology or Medicine along with Albert Claude and Christian de Duve. The prize was granted for his innovations in electron microscopy and cell fractionation which together laid the foundations of modern molecular cell biology, the most notable discovery being the ribosomes of the endoplasmic reticulum – which he first described in 1955. Palade also received the U.S. National Medal of Science in Biological Sciences for "pioneering discoveries of a host of fundamental, highly organized structures in living cells" in 1986, and was previously elected a Member of the U.S. N ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Iași
Iași ( , , ; also known by other #Etymology and names, alternative names), also referred to mostly historically as Jassy ( , ), is the Cities in Romania, third largest city in Romania and the seat of Iași County. Located in the historical region of Western Moldavia, Moldavia, it has traditionally been one of the leading centres of Romanian social, cultural, academic and artistic life. The city was the capital of the Principality of Moldavia from 1564 to 1859, then of the United Principalities from 1859 to 1862, and the capital of Kingdom of Romania, Romania from 1916 to 1918. Known as the Cultural Capital of Romania Iași is a symbol of Romanian history. Historian Nicolae Iorga stated that "there should be no Romanian who does not know of it". Still referred to as "The Moldavian Capital", Iași is the main economic and business centre of Romania's Moldavian region. In December 2018, Iași was officially declared the Historical Capital of Romania. At the 2021 Romanian censu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by Charles II of England, King Charles II and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the society's president, according to a set of statutes and standing orders. The members of Council and the president are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cell Fractionation
In cell biology, cell fractionation is the process used to separate cell organelle, cellular components while preserving individual functions of each component. This is a method that was originally used to demonstrate the cellular location of various biochemical processes. Other uses of subcellular fractionation is to provide an enriched source of a protein for further purification, and facilitate the diagnosis of various disease states. Homogenization Tissue is typically tissue homogenization, homogenized in a buffer solution that is Isotonicity, isotonic to stop osmotic damage. Mechanisms for homogenization include grinding, mincing, chopping, pressure changes, osmotic shock, freeze-thawing, and ultrasound. The samples are then kept cold to prevent enzymatic damage. It is the formation of homogenous mass of cells (cell homogenate or cell suspension). It involves grinding of cells in a suitable medium in the presence of certain enzymes with correct pH, ionic composition, and te ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Electron Microscopy
An electron microscope is a microscope that uses a beam of electrons as a source of illumination. It uses electron optics that are analogous to the glass lenses of an optical light microscope to control the electron beam, for instance focusing it to produce magnified images or electron diffraction patterns. As the wavelength of an electron can be up to 100,000 times smaller than that of visible light, electron microscopes have a much higher resolution of about 0.1 nm, which compares to about 200 nm for light microscopes. ''Electron microscope'' may refer to: * Transmission electron microscope (TEM) where swift electrons go through a thin sample * Scanning transmission electron microscope (STEM) which is similar to TEM with a scanned electron probe * Scanning electron microscope (SEM) which is similar to STEM, but with thick samples * Electron microprobe similar to a SEM, but more for chemical analysis * Low-energy electron microscope (LEEM), used to image surfaces * ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Christian De Duve
Christian René Marie Joseph, Viscount de Duve (2 October 1917 – 4 May 2013) was a Nobel Prize-winning Belgian cytologist and biochemist. He made serendipitous discoveries of two cell organelles, peroxisomes and lysosomes, for which he shared the Nobel Prize in Physiology or Medicine in 1974 with Albert Claude and George E. Palade ("for their discoveries concerning the structural and functional organization of the cell"). In addition to ''peroxisome'' and ''lysosome'', he invented scientific names such as ''autophagy'', ''endocytosis'', and ''exocytosis'' on a single occasion. The son of Belgian refugees during the First World War, de Duve was born in Thames Ditton, Surrey, England. His family returned to Belgium in 1920. He was educated by the Jesuits at Our Lady College, Antwerp, and studied medicine at the Catholic University of Louvain. Upon earning his MD in 1941, he joined research in chemistry, working on insulin and its role in diabetes mellitus. His thesis e ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Albert Claude
Albert Claude (; 24 August 1899 – 22 May 1983) was a Belgian- American cell biologist and medical doctor who shared the Nobel Prize in Physiology or Medicine in 1974 with Christian de Duve and George Emil Palade. His elementary education started in a comprehensive primary school at Longlier, his birthplace. He served in the British Intelligence Service during the First World War, and got imprisoned in concentration camps twice. In recognition of his service, he was granted enrolment at the University of Liège in Belgium to study medicine without any formal education required for the course. He earned his Doctor of Medicine degree in 1928. Devoted to medical research, he initially joined German institutes in Berlin. In 1929 he found an opportunity to join the Rockefeller Institute in New York. At Rockefeller University he made his most groundbreaking achievements in cell biology. In 1930 he developed the technique of cell fractionation, by which he discovered the agent of t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Internet Archive
