EPCR Challenge Cup Seasons

	EPCR Challenge Cup Seasons EPCR may refer to: * Endothelial protein C receptor, a protein encoded by the PROCR gene * ePCR (electronic polymerase chain reaction), or in silico PCR, use of software tools to calculate PCR results * European Professional Club Rugby, organises rugby union club championships {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Endothelial Protein C Receptor Endothelial protein C receptor (EPCR) also known as activated protein C receptor (APC receptor) is a protein that in humans is encoded by the ''PROCR'' gene. PROCR has also recently been designated CD201 (cluster of differentiation 201). EPCR is a transmembrane glycoprotein receptor that plays a crucial role in regulation of blood coagulation, inflammation, and vascular integrity. Its ability to enhance the anticoagulant activity of protein C, modulate inflammatory responses, and maintain endothelial barrier function highlights its importance in homeostasis maintenance. Structure EPCR protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. It belongs to the MHC class I MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of vertebrates. They also occur on .../ CD1 family of prote ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	In Silico PCR In silico PCR refers to computational tools used to calculate theoretical polymerase chain reaction (PCR) results using a given set of primers ( probes) to amplify DNA sequences from a sequenced genome or transcriptome. These tools are used to optimize the design of primers for target DNA or cDNA sequences. Primer optimization has two goals: efficiency and selectivity. Efficiency involves taking into account such factors as GC-content, efficiency of binding, complementarity, secondary structure, and annealing and melting point (Tm). Primer selectivity requires that the primer pairs not fortuitously bind to random sites other than the target of interest, nor should the primer pairs bind to conserved regions of a gene family. If the selectivity is poor, a set of primers will amplify multiple products besides the target of interest. The design of appropriate short or long primer pairs is only one goal of PCR product prediction. Other information provided by ''in silico'' PCR to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]