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EC 6.1
This list contains a list of Enzyme Commission number, EC numbers for the sixth group, EC 6, ligases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee. The database is developed and maintained by Andrew McDonald. EC 6.1: Forming Carbon-Oxygen Bonds EC 6.1.1: Ligases Forming Aminoacyl-tRNA and Related Compounds (Aminoacyl tRNA synthetase) * : tyrosine-tRNA ligase, tyrosine—tRNA ligase * : tryptophan-tRNA ligase, tryptophan—tRNA ligase * : threonine-tRNA ligase, threonine—tRNA ligase * : leucine-tRNA ligase, leucine—tRNA ligase * : isoleucine-tRNA ligase, isoleucine—tRNA ligase * : lysine-tRNA ligase, lysine—tRNA ligase * : alanine-tRNA ligase, alanine—tRNA ligase * : Deleted * : valine-tRNA ligase, valine—tRNA ligase * : methionine-tRNA ligase, methionine—tRNA ligase * : serine-tRNA ligase, serine—tRNA lig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme Commission Number
The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. As a system of enzyme nomenclature, every EC number is associated with a recommended name for the corresponding enzyme-catalyzed reaction. EC numbers do not specify enzymes but enzyme-catalyzed reactions. If different enzymes (for instance from different organisms) catalyze the same reaction, then they receive the same EC number. Furthermore, through convergent evolution, completely different protein folds can catalyze an identical reaction (these are sometimes called non-homologous isofunctional enzymes) and therefore would be assigned the same EC number. By contrast, UniProt identifiers uniquely specify a protein by its amino acid sequence. Format of number Every enzyme code consists of the letters "EC" followed by four numbers separated by periods. Those numbers represent a progressively finer classification of the enzyme. Preliminary ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acetate-CoA Ligase
Acetyl-CoA synthetase (ACS), also commonly known as Acetate—CoA ligase or acetyl activating enzyme, is an enzyme () of the ligase class of enzymes which catalyze the formation of new chemical bonds between two molecules. As such, it is involved in a wide range of biochemical pathways across both Prokaryote, prokaryotic and Eukaryote, eukaryotic organisms, the latter of which rely on it as their only route for acetate activation. Reaction The two molecules joined that make up acetyl-CoA are acetate and coenzyme A (CoA). The complete reaction with all the substrates and products included is: :Adenosine triphosphate, ATP + Acetate + CoA Adenosine monophosphate, AMP + Pyrophosphate + Acetyl-CoA Once acetyl-CoA is formed it can be used in the TCA cycle in aerobic respiration to produce energy and electron carriers. This is an alternate method to starting the cycle, as the more common way is producing acetyl-CoA from pyruvate through the pyruvate dehydrogenase complex. The enzyme's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
D-alanine—(R)-lactate Ligase
D-alanine—(''R'')-lactate ligase (, ''VanA'', ''VanB'', ''VanD'') is an enzyme with systematic name ''D-alanine:(R)-lactate ligase (ADP-forming)''. This enzyme catalyses the following chemical reaction : D-alanine + (R)- lactate + ATP \rightleftharpoons D-alanyl-(R)-lactate + ADP + phosphate Phosphates are the naturally occurring form of the element phosphorus. In chemistry, a phosphate is an anion, salt, functional group or ester derived from a phosphoric acid. It most commonly means orthophosphate, a derivative of orthop ... The product of this enzyme can be incorporated into the peptidoglycan pentapeptide instead of the usual D-alanyl-D-alanine dipeptide. References External links * EC 6.1.2 {{Enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
O-phospho-L-serine—tRNA Ligase
O-phospho-L-serine—tRNA ligase (, ''O-phosphoseryl-tRNA ligase'', ''non-canonical O-phosphoseryl-tRNA synthetase'', ''SepRS'') is an enzyme with systematic name ''O-phospho-L-serine:tRNACys ligase (AMP-forming)''. This enzyme catalyses the following chemical reaction: : ATP + O-phospho-L-serine + tRNACys \rightleftharpoons AMP + diphosphate + O-phospho-L-seryl-tRNACys In organisms like ''Archaeoglobus fulgidus ''Archaeoglobus'' is a genus of archaeans in the phylum Euryarchaeota. ''Archaeoglobus'' can be found in high-temperature oil fields where they may contribute to oil field souring. Metabolism ''Archaeoglobus'' grow anaerobically at extremely ...'', this enzyme ligates O-phosphoserine to tRNACys. References External links * {{DEFAULTSORT:O-phospho-L-serine-tRNA ligase EC 6.1.1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pyrrolysine—tRNAPyl Ligase
Pyrrolysine—tRNAPyl ligase (, ''PylS'', ''pyrrolysyl-tRNA synthetase'') is an enzyme with systematic name ''L-pyrrolysine:tRNAPyl ligase (AMP-forming)''. This enzyme catalyses the following chemical reaction : ATP + L-pyrrolysine + tRNAPyl \rightleftharpoons AMP + diphosphate + L-pyrrolysyl-tRNAPyl This enzyme is specific for pyrrolysine as substrate as it cannot be replaced by lysine Lysine (symbol Lys or K) is an α-amino acid that is a precursor to many proteins. Lysine contains an α-amino group (which is in the protonated form when the lysine is dissolved in water at physiological pH), an α-carboxylic acid group ( ... or any of the other natural amino acids. References External links * {{DEFAULTSORT:Pyrrolysine-tRNAPyl ligase EC 6.1.1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
