EHD2
EH-domain containing 2, also known as EHD2, is a human gene belonging to the EHD protein family The EHD protein family is a relatively small group of proteins which have been shown to play a role in several physiological functions, the most notable being the regulation of endocytosis, endocytotic vesicles. This family is recognized by its high .... References Further reading * * * * * * * * * * * External links * EH-domain-containing proteins {{gene-19-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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EHD Protein Family
The EHD protein family is a relatively small group of proteins which have been shown to play a role in several physiological functions, the most notable being the regulation of endocytosis, endocytotic vesicles. This family is recognized by its highly conserved EH (EPS15, Eps15 homology) domain, a structural motif that has been shown to facilitate specificity and interaction between protein and ligand. The four mammalian EHD proteins that have been classified are: EHD1, EHD2, EHD3, and EHD4. History During the late 20th century, several advances were made regarding the identification of proteins involved in endocytotic recycling and other mechanisms of intracellular trafficking. This period of research led to the discovery of over 60 proteins which collectively make up the Rab family. Rab (G-protein), Rab proteins have been found to play a major role in endocytotic recycling via SNARE (protein), SNARE-based vesicle fusion and transport. When bound to GTP, Rab proteins have a large ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |