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Edmond Fischer
Edmond Henri Fischer (April 6, 1920 – August 27, 2021) was a Swiss-American biochemist. He and his collaborator Edwin G. Krebs were awarded the Nobel Prize in Physiology or Medicine in 1992 for describing how reversible phosphorylation works as a switch to activate proteins and regulate various cellular processes. From 2007 until 2014, he was the Honorary President of the World Cultural Council. At the time of his death at age 101 in 2021, he was the oldest living Nobel Prize laureate. Early life Fischer was born on April 6, 1920, in the Shanghai International Settlement, China. His mother, Renée Tapernoux, was born in France, and his father, Oscar Fischer, was born in Austria. His father, who was Jewish, practiced as a lawyer in Shanghai before the various consular courts in the city. Fischer's maternal grandfather founded the ''Courrier de Chine'' in Shanghai, the first newspaper published in French in China; he also helped to establish L'Ecole Municipale Française i ...
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Shanghai International Settlement
The Shanghai International Settlement () originated from the 1863 merger of the British Concession (Shanghai), British and American Concession (Shanghai), American list of former foreign enclaves in China, enclaves in Shanghai, in which British and American citizens would enjoy extraterritoriality and Consular court, consular jurisdiction under the terms of Unequal treaty, unequal treaties agreed by both parties. These treaties were abrogated in 1943. The British settlements were established following the victory of the British Empire, British in the First Opium War (18391842). Under the terms of the Treaty of Nanking, the five treaty ports including Shanghai were opened to foreign merchants, overturning the monopoly then held by the southern port of Canton (Guangzhou) under the Canton System. The British also established a base on British Hong Kong, Hong Kong. American and French involvement followed closely on the heels of the British and their enclaves were established nor ...
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Maternal Grandfather
Grandparents, individually known as grandmother and grandfather, or Grandma and Grandpa, are the parents of a person's father or mother – paternal or maternal. Every sexually reproducing living organism who is not a genetic chimera has a maximum of four genetic grandparents, eight genetic great-grandparents, sixteen genetic great-great-grandparents, thirty-two genetic great-great-great-grandparents, sixty-four genetic great-great-great-great-grandparents, etc. In the history of modern humanity, around 30,000 years ago, the number of modern humans who lived to be a grandparent increased. It is not known for certain what spurred this increase in longevity, but it is generally believed that a key consequence of three generations being alive together was the preservation of information which could otherwise have been lost; an example of this important information might have been where to find water in times of drought. In cases where parents are unwilling or unable to provide ...
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Amylase
An amylase () is an enzyme that catalysis, catalyses the hydrolysis of starch (Latin ') into sugars. Amylase is present in the saliva of humans and some other mammals, where it begins the chemical process of digestion. Foods that contain large amounts of starch but little sugar, such as rice and potatoes, may acquire a slightly sweet taste as they are chewed because amylase degrades some of their starch into sugar. The pancreas and salivary gland make amylase (alpha amylase) to hydrolyse dietary starch into disaccharides and trisaccharides which are converted by other enzymes to glucose to supply the body with energy. Plants and some bacteria also produce amylase. Specific amylase proteins are designated by different Greek letters. All amylases are glycoside hydrolases and act on α-1,4-glycosidic bonds. Classification α-Amylase The α-amylases () (CAS registry number, CAS 9014–71–5) (alternative names: 1,4-α-D-glucan glucanohydrolase; glycogenase) are calcium metallop ...
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Enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecules known as product (chemistry), products. Almost all metabolism, metabolic processes in the cell (biology), cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme, pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts include Ribozyme, catalytic RNA molecules, also called ribozymes. They are sometimes descr ...
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Polysaccharides
Polysaccharides (), or polycarbohydrates, are the most abundant carbohydrates found in food. They are long-chain polymeric carbohydrates composed of monosaccharide units bound together by glycosidic linkages. This carbohydrate can react with water (hydrolysis) using amylase enzymes as catalyst, which produces constituent sugars (monosaccharides or oligosaccharides). They range in structure from linear to highly branched. Examples include storage polysaccharides such as starch, glycogen and galactogen and structural polysaccharides such as hemicellulose and chitin. Polysaccharides are often quite heterogeneous, containing slight modifications of the repeating unit. Depending on the structure, these macromolecules can have distinct properties from their monosaccharide building blocks. They may be amorphous or even insoluble in water. When all the monosaccharides in a polysaccharide are the same type, the polysaccharide is called a homopolysaccharide or homoglycan, but when more t ...
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World War II
World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the world's countries participated, with many nations mobilising all resources in pursuit of total war. Tanks in World War II, Tanks and Air warfare of World War II, aircraft played major roles, enabling the strategic bombing of cities and delivery of the Atomic bombings of Hiroshima and Nagasaki, first and only nuclear weapons ever used in war. World War II is the List of wars by death toll, deadliest conflict in history, causing World War II casualties, the death of 70 to 85 million people, more than half of whom were civilians. Millions died in genocides, including the Holocaust, and by massacres, starvation, and disease. After the Allied victory, Allied-occupied Germany, Germany, Allied-occupied Austria, Austria, Occupation of Japan, Japan, a ...
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Tuberculosis
Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as inactive or latent tuberculosis. A small proportion of latent infections progress to active disease that, if left untreated, can be fatal. Typical symptoms of active TB are chronic cough with hemoptysis, blood-containing sputum, mucus, fever, night sweats, and weight loss. Infection of other organs can cause a wide range of symptoms. Tuberculosis is Human-to-human transmission, spread from one person to the next Airborne disease, through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with latent TB do not spread the disease. A latent infection is more likely to become active in those with weakened I ...
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Louis Pasteur
Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist, pharmacist, and microbiologist renowned for his discoveries of the principles of vaccination, Fermentation, microbial fermentation, and pasteurization, the last of which was named after him. His research in chemistry led to remarkable breakthroughs in the understanding of the causes and preventions of diseases, which laid down the foundations of hygiene, public health and much of modern medicine. Pasteur's works are credited with saving millions of lives through the developments of vaccines for rabies vaccine, rabies and anthrax vaccine, anthrax. He is regarded as one of the founders of modern bacteriology and has been honored as the "father of bacteriology" and the "father of microbiology" (together with Robert Koch; the latter epithet also attributed to Antonie van Leeuwenhoek). Pasteur was responsible for disproving the doctrine of spontaneous generation. Under the auspices of the French Aca ...
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Microbiology
Microbiology () is the branches of science, scientific study of microorganisms, those being of unicellular organism, unicellular (single-celled), multicellular organism, multicellular (consisting of complex cells), or non-cellular life, acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, protistology, mycology, immunology, and parasitology. The organisms that constitute the microbial world are characterized as either prokaryotes or eukaryotes; eukaryote, Eukaryotic microorganisms possess membrane-bound organelles and include fungi and protists, whereas prokaryote, prokaryotic organisms are conventionally classified as lacking membrane-bound organelles and include Bacteria and Archaea. Microbiologists traditionally relied on culture, staining, and microscopy for the isolation and identification of microorganisms. However, less than 1% of the microorganisms present in common environments can be cultured in isolation using c ...
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Conservatoire De Musique De Genève
The Conservatoire de musique de Genève is a music school in Geneva, Switzerland. The Conservatory hosts 2,400 non-professional students. Since 2009, the professional courses have been led by the Geneva University of Music (''Haute école de musique de Genève''). History The school was founded by in 1835. Its current building, designed by Jean-Baptiste Lesueur, dates from 1858. This conservatory is the oldest music education institution in Switzerland, and one of the oldest conservatories in Europe. Franz Liszt taught at this conservatory during the first year of its history. The Geneva International Music Competition was founded in 1939 in the Conservatory, and is its first international competition. Directors * Nathan Bloc (1835—1849) * Jules Delacour (1849—1859) * Ami Girard (1859—1892) * Ferdinand Held (1892—1925) * Henri Gagnebin (1925—1957) * Samuel Baud-Bovy (1957—1970) * Claude Viala (1970—1992) * Philippe Dinkel (1992—2021) * Béatric ...
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Vevey
Vevey (; ; ) is a town in Switzerland in the Vaud, canton of Vaud, on the north shore of Lake Leman, near Lausanne. The German name Vivis is no longer commonly used. It was the seat of the Vevey (district), district of the same name until 2006, and is now part of the Riviera-Pays-d'Enhaut District. It is part of the French-speaking area of Switzerland. Vevey is home to the world headquarters of the international food and beverage company Nestlé, founded here in 1867. Milk chocolate was invented in Vevey by Daniel Peter in 1875, with the aid of Henri Nestlé. The English actor and comedian Charlie Chaplin resided in Vevey from 1952 until his death in 1977. History A piloti settlement existed here as early as the 2nd millennium BC. Under ancient Rome, Rome, it was known as Viviscus or ''Vibiscum''. It was mentioned for the first time by the ancient Greek astronomer and philosopher Ptolemy, who gave it the name Ouikos. In the Middle Ages it was a station on the Via Francigena ...
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La Châtaigneraie (school)
La Châtaigneraie (also called La Chât) is a private, international, coeducational day school. It is part of the Foundation of the International School of Geneva and offers a comprehensive education in English or French for students from age 4 to 18. Founded in 1908, La Châtaigneraie is located in Founex, Switzerland. History École Nouvelle La Châtaigneraie In 1908, Ernest Schwartz-Buys founded the Ecole Nouvelle du Léman, a coeducational school to be based upon German and English institutions. It opened its doors to girls and boys between 7 and 18 years of age, with a probable enrollment of six students in the 1908–09 school year. Le Collège Protestant Romand (1954–71) In the aftermath of the Second World War, between c. 1948–49, a group of pedagogues and pastors, led by the pastor Charles Bergier, decided that the Lake Geneva area needed a Protestant school. The official request for the establishment of such a school was filed on 10 April 1953 at the Office of E ...
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