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Dihydropteridine-hydroxymethyl-pyrophosphate
2-Amino-4-hydroxy-6-pyrophosphoryl-methylpteridine (7,8-Dihydropterin pyrophosphate, dihydropterin-CH2OH-diphosphate) is a pteridine; a precursor to dihydrofolic acid Dihydrofolic acid (conjugate base dihydrofolate) (DHF) is a folic acid ( vitamin B9) derivative which is converted to tetrahydrofolic acid by dihydrofolate reductase. Since tetrahydrofolate is needed to make both purines and pyrimidines, which ar .... References Pteridines {{Biochem-stub ...
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Pteridine
Pteridine is an aromatic chemical compound composed of fused pyrimidine and pyrazine rings. A pteridine is also a group of heterocyclic compounds containing a wide variety of substitutions on this structure. Pterins and flavins are classes of substituted pteridines that have diverse biological roles. See also * Dihydrobiopterin * Pyrazine * Pyrimidine Pyrimidine (; ) is an aromatic, heterocyclic, organic compound similar to pyridine (). One of the three diazines (six-membered heterocyclics with two nitrogen atoms in the ring), it has nitrogen atoms at positions 1 and 3 in the ring. The othe ... * Tetrahydrobiopterin References {{heterocyclic-stub ...
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Dihydrofolic Acid
Dihydrofolic acid (conjugate base dihydrofolate) (DHF) is a folic acid ( vitamin B9) derivative which is converted to tetrahydrofolic acid by dihydrofolate reductase. Since tetrahydrofolate is needed to make both purines and pyrimidines, which are building blocks of DNA and RNA, dihydrofolate reductase is targeted by various drugs to prevent nucleic acid Nucleic acids are biopolymers, macromolecules, essential to all known forms of life. They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous base. The two main ... synthesis. Interactive pathway map Further reading * References Folates {{organic-compound-stub ...
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