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Effector
Effector may refer to: * Effector (biology), a molecule that binds to a protein and thereby alters the activity of that protein * ''Effector'' (album), a music album by the Experimental Techno group Download * ''EFFector'', a publication of the Electronic Frontier Foundation See also * Effexor, a brand name for the antidepressant venlafaxine * Bacterial effector protein, proteins secreted by bacterial pathogens into the cells of their host * Effector cell * End effector, the device at the end of a robotic arm *Affect (other) Affect may refer to: * Affect (education) * Affect (linguistics), attitude or emotion that a speaker brings to an utterance * Affect (philosophy) * Affect (psychology), the experience of feeling or emotion ** Affect display, signs of emotion, such ...
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Bacterial Effector Protein
Bacterial effectors are proteins secreted by pathogenic bacteria into the cells of their host, usually using a type 3 secretion system (TTSS/T3SS), a type 4 secretion system (TFSS/T4SS) or a Type VI secretion system (T6SS). Some bacteria inject only a few effectors into their host’s cells while others may inject dozens or even hundreds. Effector proteins may have many different activities, but usually help the pathogen to invade host tissue, suppress its immune system, or otherwise help the pathogen to survive. Effector proteins are usually critical for virulence. For instance, in the causative agent of plague (''Yersinia pestis''), the loss of the T3SS is sufficient to render the bacteria completely avirulent, even when they are directly introduced into the bloodstream. Gram negative microbes are also suspected to deploy bacterial outer membrane vesicles to translocate effector proteins and virulence factors via a membrane vesicle trafficking secretory pathway, in order to modi ...
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Effector (biology)
In biochemistry, an effector molecule is usually a small molecule that selectively binds to a protein and regulates its biological activity. In this manner, effector molecules act as ligands that can increase or decrease enzyme activity, gene expression, or cell signaling. Effector molecules can also directly regulate the activity of some mRNA molecules ( riboswitches). Other examples of effector functions in biochemistry include hormone signaling and immune response. In some cases, specific proteins serve the same role as effector molecules (note: small molecules refers to organic compounds similar in size to amino acids or RNA strands. Most effector molecules are therefor much smaller than individual proteins, which consist of many amino acids). One example of this is in cellular signal transduction cascades. The term ''effector'' is used in other fields of biology. For instance, the effector end of a neuron is the terminus where an axon makes contact with the muscle or ...
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Robot End Effector
In robotics, an end effector is the device at the end of a robotic arm, designed to interact with the environment. The exact nature of this device depends on the application of the robot. In the strict definition, which originates from serial robotic manipulators, the end effector means the last link (or end) of the robot. At this endpoint, the tools are attached. In a wider sense, an end effector can be seen as the part of a robot that interacts with the work environment. This does not refer to the wheels of a mobile robot or the feet of a humanoid robot, which are not end effectors but rather part of a robot's mobility. End effectors may consist of a gripper or a tool. When referring to robotic prehension there are four general categories of robot grippers: # Impactive: jaws or claws which physically grasp by direct impact upon the object. # Ingressive: pins, needles or hackles which physically penetrate the surface of the object (used in textile, carbon, and glass fiber ha ...
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Effector Cell
In cell biology, an effector cell is any of various types of cell that actively responds to a stimulus and effects some change (brings it about). Examples of effector cells include: * The muscle, gland or organ cell capable of responding to a stimulus at the terminal end of an efferent nerve fiber * Plasma cell, an effector B cell in the immune system * Effector T cells, T cells that actively respond to a stimulus * Cytokine-induced killer cells, strongly productive cytotoxic effector cells that are capable of lysing tumor cells * Microglia, a glial effector cell that reconstructs the Central nervous system after a bone marrow transplant * Fibroblast, a cell that is most commonly found within connective tissue * Mast cell, the primary effector cell involved in the development of asthma Cytokine-induced killer cells as effector cells As an effector cell, cytokine-induced killer cells can recognize infected or malignant cells even when antibodies and major histocompatibilit ...
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Electronic Frontier Foundation
The Electronic Frontier Foundation (EFF) is an international non-profit digital rights group based in San Francisco, California. The foundation was formed on 10 July 1990 by John Gilmore, John Perry Barlow and Mitch Kapor to promote Internet civil liberties. The EFF provides funds for legal defense in court, presents ''amicus curiae'' briefs, defends individuals and new technologies from what it considers abusive legal threats, works to expose government malfeasance, provides guidance to the government and courts, organizes political action and mass mailings, supports some new technologies which it believes preserve personal freedoms and online civil liberties, maintains a database and web sites of related news and information, monitors and challenges potential legislation that it believes would infringe on personal liberties and fair use and solicits a list of what it considers abusive patents with intentions to defeat those that it considers without merit. History ...
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Effector (album)
''Effector'' is an electronica album by Canadian electronic music group Download. Track listing # "Carrier Tone" – 4:02 # "Muscaria" – 5:09 # "Vagator" – 6:12 # "Ego Dissolve" – 5:31 # "The Guide" – 5:27 # "Chrysanthemum" – 5:03 # "Ayahuasca" – 3:55 # "Two Worlds Collide" – 6:44 # "Affirmed" – 4:04 All songs by cEvin Key & Phil Western, except for "Ego Dissolve" and "Ayahuasca" by Key, Western & Van Rooy. Personnel * cEvin Key *Phil Western Phillip Charles Western (August 12, 1971 – February 4, 2019) was a Canadian musician, based in Vancouver and a founding member of the bands Download, PlatEAU, Frozen Rabbit, and Off and Gone. Biography Having started his career as a drumm ... Guests *William van Rooy - additional electronics (4, 7) Notes The cover is a photograph of an amusement ride in Dresden, taken by Anthony Valcic using a very slow shutter speed. "Muscaria" begins with a backwards-masked sample from Quebec blues-rock band Offenba ...
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Effexor
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. It may also be used for chronic pain. It is taken by mouth. It is also available as the salt venlafaxine besylate in an extended-release formulation (Venbysi XR). Common side effects include loss of appetite, constipation, dry mouth, dizziness, sweating, insomnia, drowsiness and sexual problems. Severe side effects include an increased risk of suicide, mania, and serotonin syndrome. Antidepressant withdrawal syndrome may occur if stopped. There are concerns that use during the later part of pregnancy can harm the baby. How it works is not entirely clear, but it seems to be related to the potentiation of the activity of some neurotransmitters in the brain. Venlafaxine was approved for medical use in ...
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