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Edward B. Lewis
Edward Butts Lewis (May 20, 1918 – July 21, 2004) was an American geneticist, a corecipient of the 1995 Nobel Prize in Physiology or Medicine. He helped to found the field of evolutionary developmental biology. Early life Lewis was born in Wilkes-Barre, Pennsylvania, the second son of Laura Mary Lewis (née Histed) and Edward Butts Lewis, a watchmaker-jeweler. His full name was supposed to be Edward Butts Lewis Jr., but his birth certificate was incorrectly filled out with "B." as his middle name. Lewis graduated from E. L. Meyers High School. Education and career He received a BA in Biostatistics from the University of Minnesota in 1939, where he worked on ''Drosophila melanogaster'' in the lab of C.P. Oliver. In 1942 Lewis received a PhD from California Institute of Technology (Caltech), working under the guidance of Alfred Sturtevant. In 1939, Edward B. Lewis arrived at Caltech and finished his PhD within three years. Lewis enrolled in the U.S. Army Air Corps train ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wilkes-Barre, Pennsylvania
Wilkes-Barre ( , alternatively or ) is a city in Luzerne County, Pennsylvania, United States, and its county seat. Located at the center of the Wyoming Valley in Northeastern Pennsylvania, it had a population of 44,328 in the 2020 census. It is the second-largest city, after Scranton, Pennsylvania, Scranton, in the Wyoming Valley, Scranton–Wilkes-Barre–Hazleton, PA Metropolitan Statistical Area, which had a population of 567,559 as of the 2020 United States census, 2020 census, making it the fifth-largest metropolitan area in Pennsylvania after the Delaware Valley, Greater Pittsburgh, the Lehigh Valley, and Harrisburg–Carlisle metropolitan statistical area, Greater Harrisburg. The contiguous network of five City, cities and more than 40 boroughs all built in a straight line in Northeastern Pennsylvania's urban core act, culturally and logistically as one continuous city, so while the city of Wilkes-Barre itself is a mid-sized city, the larger Scranton/Wilkes-Barre Urban ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features Peer review, peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2022 ''Journal Citation Reports'' (with an ascribed impact factor of 50.5), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in the autumn of 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander MacMillan (publisher), Alexander MacMillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the j ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atomic Bombings Of Hiroshima And Nagasaki
On 6 and 9 August 1945, the United States detonated two atomic bombs over the Japanese cities of Hiroshima and Nagasaki, respectively, during World War II. The aerial bombings killed between 150,000 and 246,000 people, most of whom were civilians, and remain the only uses of Nuclear warfare, nuclear weapons in an armed conflict. Surrender of Japan, Japan announced its surrender to the Allies on 15 August, six days after the bombing of Nagasaki and the Soviet–Japanese War, Soviet Union's declaration of war against Japan and Soviet invasion of Manchuria, invasion of Manchuria. The Japanese government signed an Japanese Instrument of Surrender, instrument of surrender on 2 September, End of World War II in Asia, ending the war. In the final year of World War II, the Allies of World War II, Allies prepared for a costly Operation Downfall, invasion of the Japanese mainland. This undertaking was preceded by a Air raids on Japan, conventional bombing and firebombing campaign that de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nuclear Fallout
Nuclear fallout is residual radioactive material that is created by the reactions producing a nuclear explosion. It is initially present in the mushroom cloud, radioactive cloud created by the explosion, and "falls out" of the cloud as it is moved by the atmosphere in the minutes, hours, and days after the explosion. The bulk of the radioactivity from nuclear fallout comes from fission products, which are created by the nuclear fission reactions of the nuclear device. Un-fissioned bomb fuel (such as plutonium and uranium), and radioactive isotopes created by neutron activation, make up a smaller amount of the radioactive content of fallout. The amount of fallout and its distribution is dependent on several factors, including the overall yield of the weapon, the fission yield of the weapon, the height of burst of the weapon, and meteorological conditions. Fallout can have serious human health consequences on both short- and long-term time scales, and can cause radioactive conta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
X-rays
An X-ray (also known in many languages as Röntgen radiation) is a form of high-energy electromagnetic radiation with a wavelength shorter than those of ultraviolet rays and longer than those of gamma rays. Roughly, X-rays have a wavelength ranging from 10 Nanometre, nanometers to 10 Picometre, picometers, corresponding to frequency, frequencies in the range of 30 Hertz, petahertz to 30 Hertz, exahertz ( to ) and photon energies in the range of 100 electronvolt, eV to 100 keV, respectively. X-rays were discovered in 1895 in science, 1895 by the German scientist Wilhelm Röntgen, Wilhelm Conrad Röntgen, who named it ''X-radiation'' to signify an unknown type of radiation.Novelline, Robert (1997). ''Squire's Fundamentals of Radiology''. Harvard University Press. 5th edition. . X-rays can penetrate many solid substances such as construction materials and living tissue, so X-ray radiography is widely used in medical diagnostics (e.g., checking for Bo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radiation
