Donafenib
Donafenib, sold under the brand name Zepsun, is a pharmaceutical drug for the treatment of cancer. In China, donafenib is approved for the treatment of unresectable hepatocellular carcinoma in patients who have not previously received systemic treatment. Donafenib is a kinase inhibitor that targets Raf kinase and various receptor tyrosine kinases. It is a deuterated derivative of sorafenib with improved pharmacokinetic Pharmacokinetics (from Ancient Greek ''pharmakon'' "drug" and ''kinetikos'' "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific subs ... properties. References {{reflist Receptor tyrosine kinase inhibitors Chloroarenes Trifluoromethyl compounds Ureas Phenol ethers Disubstituted pyridines Benzamides Diaryl ethers Deuterated compounds ...
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