The Internet Archive is an American 501(c)(3) organization, non-profit organization founded in 1996 by Brewster Kahle that runs a digital library website, archive.org. It provides free access to collections of digitized media including websites, Application software, software applications, music, audiovisual, and print materials. The Archive also advocates a Information wants to be free, free and open Internet. Its mission is committing to provide "universal access to all knowledge". The Internet Archive allows the public to upload and download digital material to its data cluster, but the bulk of its data is collected automatically by its web crawlers, which work to preserve as much of the public web as possible. Its web archiving, web archive, the Wayback Machine, contains hundreds of billions of web captures. The Archive also oversees numerous Internet Archive#Book collections, book digitization projects, collectively one of the world's largest book digitization efforts. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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The Independent
''The Independent'' is a British online newspaper. It was established in 1986 as a national morning printed paper. Nicknamed the ''Indy'', it began as a broadsheet and changed to tabloid format in 2003. The last printed edition was published on Saturday 26 March 2016, leaving only the online edition. The daily edition was named National Newspaper of the Year at the 2004 British Press Awards. ''The Independent'' won the Brand of the Year Award in The Drum Awards for Online Media 2023. History 1980s Launched in 1986, the first issue of ''The Independent'' was published on 7 October in broadsheet format.Dennis Griffiths (ed.) ''The Encyclopedia of the British Press, 1422–1992'', London & Basingstoke: Macmillan, 1992, p. 330. It was produced by Newspaper Publishing plc and created by Andreas Whittam Smith, Stephen Glover and Matthew Symonds. All three partners were former journalists at ''The Daily Telegraph'' who had left the paper towards the end of Lord Hartwell' ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cell Biology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of the structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fiel ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Romanian-American
Romanian Americans () are Americans who have Romanian ancestry. According to the 2023 American Community Survey, 425,738 Americans indicated Romanian as their first or second ancestry, however other sources provide higher estimates, which are most likely more accurate, for the numbers of Romanian Americans in the contemporary United States; for example, the Romanian-American Network supplies a rough estimate of 1.2 million who are fully or partially of Romanian ethnicity. There is also a significant number of people of Romanian Jewish ancestry, estimated at 225,000. History The first Romanian known to have been to what is now the United States was Samuel Damian (also spelled Domien), a former priest. Samuel Damian's name appears as far back as 1748, when he placed an advertisement in the '' South Carolina Gazette'' announcing the electrical demonstrations he planned to give and inviting the public to attend. Letters written in 1753 and 1755 by Benjamin Franklin attest to t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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HonFRMS
The Royal Microscopical Society (RMS) is a learned society for the promotion of microscopy. It was founded in 1839 as the Microscopical Society of London making it the oldest organisation of its kind in the world. In 1866, the Society gained its royal charter and took its current name. Founded as a society of amateurs, its membership consists of individuals of all skill levels in numerous related fields from throughout the world. Every year since 1841, the Society has published its own scientific journal, the '' Journal of Microscopy'', which contains peer-reviewed papers and book reviews. The Society is a registered charity that is dedicated to advancing science, developing careers and supporting wider understanding of science and microscopy through its Outreach activities. Probably the Society's greatest contribution is its standardised 3x1 inches microscope glass slides in 1840, which are still the most widely used size today and known as the "RMS standard". The Royal Micros ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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ForMemRS
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, including mathematics, engineering science, and medical science". Overview Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to :Fellows of the Royal Society, around 8,000 fellows, including eminent scientists Isaac Newton (1672), Benjamin Franklin (1756), Charles Babbage (1816), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Jagadish Chandra Bose (1920), Albert Einstein (1921), Paul Dirac (1930), Subrahmanyan Chandrasekhar (1944), Prasanta Chandra Mahalanobis (1945), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955), Satyendra Nath Bose (1958), and Francis Crick (1959). More recently, fellow ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |