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Deprescribing
Deprescribing is a process of tapering or stopping medications to achieve improved health outcomes by reducing exposure to medications that are potentially either harmful or no longer required. Deprescribing is important to consider with changing health and care goals over time, as well as polypharmacy and adverse effects. Deprescribing can improve adherence, cost, and health outcomes but may have adverse drug withdrawal effects. More specifically, deprescribing is the planned and supervised process of intentionally stopping a medication or reducing its dose to improve the person's health or reduce the risk of adverse side effects. Deprescribing is usually done because the drug may be causing harm, may no longer be helping the patient, or may be inappropriate for the individual patient's current situation. Deprescribing can help correct polypharmacy and prescription cascade. Deprescribing is often done with people who have multiple long-term conditions (multimorbidity), older ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polypharmacy
Polypharmacy (polypragmasia) is an umbrella term to describe the simultaneous use of multiple medicines by a patient for their conditions. The term polypharmacy is often defined as regularly taking five or more medicines but there is no standard definition and the term has also been used in the context of when a person is prescribed 2 or more medications at the same time. Polypharmacy may be the consequence of having multiple long-term conditions, also known as multimorbidity and is more common in the elderly. In some cases, an excessive number of medications at the same time is worrisome, especially for people who are older with many chronic health conditions, because this increases the risk of an adverse event in that population. In many cases, polypharmacy cannot be avoided, but 'appropriate polypharmacy' practices are encouraged to decrease the risk of adverse effects. Appropriate polypharmacy is defined as the practice of prescribing for a person who has multiple conditions or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maudsley Deprescribing Guidelines
The ''Maudsley Prescribing Guidelines'' (also known by the abbreviation MPG) is a referenced prescribing guideline for psychotropic drugs. History of publication Originally the MPG was produced for local readership in Bethlem Royal Hospital and Maudsley Hospital in London.''Toone B The Bethlem and Maudsley NHS Trust Prescribing Guidelines 1999'', J Neurol Neurosurg Psychiatry, 68, London, 2000, p. 125 The 5th edition was the first to be published commercially in 1999 by Martin Dunitz. The 6th (2001) and 7th (2003) were also published by Martin Dunitz. In 2004, Martin Dunitz were subsumed into Taylor and Francis Group and the 8th edition was published under this imprint in 2005. Taylor and Francis then became part of Informa Healthcare who published the 9th edition in 2007 and the 10th edition in 2009. The MPG is revised every two years or so and the 11th edition was published in 2011 by Wiley Blackwell. The 12th edition was published on 17 April 2015 and is available in paperb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medication Appropriateness Tool For Comorbid Health Conditions During Dementia
The Medication Appropriateness Tool for Comorbid Health conditions during Dementia (MATCH-D) criteria supports clinicians to manage medication use specifically for people with dementia without focusing only on the management of the dementia itself. History The MATCH-D were developed by medical practitioners and pharmacists at Australian Group of Eight Universities. It was led by Dr Amy Page at the Western Australian Centre for Health and Ageing at the University of Western Australia. The MATCH-D Criteria were developed through a consensus panel of experts using the Delphi method. The criteria were originally published in the Internal Medicine Journal in 2016. The protocol explaining the rigorous methods used to develop the criteria were originally published in the BMJ Open in 2015. The systematic review that informed the criteria were published subsequently in 2018 and updated in 2022. Style of the criteria The MATCH-D is presented in categories of recommendations for all st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Interaction
In pharmaceutical sciences, drug interactions occur when a drug's mechanism of action is affected by the concomitant administration of substances such as foods, beverages, or other drugs. A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs. Interactions may occur by simultaneous targeting of receptors, directly or indirectly. For example, both Zolpidem and alcohol affect GABAA receptors, and their simultaneous consumption results in the overstimulation of the receptor, which can lead to loss of consciousness. When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. Drug interactions can be of three kinds: * additive (the result is what you expect when you add together the effect of each drug take ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medication
Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to medical diagnosis, diagnose, cure, treat, or preventive medicine, prevent disease. Drug therapy (pharmacotherapy) is an important part of the medicine, medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are Drug class, classified in many ways. One of the key divisions is by level of controlled substance, control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the medical prescription) from over-the-counter drugs (those that consumers can order for themselves). Medicines may be classified by mode of action, route of administration, biological system affected, or therapeutic effects. The World Health Organization keeps a list of essential medicines. Drug discovery and drug development are complex and expensive endeavors undertake ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Multimorbidity
Multimorbidity, also known as multiple long-term conditions (MLTC), means living with two or more chronic illnesses. For example, a person could have diabetes, heart disease and Depression (mood), depression at the same time. Multimorbidity can have a significant impact on people's health and wellbeing. It also poses a complex challenge to Health system, healthcare systems which are traditionally focused on individual diseases. Multiple long-term conditions can affect people of any age, but they are more common in older age, affecting more than half of people over 65 years old. Definition The concept of multiple long-term conditions is not clearly defined and may be referred to by various names. Difference from comorbidity Multimorbidity is often referred to as comorbidity even though the two are considered distinct clinical scenarios. Comorbidity means that one 'index' condition is the focus of attention, and others are viewed in relation to this. In contrast, multimorbidit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medication Discontinuation
Medication discontinuation is the ceasing of a medication treatment for a patient by either the clinician or the patient themself. When initiated by the clinician, it is known as deprescribing. Medication discontinuation is an important medical practice that may be motivated by a number of reasons: * Reducing polypharmacy * Reducing health expenditure * Improving quality of life by ceasing medications with potential adverse effects or where the indication for a medical treatment may have changed * Reflect changes in evidence that support a treatment * Reflecting changes in treatment goals, such as a move to end-of-life care. Unlike the prescribing of medications, appropriate discontinuation has not attracted nearly as much attention or interest. End-of-life care Medications may be stopped in the context of end-of-life care, such as medications that may affect risk factors for future disease. Medications that may be stopped as part of discussions about end-of-life care include ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Long-term Care
Long-term care (LTC) is a variety of services which help meet both the medical and non-medical needs of people with a chronic illness or disability who cannot care for themselves for long periods. Long-term care is focused on individualized and coordinated services that promote independence, maximize patients' quality of life, and meet patients' needs over a period of time. It is common for long-term care to provide custodial and non-skilled care, such as assisting with activities of daily living like dressing, feeding, using the bathroom, meal preparation, functional transfers and safe restroom use. Increasingly, long-term care involves providing a level of medical care that requires the expertise of skilled practitioners to address the multiple long-term conditions associated with older populations. Long-term care can be provided at home, in the community, in assisted living facilities or in nursing homes. Long-term care may be needed by people of any age, although it is a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Overmedication
Overmedication describes the excessive use of over-the-counter or prescription medicines for a person. Overmedication can have harmful effects, such as non-adherence or interactions with multiple prescription drugs. Over-the-counter medication overuse Over-the-counter (OTC) medications are generally first-line therapies that people may choose to treat common acute illnesses, such as fevers, colds, allergies, headaches, or other pain. Many of these medications can be bought in retail pharmacies or grocery stores without a prescription. OTC medication overuse is most prevalent in adolescents and young adults. This overuse is common due to the relatively low cost, widespread availability, low perceived dangers, and internet culture associated with OTC medications. OTC medications may be combination formulations that contain multiple drugs. These combination formulations are often used with other substances, which complicates treatment for these types of overdoses. Furthermore, t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