In physics, radiation is the emission or transmission of energy in the form of waves or particles through space or a material medium. This includes: * ''electromagnetic radiation'' consisting of photons, such as radio waves, microwaves, infrared, visible light, ultraviolet, x-rays, and Gamma ray, gamma radiation (γ) * ''particle radiation'' consisting of particles of non-zero rest energy, such as alpha radiation (α), beta radiation (β), proton radiation and neutron radiation * ''acoustics, acoustic radiation'', such as ultrasound, sound, and seismic waves, all dependent on a physical transmission medium * ''gravitational radiation'', in the form of gravitational waves, ripples in spacetime Radiation is often categorized as either ''ionizing radiation, ionizing'' or ''non-ionizing radiation, non-ionizing'' depending on the energy of the radiated particles. Ionizing radiation carries more than 10 electron volt, electron volts (eV), which is enough to ionize atoms and molecul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of Regeneration (biology), regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryogenesis, embryonic development of animals are: tissue patterning (via regional specification and patterned cellular differentiation, cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Phenotypic trait, Trait inheritance and Molecular genetics, molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the Cell (bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Complementation (genetics)
Complementation refers to a genetics, genetic process when two strain (biology), strains of an organism with different homozygous recessive mutations that produce the same mutant phenotype (for example, a change in wing structure in flies) have offspring that express the wild-type phenotype when mated or crossed. Complementation will ordinarily occur if the mutations are in different genes (intergenic complementation). Complementation may also occur if the two mutations are at different sites within the same gene (intragenic complementation), but this effect is usually weaker than that of intergenic complementation. When the mutations are in different genes, each strain's genome supplies the wild-type allele to "complement" the mutated allele of the other strain's genome. Since the mutations are recessive, the offspring will display the wild-type phenotype. A complementation test (sometimes called a "Cistron, cis-trans" test) can test whether the mutations in two strains are in d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homeotic Gene
Homeotic genes are genes which regulate the development of anatomical structures in various organisms such as echinoderms, insects, mammals, and plants. Homeotic genes often encode transcription factor proteins, and these proteins affect development by regulating downstream gene networks involved in body patterning. Mutations in homeotic genes cause displaced body parts (homeosis), such as antennae growing at the posterior of the fly instead of at the head. Mutations that lead to development of ectopic structures are usually lethal. Types There are several subsets of homeotic genes. They include many of the Hox and ParaHox genes that are important for segmentation. Hox genes are found in bilateral animals, including ''Drosophila'' (in which they were first discovered) and humans. Hox genes are a subset of the homeobox genes. The Hox genes are often conserved across species, so some of the Hox genes of ''Drosophila'' are homologous to those in humans. In general, Hox genes pl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bithorax Complex
The Bithorax complex (BX-C) is one of two ''Drosophila melanogaster'' homeotic gene complexes, located on the right arm of chromosome 3. It is responsible for the differentiation of the posterior two-thirds (posterior thorax and each abdominal segment) of the fly by the regulation of three genes within the complex: ''Ultrabithorax (Ubx)'''', abdominal A (abd-A),'' and ''Abdominal B (Abd-B)''. A complete deletion of this complex results in the posterior segments of the ''Drosophila'' embryo becoming copies of the second thoracic segment. History The first homeotic mutation to be isolated was the ''bithorax (bx)'' mutant in 1915 by Calvin Bridges, which was later worked on and better characterized as a gene cluster by Edward B. Lewis. Lewis found that BX-C contained genes that code for proteins controlling the levels of thoracic and abdominal development, and postulated that at least four of these genes were regulated by cis-regulatory elements, as well as a separate locus (Pol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ed Lewis 1986
Ed, ed or ED may refer to: Arts and entertainment * ''Ed'' (film), a 1996 film starring Matt LeBlanc * Ed (''Fullmetal Alchemist'') or Edward Elric, a character in ''Fullmetal Alchemist'' media * ''Ed'' (TV series), a TV series that ran from 2000 to 2004 * ED, an abbreviated term for ending theme songs in anime Businesses and organizations * Ed (supermarket), a French brand of discount stores founded in 1978 * Consolidated Edison, from their NYSE stock symbol * United States Department of Education, a department of the United States government * Enforcement Directorate, a law enforcement and economic intelligence agency in India * European Democrats, a loose association of conservative political parties in Europe * Airblue (IATA code ED), a private Pakistani airline * Eagle Dynamics, a Swiss software company Places * Ed, Kentucky, an unincorporated community in the United States * Ed, Sweden, a town in Dals-Ed, Sweden * Erode Junction railway station, in Erode, Tamil N ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
