Diana Prata
Diana Prata is a Portuguese neuroscientist who concentrates on identifying the biological basis of human behaviour. She reported the first evidence that schizophrenia-risk genes can also predispose to bipolar disorder and has also investigated reasons why people respond differently to antipsychotic medications. She is head of the Biomedical Neuroscience Lab at the University of Lisbon. Training Diana Prata studied at secondary school in Almada, Portugal on the left bank of the River Tagus, to the southwest of the Portuguese capital of Lisbon. Between 1997 and 2002, she studied for a BSc and an MSc in biology at the University of Lisbon, obtaining an Erasmus scholarship for study in Crete. With the help of a Leonardo da Vinci programme fellowship she moved to the Institute of Psychiatry, Psychology and Neuroscience at King's College London (KCL) and then obtained a grant from the Portuguese ''Fundação para a Ciência e Tecnologia'' (Science and Technology Foundation -FCT) to com ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Portugal
Portugal, officially the Portuguese Republic, is a country on the Iberian Peninsula in Southwestern Europe. Featuring Cabo da Roca, the westernmost point in continental Europe, Portugal borders Spain to its north and east, with which it shares Portugal-Spain border, the longest uninterrupted border in the European Union; to the south and the west is the North Atlantic Ocean; and to the west and southwest lie the Macaronesia, Macaronesian archipelagos of the Azores and Madeira, which are the two Autonomous Regions of Portugal, autonomous regions of Portugal. Lisbon is the Capital city, capital and List of largest cities in Portugal, largest city, followed by Porto, which is the only other Metropolitan areas in Portugal, metropolitan area. The western Iberian Peninsula has been continuously inhabited since Prehistoric Iberia, prehistoric times, with the earliest signs of Human settlement, settlement dating to 5500 BC. Celts, Celtic and List of the Pre-Roman peoples of the Iberia ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Biomarker (medicine)
In medicine, a biomarker is a measurable wikt:indicator, indicator of the severity or presence of some disease state. It may be defined as a "cellular, biochemical or molecular alteration in cells, tissues or fluids that can be measured and evaluated to indicate normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention." More generally a biomarker is anything that can be used as an indicator of a particular disease state or some other physiological state of an organism. According to the WHO, the indicator may be chemical, physical, or biological in nature - and the measurement may be functional, physiological, biochemical, cellular, or molecular. A biomarker can be a substance that is introduced into an organism as a means to examine organ function or other aspects of health. For example, rubidium chloride is used in isotopic labeling to evaluate perfusion of heart muscle. It can also be a substance whose detection indicates a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Radio France Internationale
Radio France Internationale, usually referred to as RFI, is the State media, state-owned international radio news network of France. With 59.5 million listeners in 2022, it is one of the most-listened-to international radio stations in the world, along with Deutsche Welle, the BBC World Service and Voice of America. RFI broadcasts 24 hours per day around the world in French and in 16 other languages in FM, shortwave, medium wave, satellite and on its website. It is a channel of the state company France Médias Monde. The majority of shortwave transmissions are in French and Hausa language, Hausa but also includes some hours of Swahili language, Swahili, Fulfulde language, Fulfulde and Mandinka language, Mandinka. RFI broadcasts to over 150 countries on 5 continents. Africa is the largest part of radio listeners, representing 60% of the total audience in 2010. In the Île-de-France, Paris region, RFI comprises between 150,000 and 200,000 listeners. Its digital platforms attract an ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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History (European TV Channel)
History (known as Sky History in the UK and Ireland) is a European Documentary film, documentary television channel which broadcasts programs related to History, historical events and persons. There are also reality television, ufology and paranormal programs. It is a joint venture between A&E Networks, Hearst Networks UK and Sky Group with localized channels across Europe. TVT Media is responsible for signal distribution in Europe, with local subsidiaries of A&E Networks as distribution representatives on the continent. Programming across the channels is primarily in English and where available Subtitle (captioning), subtitled or Dubbing (filmmaking), dubbed into regional languages. The channel is available through a number of satellite, cable, terrestrial and IPTV distributors across Europe, the Middle East and South Africa. In some countries, advertisements and announcements between programs are localized. On 6 November 2018, in the wake of the Acquisition of 21st Century ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become more prevalent as the disease progresses. The motor symptoms are collectively called parkinsonism and include tremors, bradykinesia, spasticity, rigidity as well as postural instability (i.e., difficulty maintaining balance). Non-motor symptoms develop later in the disease and include behavior change (individual), behavioral changes or mental disorder, neuropsychiatric problems such as sleep abnormalities, psychosis, anosmia, and mood swings. Most Parkinson's disease cases are idiopathic disease, idiopathic, though contributing factors have been identified. Pathophysiology involves progressive nerve cell death, degeneration of nerve cells in the substantia nigra, a midbrain region that provides dopamine to the basal ganglia, a system invo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the average life expectancy following diagnosis is three to twelve years. The causes of Alzheimer's disease remain poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of apolipoprotein E. Other risk factors include a history of head injury, clinical depression, and high blood pressure. The progression of the di ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Prognosis
