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Edwin Krebs
Edwin Gerhard Krebs (June 6, 1918 – December 21, 2009) was an American biochemist. He received the Albert Lasker Award for Basic Medical Research and the Louisa Gross Horwitz Prize of Columbia University in 1989 together with Alfred Gilman and, together with his collaborator Edmond H. Fischer, was awarded the Nobel Prize in Physiology or Medicine in 1992 for describing how reversible phosphorylation works as a switch to activate proteins and regulate various cellular processes. Early life and education Krebs was born in Lansing, Iowa, the third child of William Carl Krebs, a Presbyterian minister and Louise Helen (Stegeman) Krebs. The family moved frequently due to the nature of his father's work, though they settled in Greenville, Illinois when Krebs was six and remained there until his father's unexpected death in 1933. Louise Krebs decided to move her family to Urbana, Illinois, where Krebs's elder brothers were attending the University of Illinois Urbana–Champai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lansing, Iowa
Lansing is a city in Lansing Township, Allamakee County, Iowa, United States. The population was 968 at the time of the 2020 census. History Lansing was platted ''circa'' 1851. The city was so named because the first settler was a native of Lansing, Michigan. Lansing became incorporated as a city on July 1, 1867. Joseph "Diamond Jo" Reynolds, namesake of the famous Diamond Jo steamship line, built his first boat in Lansing and named it for the town. Geography According to the United States Census Bureau, the city has a total area of , of which is land and is water. Mount Hosmer is located on the north end of Lansing. Demographics 2020 census As of the census of 2020, there were 968 people, 442 households, and 235 families residing in the city. The population density was 908.8 inhabitants per square mile (350.9/km2). There were 639 housing units at an average density of 599.9 per square mile (231.6/km2). The racial makeup of the city was 96.1% White, 0.8% Black or Afric ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edmond H
Edmond may refer to: Arts and entertainment * ''Edmond'' (play), a 1982 play by David Mamet ** ''Edmond'' (film), a 2005 film based on the 1982 play * '' E.d.M.O.N.D'', a 2013 EP by Edmond Leung * ''Edmond'', a 2016 play by Alexis Michalik ** ''Edmond'', a 2019 film adaptation of the play, written and directed by Michalik * Berlin Edmond (born 1992), American YouTuber known online as Berleezy Places * Edmond, Kansas * Edmond, Oklahoma * Edmonds, Washington * Edmond, West Virginia Others * Edmond (given name) * ''Edmond'' (1833), a passenger sailing ship that sank off the coast of Ireland in 1850 * Edmond, a racehorse that was the joint favourite for the 2001 Grand National See also *Edmund (other) *Edward (other) Edward is an English given name. Edward may also refer to: * ''Edward'' (ballad), a traditional murder ballad * ''Edward'' (EP), by British singer-songwriter Emmy the Great * Edward (mango), a mango cultivar * Lake Edward Lake Edward (locally ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phosphorylase
In biochemistry, phosphorylases are enzymes that catalyze the addition of a phosphate group from an inorganic phosphate (phosphate+hydrogen) to an acceptor. :A-B + P A + P-B They include allosteric enzymes that catalyze the production of glucose-1-phosphate from a glucan such as glycogen, starch or maltodextrin. Phosphorylase is also a common name used for glycogen phosphorylase in honor of Earl W. Sutherland Jr., who in the late 1930s discovered it as the first phosphorylase. Function Phosphorylases should not be confused with phosphatases, which remove phosphate groups. In more general terms, phosphorylases are enzymes that catalyze the addition of a phosphate group from an inorganic phosphate (phosphate + hydrogen) to an acceptor, not to be confused with a phosphatase (a hydrolase) or a kinase (a phosphotransferase). A phosphatase removes a phosphate group from a donor using water, whereas a kinase transfers a phosphate group from a donor (usually ATP) to an accep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protamine
Protamines are small, arginine-rich, nuclear proteins that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization. They may allow for denser packaging of DNA in the spermatozoon than histones, but they must be decompressed before the genetic data can be used for protein synthesis. However, part of the sperm's genome is packaged by histones (10-15% in humans and other primates) thought to bind genes that are essential for early embryonic development. Protamine and protamine-like (PL) proteins are collectively known as the sperm-specific nuclear basic proteins (SNBPs). The PL proteins are intermediate in structure between protamine and Histone H1. The C-terminal domain of PL could be the precursor of vertebrate protamine. Spermatogenesis During the formation of sperm, protamine binds to the phosphate backbone of DNA using the arginine-rich domain as an anchor. DNA is then folded into a toroi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gerty Cori
Gerty Theresa Cori (; August 15, 1896 – October 26, 1957) was a Bohemian-Austrian and American biochemist who in 1947 was the third woman to win a Nobel Prize in science, and the first woman to be awarded the Nobel Prize in Physiology or Medicine, for her role in the "discovery of the course of the catalytic conversion of glycogen". Cori was born in Prague, the capital of Bohemia within the Austro-Hungarian Empire. Growing up at a time when women were marginalized and allowed few educational opportunities, she gained admittance to medical school, where she met her future husband Carl Ferdinand Cori in an anatomy class. Upon their graduation in 1920, they married. Because of deteriorating conditions in Europe, the couple emigrated to the United States in 1922. Gerty Cori continued her early interest in medical research, collaborating in the laboratory with Carl. She published research coauthored with her husband, as well as publishing singly. Unlike her husband, she had diff ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carl Cori
