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Décrypthon
Décrypthon is a project which uses grid computing resources to contribute to medical research. The word is a portmanteau of the French word "décrypter" (to decipher) and "telethon". Description Décrypthon is a technology platform providing the computational power required to process complex data in biology. It allows, through technologies called " grids", to gather (in a grid) the capacity of several supercomputers (500 Gflop) installed by IBM in 6 French universities (Bordeaux 1, Lille 1, Paris 6 Jussieu, ENS Lyon, Crihan in Rouen, Orsay) and/or individual personal computers via the World Community Grid, itself a BOINC project. A dozen scientific projects selected through a call for tenders have been completed under the Décrypthon program. History During the 2001 French Telethon, the AFM ("Association française contre les myopathies" / "French Association Against Myopathy") and IBM launched a call to mobilize Internet users: "Make your unused computer time available to r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Community Grid
World Community Grid (WCG) is an effort to create the world's largest volunteer computing platform to perform scientific research that benefits humanity. Launched on November 16, 2004, with proprietary Grid MP client from United Devices and adding support for Berkeley Open Infrastructure for Network Computing (BOINC) in 2005, World Community Grid eventually discontinued the Grid MP client and consolidated on the BOINC platform in 2008. In September 2021, it was announced that IBM transferred ownership to the Krembil Research Institute of University Health Network in Toronto, Ontario. World Community Grid uses unused processing power of consumer devices (PCs, Laptops, Android Smartphones, etc.) to analyse data created by the research groups that participate in the grid. WCG projects have analysed data related to the human genome, the human microbiome, HIV, dengue, muscular dystrophy, cancer, influenza, Ebola, Zika virus, virtual screening, rice crop yields, clean energy, wat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
English Language
English is a West Germanic language that developed in early medieval England and has since become a English as a lingua franca, global lingua franca. The namesake of the language is the Angles (tribe), Angles, one of the Germanic peoples that Anglo-Saxon settlement of Britain, migrated to Britain after its End of Roman rule in Britain, Roman occupiers left. English is the list of languages by total number of speakers, most spoken language in the world, primarily due to the global influences of the former British Empire (succeeded by the Commonwealth of Nations) and the United States. English is the list of languages by number of native speakers, third-most spoken native language, after Mandarin Chinese and Spanish language, Spanish; it is also the most widely learned second language in the world, with more second-language speakers than native speakers. English is either the official language or one of the official languages in list of countries and territories where English ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peroxisome
A peroxisome () is a membrane-bound organelle, a type of microbody, found in the cytoplasm of virtually all eukaryotic cells. Peroxisomes are oxidative organelles. Frequently, molecular oxygen serves as a co-substrate, from which hydrogen peroxide (H2O2) is then formed. Peroxisomes owe their name to hydrogen peroxide-generating and scavenging activities. They perform key roles in lipid metabolism and the redox, reduction of reactive oxygen species. Peroxisomes are involved in the catabolism of very long chain fatty acids, branched chain fatty acids, bile acid intermediates (in the liver), D-amino acids, and polyamines. Peroxisomes also play a role in the biosynthesis of plasmalogens: ether phospholipids critical for the normal function of mammalian brains and lungs. Peroxisomes contain approximately 10% of the total activity of two enzymes (Glucose-6-phosphate dehydrogenase and Phosphogluconate dehydrogenase, 6-Phosphogluconate dehydrogenase) in the pentose phosphate pathway, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
USTL
U.S. Term Limits (USTL) is a non-profit, non-partisan grassroots organization dedicated to enacting term limits for elected officials at every level of government in the United States. It was founded in 1992, and says it has helped facilitate more than 500 successful term limits initiatives at various levels of government. Among other activities, USTL supports statewide ballot initiatives to impose term limits. In the early 1990s, USTL organized grassroots campaigns that placed term limits on the congressional delegations of 23 states. These were overturned as unconstitutional in 1995 by the Supreme Court In most legal jurisdictions, a supreme court, also known as a court of last resort, apex court, high (or final) court of appeal, and court of final appeal, is the highest court within the hierarchy of courts. Broadly speaking, the decisions of ..., in a 5–4 decision in '' U.S. Term Limits v. Thornton''. U.S. Term Limits is promoting a convention to propose amendments u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laboratoire D'Informatique Fondamentale De Lille
The Laboratoire d'Informatique Fondamentale de Lille (LIFL), is a computer science research laboratory of University of Lille, in Lille, France. LIFL was founded in 1983 and currently employs more than 200 employees. Since January 2015, the LIFL has merged with another laboratory, the Laboratoire d'Automatique, Génie Informatique et Signal (LAGIS). The resulting laboratory is now CRIStAL. Most of the projects and teams at LIFL are supported and funded by the French National Centre for Scientific Research (CNRS) and the French National Institute for Research in Computer Science and Control The National Institute for Research in Digital Science and Technology (Inria) () is a French national research institution focusing on computer science and applied mathematics. It was created under the name French Institute for Research in Comp ... (INRIA). ReferencesLIFL [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genome
