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Ehrlichia Wisconsin HM543746
''Ehrlichia'' Wisconsin HM543746 is an unnamed tick bacterium that spread through Minnesota and Wisconsin in 2009 and is similar to '' Ehrlichia muris''. Researchers took more than 4000 blood samples from people who appeared to have ehrlichiosis or anaplasmosis, and used 697 ticks from both states as test subjects. The researchers, working at the Mayo Clinic, used molecular methods, culturing, and serological testing. The research was conducted after technologist Carol Werner noticed an unnatural Ehrlichia polymerase chain reaction result. The investigation arrived at the discovery of the new bacterium because the research showed that four of the patients were infected by a new bacterium; their symptoms in 2009 including fevers, headaches, fatigue, nausea, and vomiting. All four of the patients survived by being treated with doxycycline. The results were published in ''The New England Journal of Medicine'' and brought up in a Health Alert Network public health announcement. The ...
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Tick
Ticks are parasitic arachnids of the order Ixodida. They are part of the mite superorder Parasitiformes. Adult ticks are approximately 3 to 5 mm in length depending on age, sex, and species, but can become larger when engorged. Ticks are external parasites, living by feeding on the blood of mammals, birds, and sometimes reptiles and amphibians. The timing of the origin of ticks is uncertain, though the oldest known tick fossils are around 100 million years old, and come from the Cretaceous period. Ticks are widely distributed around the world, especially in warm, humid climates. Ticks belong to two major families: the Ixodidae, or hard ticks, and the Argasidae, or soft ticks. '' Nuttalliella'', a genus of tick from southern Africa, is the only member of the family Nuttalliellidae, and represents the most primitive living lineage of ticks. Adults have ovoid/pear-shaped bodies (idiosomas) which become engorged with blood when they feed, and eight legs. Their cephalotho ...
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The New England Journal Of Medicine
''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. Founded in 1812, the journal is among the most prestigious peer-reviewed medical journals. Its 2023 impact factor was 96.2, ranking it 2nd out of 168 journals in the category "Medicine, General & Internal". History In September 1811, Boston physician John Collins Warren, along with James Jackson, submitted a formal prospectus to establish the ''New England Journal of Medicine and Surgery and Collateral Branches of Science'' as a medical and philosophical journal. Subsequently, the first issue of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' was published in January 1812. The journal was published quarterly. In 1823, another publication, the ''Boston Medical Intelligencer'', appeared under the editorship of Jerome V. C. Smith. The editors of the ''New England Journal of Medicine and Surgery and th ...
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Ehrlichia Ewingii
''Ehrlichia ewingii'' is a species of Rickettsiales bacteria. It has recently been associated with human infection, and can be detected via PCR serological testing. The name ''Ehrlichia ewingii'' was proposed in 1992. Taxonomy and characterization Taxonomy The current classification is Bacteria, Pseudomonadota, Alphaproteobacteria, Rickettsiales, Ehrlichiaceae, ''Ehrlichia ewingii''. Classification of different members of the genus '' Ehrlichia'' has been disputed, however, it is generally agreed that close relatives of ''Ehrlichia ewingii'' are ''Ehrlichia chaffeensis'' and '' Ehrlichia canis''. It is also closely related to ''Wolbachia'', '' Anaplasma'', and '' Neorickettsia'' bacteria, with ''Rickettsia'' as a more distant genus. Characterization Species in the family Anaplasmataceae have unique characteristics that can help differentiate them from other families including: sensitivity to mechanical stress, changes in osmolarity, and thawing.  All ' ...
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Ehrlichia Chaffeensis
''Ehrlichia chaffeensis'' is an obligate intracellular, Gram-negative species of Rickettsiales bacteria. It is a zoonotic pathogen transmitted to humans by the lone star tick (''Amblyomma americanum''). It is the causative agent of human monocytic ehrlichiosis. Human monocytic ehrlichiosis caused by ''E. chaffeensis'' is known to spread through tick infection primarily in the Southern, South-central and Mid-Atlantic regions of the United States. In recent years, the lone star tick has expanded its range along the East Coast to New England, putting more humans at risk for tick-borne infections.Little, S. E. (2007, January). ''New developments in managing vector-borne diseases''. Retrieved from http://www.iknowledgenow.com/tocnavc2007smallanimal.cfm It is named for Fort Chaffee, where the bacterium was first discovered in blood samples of infected patients. Transmission cycle ''E. chaffeensis'' is maintained in nature through a complex zoonotic relationship. The white-tailed d ...
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Ixodes Scapularis
''Ixodes scapularis'' is a hard-bodied tick found in much of the eastern half of North America. It is commonly known as the deer tick, owing to its habit of parasitizing the white-tailed deer. It is also sometimes known as the black-legged tick (although some people reserve that specific term for ''Ixodes pacificus'', which is found on the west coast of the US), and as the bear tick in some parts of the US. It was also named ''Ixodes dammini'' until it was shown to be the same species in 1993. It is a Vector (epidemiology), vector for several diseases of animals, including humans (Lyme disease, babesiosis, Human granulocytic anaplasmosis, anaplasmosis, Powassan virus, Powassan virus disease, etc.). It is also known to parasitize mice, lizards, migratory birds, etc. especially while the tick is in the larval or nymphal stage. Description As a nymph and adult, ''Ixodes scapularis'' has eight legs, while larvae have six. Unlike ticks from other genera, deer ticks do not have eyes ...
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Entomologist
Entomology (from Ancient Greek ἔντομον (''éntomon''), meaning "insect", and -logy from λόγος (''lógos''), meaning "study") is the branch of zoology that focuses on insects. Those who study entomology are known as entomologists. In the past, the term ''insect'' was less specific, and historically the definition of entomology would also include the study of animals in other arthropod groups, such as arachnids, myriapods, and crustaceans. The field is also referred to as insectology in American English, while in British English insectology implies the study of the relationships between insects and humans. Over 1.3million insect species have been described by entomology. History Entomology is rooted in nearly all human cultures from prehistoric times, primarily in the context of agriculture (especially biological control and beekeeping). The natural Roman philosopher Pliny the Elder (23–79 CE) wrote a book on the kinds of insects, while the scientist of Kufa, ...
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Doxycycline
Doxycycline is a Broad-spectrum antibiotic, broad-spectrum antibiotic of the Tetracycline antibiotics, tetracycline class used in the treatment of infections caused by bacteria and certain parasites. It is used to treat pneumonia, bacterial pneumonia, acne vulgaris, acne, chlamydia infections, Lyme disease, cholera, typhus, and syphilis. It is also used to prevent malaria. Doxycycline may be taken Oral administration, by mouth or by intravenous, injection into a vein. Common side effects include diarrhea, nausea, vomiting, abdominal pain, and an increased risk of sunburn. Use during pregnancy is not recommended. Like other agents of the tetracycline class, it either slows or kills bacteria by inhibiting protein production. It kills malaria by targeting a plastid organelle, the apicoplast. Doxycycline was patented in 1957 and came into commercial use in 1967. It is on the WHO Model List of Essential Medicines, World Health Organization's List of Essential Medicines. Doxycyc ...
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Nausea
Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit. It can be a debilitating symptom if prolonged and has been described as placing discomfort on the chest, abdomen, or back of the throat. Over 30 definitions of nausea were proposed in a 2011 book on the topic. Nausea is a non-specific symptom, which means that it has many possible causes. Some common causes of nausea are gastroenteritis and other gastrointestinal disorders, food poisoning, motion sickness, dizziness, migraine, fainting, low blood sugar, anxiety, hyperthermia, dehydration and lack of sleep. Nausea is a side effect of many medications including chemotherapy, or morning sickness in early pregnancy. Nausea may also be caused by disgust and depression. Medications taken to prevent and treat nausea and vomiting are called antiemetics. The most commonly prescribed antiemetics in the US are promethazine, metoclopramide, and the newer ondansetron. The word na ...
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Fatigue (medical)
Fatigue is a state of tiredness (which is not sleepiness), exhaustion or loss of energy. It is a symptom of any of various diseases; it is not a disease in itself. Fatigue (in the medical sense) is sometimes associated with medical conditions including autoimmune disease, organ failure, chronic pain conditions, mood disorders, heart disease, infectious diseases, and post-infectious-disease states. However, fatigue is complex and in up to a third of primary care cases no medical or psychiatric diagnosis is found. Fatigue (in the general usage sense of normal tiredness) often follows prolonged physical or mental activity. Physical fatigue results from muscle fatigue brought about by intense physical activity. Mental fatigue results from prolonged periods of cognitive activity which impairs cognitive ability, can manifest as sleepiness, lethargy, or directed attention fatigue, and can also impair physical performance. Definition Fatigue in a medical context is used to ...
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Science Daily
''ScienceDaily'' is an American website launched in 1995 that aggregates press releases and publishes lightly edited press releases (a practice called churnalism) about science, similar to Phys.org and EurekAlert!. History The site was founded by married couple Dan and Michele Hogan in 1995; Dan Hogan formerly worked in the public affairs department of Jackson Laboratory writing press releases. The site makes money from selling advertisements. the site said that it had grown "from a two-person operation to a full-fledged news business with worldwide contributors". At the time, it was run out of the Hogans' home, had no reporters, and only reprinted press releases. In 2012, Quantcast ranked it at 614 with 2.6 million U.S. visitors. Sections As of August 2023, ''ScienceDaily'' mainly has five sections, Health, Tech, Enviro, Society, and Quirky, the last of which includes the top news. References External links * Alexa - ScienceDaily��{{Webarchive, url=https://web.a ...
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Polymerase Chain Reaction
The polymerase chain reaction (PCR) is a method widely used to make millions to billions of copies of a specific DNA sample rapidly, allowing scientists to amplify a very small sample of DNA (or a part of it) sufficiently to enable detailed study. PCR was invented in 1983 by American biochemist Kary Mullis at Cetus Corporation. Mullis and biochemist Michael Smith (chemist), Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of Ancient DNA, ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications including biomedical research and forensic ...
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Serological
Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given microorganism), against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease). In either case, the procedure is simple. Serological tests Serological tests are diagnostic methods that are used to identify antibodies and antigens in a patient's sample. Serological tests may be performed to diagnose infections and autoimmune illnesses, to check if a person has immunity to certain diseases, and in many other situations, such as determining an individual's blood type. Serological tests may also be used in forensic serology to investigate crime scene evidence. Several methods can be used to detect antibodies and antigens, including ELISA, agglutinatio ...
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