Carl Ferdinand Cori, ForMemRS (December 5, 1896 – October 20, 1984) was a Czech-American biochemist and pharmacologist. He, together with his wife Gerty Cori and Argentine physiologist Bernardo Houssay, received a Nobel Prize in 1947 for their discovery of how the glucose derivative glycogen (animal starch) is broken down and resynthesized in the body for use as a store and source of energy. In 2004, both Coris were designated a National Historic Chemical Landmark in recognition of their work that elucidated carbohydrate metabolism. Education and early life Carl Ferdinand Cori was born on December 5, 1896, in Prague, Austria-Hungary (now the Czech Republic). Carl was the son of Carl Isidor Cori (1865, Brüx – 1954, Vienna), a zoologist, and Maria Cori (née Lippich; 1870, Graz – 1922, Prague), a daughter of the Italian-Bohemian/Austrian/Slovenian /Hungarian physician (1838, Padua – 1913, Prague). The Cori family came from the Papal State (later the Roman Repub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Navy
The United States Navy (USN) is the naval warfare, maritime military branch, service branch of the United States Department of Defense. It is the world's most powerful navy with the largest Displacement (ship), displacement, at 4.5 million tons in 2021. It has the world's largest aircraft carrier fleet, with List of aircraft carriers in service, eleven in service, one undergoing trials, two new carriers under construction, and six other carriers planned as of 2024. With 336,978 personnel on active duty and 101,583 in the Ready Reserve, the U.S. Navy is the third largest of the United States military service branches in terms of personnel. It has 299 deployable combat vessels and about 4,012 operational aircraft as of 18 July 2023. The U.S. Navy is one of six United States Armed Forces, armed forces of the United States and one of eight uniformed services of the United States. The United States Navy traces its origins to the Continental Navy, which was established during ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barnes-Jewish Hospital
Barnes-Jewish Hospital is the largest hospital in the U.S. state of Missouri. Located in the Central West End, St. Louis, Central West End neighborhood of St. Louis, it is the adult teaching hospital for Washington University School of Medicine and a major component of Washington University Medical Center. ''U.S. News & World Report'' ranked Barnes-Jewish among the top hospitals in the nation in its annual report in 2018 and 2022. Capacity Barnes-Jewish Hospital is a member of BJC HealthCare and is located on the campus of the Washington University Medical Center. Barnes-Jewish is the largest private employer in Greater St. Louis, employing 10,125 people in 2018, including 1,723 attending physicians. It is responsible for the education of 1,129 medical residency, interns, medical resident, residents, and fellows. As of 2018, the hospital had 1,266 beds with a staff of 12,125. History Barnes-Jewish was formed by the merger of two hospitals, Barnes Hospital and The Jewish Ho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Chemistry
Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic matter, organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; Greeves, N. and Warren, S. (2012) ''Organic Chemistry''. Oxford University Press. pp. 1–15. . Study of structure determines their structural formula. Study of properties includes Physical property, physical and Chemical property, chemical properties, and evaluation of Reactivity (chemistry), chemical reactivity to understand their behavior. The study of organic reactions includes the organic synthesis, chemical synthesis of natural products, drugs, and polymers, and study of individual organic molecules in the laboratory and via theoretical (in silico) study. The range of chemicals studied chemistry includes hydrocarbons (compounds containing only carbon and hydrogen) as well as compounds based on carbon, but a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urbana High School (Illinois)
Urbana High School is the only public high school in Urbana, Illinois and was established in 1872. History Urbana High School's current building was built in 1914. It was designed by architect Joseph Royer (architect), Joseph Royer who also designed many other buildings in the area including the Urbana Free Library and the Champaign County Court House. The architecture of Urbana High School is of the Tudor style, defined primarily by the towers over the main entrance and the flattened point arches over the doors. An addition was built in 1916 which included a gymnasium and swimming pool. Due to increasing enrollment, further additions were built in 1955 and 1965. In 1988, an enclosed athletic area was added while the old gymnasium/pool wing was converted into classrooms. The entire building was also renovated to meet safety codes. During the renovation, areas that had been sealed off during previous construction revealed graffiti dating back to around the 1950s. The Urbana Pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urbana, Illinois
Urbana ( ) is a city in Champaign County, Illinois, United States, and its county seat. As of the 2020 census, Urbana had a population of 38,336. It is a principal city of the Champaign–Urbana metropolitan area, which had 236,000 residents in 2020. Urbana is notable for sharing the main campus of the University of Illinois with its twin city of Champaign. History The Urbana area was first settled by Europeans in 1822, when it was called "Big Grove".McGinty, Alice"The Story of Champaign-Urbana" Champaign Public Library When the county of Champaign was organized in 1833, the county seat was located on 40 acres of land, 20 acres donated by William T. Webber and 20 acres by M. W. Busey, considered to be the city's founder, and the name "Urbana" was adopted after Urbana, Ohio, the hometown of State Senator John W. Vance, who authored the Enabling Act creating Champaign County. The creation of the new town was celebrated for the first time on July 4, 1833. Stores began open ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Greenville, Illinois
: Greenville is a city in Bond County, Illinois, United States, east of St. Louis. The population as of the 2020 census was 7,083, up from 7,000 at the 2010 census. It is the county seat of Bond County. Greenville is part of the St. Louis Metropolitan Statistical Area. It is also considered part of the Metro East region of Illinois. Greenville celebrated its Bicentennial in 2015 as one of the oldest communities in Illinois. It is home to Greenville University, the Richard Bock Museum, the American Farm Heritage Museum, the Armed Forces Museum and the Demoulin Museum and a federal prison, Federal Correctional Institution, Greenville (FCI Greenville). It is also home to internationally known companies, including Nevco Scoreboard, the largest privately owned scoreboard company in the world, and DeMoulin Brothers, the world's oldest and largest manufacturer of band uniforms. History Greenville was founded by George Davidson in 1815 in what was then the Illinois Territory, whe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