Prognosis ( Greek: πρόγνωσις "fore-knowing, foreseeing"; : prognoses) is a medical term for predicting the likelihood or expected development of a disease, including whether the signs and symptoms will improve or worsen (and how quickly) or remain stable over time; expectations of quality of life, such as the ability to carry out daily activities; the potential for complications and associated health issues; and the likelihood of survival (including life expectancy). A prognosis is made on the basis of the normal course of the diagnosed disease, the individual's physical and mental condition, the available treatments, and additional factors. A complete prognosis includes the expected duration, function, and description of the course of the disease, such as progressive decline, intermittent crisis, or sudden, unpredictable crisis. When applied to large statistical populations, prognostic estimates can be very accurate: for example the statement "45% of patients with sever ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Oxytoxin
Oxotoxins, or oxytoxins, are a group of neurotoxins present in the venom of lynx spiders belonging to the genus ''Oxyopes'', hence the name ''oxytoxin''. They are disulfide-rich peptides. Only two types are so far reported from two different species, the larger oxytoxin 1 (OxyTx1) from '' Oxyopes kitabensis'', and the smaller oxytoxin 2 (OxyTx2) from '' Oxyopes lineatus''. OxyTx1, the first known oxytoxin, was discovered in 2002. It was found to enhance the lethal efficacy of the spider venom by acting together with oxyopinins. It is composed of 69 amino acid residue, which are cross-linked by five disulfide bridges. It is a large peptide having a molecular mass of 8059.2 Da; but shows the size of 9,109.4 Da due to the presence of disulfide bridges. It is a potent insecticide, but non-toxic to mice up to 1 μg/20-g mouse. It acts synergistically with oxyopinins of the same venom to increase the insecticidal effect. Both OxyTx1 and OxyTx2 were isolated in 2008 from ''O. lineatu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Psychophysiological
Psychophysiology (from Greek , ''psȳkhē'', "breath, life, soul"; , ''physis'', "nature, origin"; and , ''-logia'') is the branch of psychology that is concerned with the physiological bases of psychological processes. While psychophysiology was a general, broad field of research in the 1960s and 1970s, it has now become quite specialized, based on methods, topic of studies, and scientific traditions. Methods vary as combinations of electrophysiological methods (such as EEG), neuroimaging (MRI, PET), and neurochemistry. Topics have branched into subspecializations such as social, sport, cognitive, cardiovascular, clinical, and other branches of psychophysiology. Background Some people have difficulty distinguishing a psychophysiologist from a physiological psychologist, which has two very different perspectives. Psychologists are interested in why we may fear spiders and physiologists may be interested in the input/output system of the amygdala. A psychophysiologist will ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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White Matter
White matter refers to areas of the central nervous system that are mainly made up of myelinated axons, also called Nerve tract, tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution of action potentials, acting as a relay and coordinating communication between different brain regions. White matter is named for its relatively light appearance resulting from the lipid content of myelin. Its white color in prepared specimens is due to its usual preservation in formaldehyde. It appears pinkish-white to the naked eye otherwise, because myelin is composed largely of lipid tissue veined with capillaries. Structure White matter White matter is composed of bundles, which connect various grey matter areas (the locations of nerve cell bodies) of the brain to each other, and carry nerve impulses between neurons. Myelin acts as an insulator, which allows saltatory conduction, electrical signals to jump, rather than cour ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bial
Kempegowda International Airport is an international airport serving Bengaluru, the capital of the Indian state of Karnataka. Spread over , it is located about north of the city near the suburb of Devanahalli. It is owned and operated by Bengaluru International Airport Limited (BIAL), a public–private consortium. The airport opened in May 2008 as an alternative to the increasingly congested HAL Airport, the original commercial airport serving the city. It is named after Kempe Gowda I, the founder of Bengaluru. Kempegowda International Airport became Karnataka's first fully solar powered airport, developed by CleanMax Solar. The airport is the third-busiest in India, behind the airports in Delhi and Mumbai. It is the 26th busiest airport in Asia and the 54th busiest airport in the world as of 2024. In FY2024-25, the airport handled over 41.87 million passengers and of cargo. The airport offers connecting flights to all six inhabited continents, and direct flights to ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |