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Elsie N. Ward
Elsie N. Ward (August 8, 1911-April 2,1997) was a microbiologist who contributed to the development of a polio vaccine through her work in Jonas Salk's Virus Research Laboratory at the University of Pittsburgh. Ward's role was to grow poliovirus in monkey tissues. Early life Ward was born in Bellevue, Pennsylvania on August 8, 1911 to Joseph W. Ward and Elsie Ness. Ward received her A.B. with honor from Mount Holyoke College in 1933. She earned an M.A. from Mount Holyoke in 1935. Research Ward was originally trained as a zoologist, and became known for her work culturing cells from monkey hearts, which could then be used to grow the poliovirus. Ward also developed a colorimetric test to track the success of the vaccine. In a 1952 experiment, Ward cared for and assessed the test tubes containing monkey cells mixed with live poliovirus and blood from vaccinated individuals. Acid-sensitive red dye has been added to the tubes to demonstrate the success of the vaccine. A color cha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polio Vaccine
Polio vaccines are vaccines used to prevent poliomyelitis (polio). Two types are used: an inactivated vaccine, inactivated poliovirus given by injection (IPV) and a attenuated vaccine, weakened poliovirus given by mouth (OPV). The World Health Organization (WHO) recommends all children be fully vaccinated against polio. The two vaccines have eliminated polio from most of the world, and reduced the number of cases reported each year from an estimated 350,000 in 1988 to 33 in 2018. The inactivated polio vaccines are very safe. Mild redness or pain may occur at the site of injection. Oral polio vaccines cause about three cases of vaccine-associated paralytic poliomyelitis per million doses given. This compares with 5,000 cases per million who are paralysed following a polio infection. Both types of vaccine are generally safe to give during pregnancy and in those who have HIV/AIDS, but are otherwise well. However, the emergence of circulating vaccine-derived poliovirus (cVDPV), a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jonas Salk
Jonas Edward Salk (; born Jonas Salk; October 28, 1914June 23, 1995) was an American virologist and medical researcher who developed one of the first successful polio vaccines. He was born in New York City and attended the City College of New York and New York University School of Medicine. In 1947, Salk accepted a professorship at the University of Pittsburgh School of Medicine, where he undertook a project beginning in 1948 to determine the number of different types of poliovirus. For the next seven years, Salk devoted himself to developing a vaccine against polio. Salk was immediately hailed as a "miracle worker" when the vaccine's success was first made public in April 1955, and chose to not patent the vaccine or seek any profit from it in order to maximize its global distribution. The National Foundation for Infantile Paralysis and the University of Pittsburgh looked into patenting the vaccine, but since Salk's techniques were not novel, their patent attorney said, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Pittsburgh
The University of Pittsburgh (Pitt) is a Commonwealth System of Higher Education, state-related research university in Pittsburgh, Pennsylvania, United States. The university is composed of seventeen undergraduate and graduate schools and colleges at its Urban university, urban Pittsburgh campus, home to the university's central administration and around 28,000 undergraduate and graduate students. The 132-acre Pittsburgh campus includes various historic buildings that are part of the Schenley Farms Historic District, most notably its 42-story Gothic Revival architecture, Gothic revival centerpiece, the Cathedral of Learning. Pitt is a member of the Association of American Universities and is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Universities – Very high research activity". Pitt traces its roots to the Pittsburgh Academy founded by Hugh Henry Brackenridge in 1787. While the city was still on the History of Pittsburgh#Gatewa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poliovirus
Poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species '' Enterovirus C'', in the family of '' Picornaviridae''. There are three poliovirus serotypes, numbered 1, 2, and 3. Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA (+ssRNA) genome that is about 7500 nucleotides long. The viral particle is about 30 nm in diameter with icosahedral symmetry. Because of its short genome and its simple composition—only a strand of RNA and a nonenveloped icosahedral protein coat encapsulating it—poliovirus is widely regarded as the simplest significant virus. Poliovirus is one of the most well-characterized viruses, and has become a useful model system for understanding the biology of RNA viruses. Replication cycle Poliovirus infects human cells by binding to an immunoglobulin-like receptor, CD155 (also known as the poliovirus receptor or PVR) on the cell surface. Inte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bellevue, Pennsylvania
Bellevue is a borough in Allegheny County, Pennsylvania, United States, along the Ohio River. The population was 8,311 at the 2020 census. A suburb of Pittsburgh, it is part of the Pittsburgh metropolitan area. The borough was incorporated in 1867. There is a public park and library, the Andrew Bayne Memorial Library. History The land on which the borough currently sits was once part of the Depreciation Lands reserved for Revolutionary War veterans. The first landowners in the area were James Robinson and Hugh Henry Brackenridge, purchasing parcels in 1799 and 1792 respectively. At the time of its organization as a borough, Bellevue had exactly the minimum population for such a designation: 300 residents. Residents of the area tried unsuccessfully to obtain improvements from Ross Township, but officials were opposed to development along Venango Trail (today Route 19). In response, Bellevue was incorporated as a borough independent of Ross on September 7, 1867. The name ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mount Holyoke College
Mount Holyoke College is a Private college, private Women's colleges in the United States, women's Liberal arts colleges in the United States, liberal arts college in South Hadley, Massachusetts, United States. It is the oldest member of the historic Seven Sisters (colleges), Seven Sisters colleges, a group of historically women’s colleges in the Northeastern United States. The college was founded in 1837 as the Mount Holyoke Female Seminary by Mary Lyon, a pioneer in education for women. Mount Holyoke is part of the Five College Consortium in Western Massachusetts. Undergraduate admissions are restricted to female, transgender, and Non-binary gender, nonbinary students. In 2014, it became the first member of the Seven Sisters (not counting the coeducational Vassar College) to introduce an admissions policy that was inclusive of transgender students. Graduate programs are open to applicants regardless of gender. The college's campus includes the Mount Holyoke College Art Mu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New York Times
''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of the longest-running newspapers in the United States, the ''Times'' serves as one of the country's Newspaper of record, newspapers of record. , ''The New York Times'' had 9.13 million total and 8.83 million online subscribers, both by significant margins the List of newspapers in the United States, highest numbers for any newspaper in the United States; the total also included 296,330 print subscribers, making the ''Times'' the second-largest newspaper by print circulation in the United States, following ''The Wall Street Journal'', also based in New York City. ''The New York Times'' is published by the New York Times Company; since 1896, the company has been chaired by the Ochs-Sulzberger family, whose current chairman and the paper's publ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thomas Francis Jr
Thomas Francis Jr. (July 15, 1900 October 1, 1969) was an American physician, virologist, and epidemiologist who guided the discovery and development of the polio vaccine being worked on by his student Jonas Salk. Francis was the first person to isolate influenza virus in the United States, and in 1940 showed that there are other strains of influenza, and took part in the development of influenza vaccines. Life Francis grew up in New Castle in western Pennsylvania, graduated from New Castle High School in 1917 and Allegheny College on scholarship in 1921, and received his medical degree from Yale University in 1925. Afterwards he joined an elite research team at the Rockefeller Institute, first doing research on vaccines against bacterial pneumonia, later he took up influenza research. He became the first American to isolate human flu virus. From 1938 to 1941 he was professor of bacteriology and chair of the department of the New York University College of Medicine. In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Michigan
The University of Michigan (U-M, U of M, or Michigan) is a public university, public research university in Ann Arbor, Michigan, United States. Founded in 1817, it is the oldest institution of higher education in the state. The University of Michigan is one of the earliest American research universities and is a founding member of the Association of American Universities. In the fall of 2023, the university employed 8,189 faculty members and enrolled 52,065 students in its programs. The university is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Universities – Very high research activity". It consists of nineteen colleges and offers 250 degree programs at the undergraduate and graduate levels. The university is Higher education accreditation in the United States, accredited by the Higher Learning Commission. In 2021, it ranked third among American universities in List of countries by research and development spending, research expe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mount Holyoke College Alumni
Mount is often used as part of the name of specific mountains, e.g. Mount Everest. Mount or Mounts may also refer to: Places * Mount, Cornwall, a village in Warleggan parish, England * Mount, Perranzabuloe, a hamlet in Perranzabuloe parish, Cornwall, England People * Mount (surname) * William L. Mounts (1862–1929), American lawyer and politician Computing and software * Mount (computing), the process of making a file system accessible * Mount (Unix), the utility in Unix-like operating systems which mounts file systems Books * ''Mount!'', a 2016 novel by Jilly Cooper Displays and equipment * Mount, a fixed point for attaching equipment, such as a hardpoint on an airframe * Mounting board, in picture framing * Mount, a hanging scroll for mounting paintings * Mount, to display an item on a heavy backing such as foamcore, e.g.: ** To pin a biological specimen, on a heavy backing in a stretched stable position for ease of dissection or display ** To prepare dead an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Women Medical Researchers
A woman is an adult female human. Before adulthood, a female child or Adolescence, adolescent is referred to as a girl. Typically, women are of the female sex and inherit a pair of X chromosomes, one from each parent, and women with functional uteruses are capable of pregnancy and giving childbirth, birth from puberty until menopause. More generally, sex differentiation of the female fetus is governed by the lack of a present, or functioning, ''SRY'' gene on either one of the respective sex chromosomes. Sex differences in human physiology, Female anatomy is distinguished from male anatomy by the female reproductive system, which includes the ovaries, fallopian tubes, uterus, vagina, and vulva. An adult woman generally has a wider pelvis, broader hips, and larger breasts than an adult man. These characteristics facilitate childbirth and breastfeeding. Women typically have less facial and other body hair, have a higher body fat composition, and are on average shorter and less ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