A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of junk DNA with no evident function. Almost all eukaryotes have mitochondrial DNA, mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplast DNA, chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been Whole-genome sequencing, sequenced and various regions have been annotated. The first genome to be sequenced was that of the virus φX174 in 1977; the first genome sequence of a prokaryote (''Haemophilus influenzae'') was published in 1995; the yeast (''Saccharomyces cerevisiae'') genome was the first eukaryotic genome to be sequenced in 1996. The Human Genome Project ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular and cellular studies of individual neurons to imaging of sensory, motor and cognitive tasks in the brain. Hist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monte Carlo Method
Monte Carlo methods, or Monte Carlo experiments, are a broad class of computational algorithms that rely on repeated random sampling to obtain numerical results. The underlying concept is to use randomness to solve problems that might be deterministic in principle. The name comes from the Monte Carlo Casino in Monaco, where the primary developer of the method, mathematician Stanisław Ulam, was inspired by his uncle's gambling habits. Monte Carlo methods are mainly used in three distinct problem classes: optimization, numerical integration, and generating draws from a probability distribution. They can also be used to model phenomena with significant uncertainty in inputs, such as calculating the risk of a nuclear power plant failure. Monte Carlo methods are often implemented using computer simulations, and they can provide approximate solutions to problems that are otherwise intractable or too complex to analyze mathematically. Monte Carlo methods are widely used in va ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Université René Descartes
Paris Descartes University (), also known as Paris V, was a French public university located in Paris. It was one of the inheritors of the historic University of Paris, which was split into 13 universities in 1970. Paris Descartes completely merged with Paris Diderot University in 2019 to form a new Paris Cité University. It was established as a multidisciplinary university "of humanities and health sciences" ("''des Sciences de l’Homme et de la Santé''". It focused on the areas of medical sciences, biomedical sciences, law, computer science, social sciences, economics and psychology. Its main campus was in the historic École de Chirurgie in the 6th arrondissement of Paris. History The historic University of Paris () first appeared in the second half of the 12th century, but was divided into thirteen universities, managed by a common rectorate, the Chancellerie des Universités de Paris, after the student protests of the French May. Administration Campus Descartes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ligands
In coordination chemistry, a ligand is an ion or molecule with a functional group that binds to a central metal atom to form a coordination complex. The bonding with the metal generally involves formal donation of one or more of the ligand's electron pairs, often through Lewis bases. The nature of metal–ligand bonding can range from covalent to ionic. Furthermore, the metal–ligand bond order can range from one to three. Ligands are viewed as Lewis bases, although rare cases are known to involve Lewis acidic "ligands". Metals and metalloids are bound to ligands in almost all circumstances, although gaseous "naked" metal ions can be generated in a high vacuum. Ligands in a complex dictate the reactivity of the central atom, including ligand substitution rates, the reactivity of the ligands themselves, and redox. Ligand selection requires critical consideration in many practical areas, including bioinorganic and medicinal chemistry, homogeneous catalysis, and environme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Université Pierre Et Marie Curie
Pierre and Marie Curie University ( , UPMC), also known as Paris VI, was a public research university in Paris, France, from 1971 to 2017. The university was located on the Jussieu Campus in the Latin Quarter of the 5th arrondissement of Paris, France. UPMC merged with Paris-Sorbonne University into a new combined Sorbonne University. History Paris VI was one of the inheritors of the faculty of Sciences of the University of Paris, which was divided into several universities in 1970 after the student protests of May 1968. In 1971, the five faculties of the former University of Paris (Paris VI as the Faculty of Sciences) were split and then re-formed into thirteen universities by the Faure Law. The campus of Paris VI was built in the 1950s and 1960s, on a site previously occupied by wine storehouses. The Dean, Marc Zamanski, saw the Jussieu campus standing as a tangible symbol of scientific thought in the heart of Paris, with the Faculty of Science, set in the Latin Quarter, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inserm
The (Inserm, ) is the French National Institute of Health and Medical Research. History and organisation Inserm was created in 1964 as a successor to the French National Institute of Health. Inserm is the only public research institution solely focused on human health and medical research in France. It is a public institution with a scientific and technical vocation under the dual auspices of the Ministry of Health and the Ministry of Research. Similarly to the US National Institutes of Health, Inserm conducts fundamental and translational research projects through 339 research units, run by around 13,000 scientists, including 5,100 permanent research staff members and 5,100 staff members co-affiliated with university hospitals and medicine faculties. Inserm's laboratories and research units are located all over France, mainly in the largest cities. Eighty percent of Inserm research units are embedded in research hospitals of French universities. In 1997, Inserm founded ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
