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David Vetter
David Phillip Vetter (September 21, 1971 – February 22, 1984) was an American boy with severe combined immunodeficiency (SCID), a hereditary disease that dramatically weakens the immune system. Individuals born with SCID are abnormally susceptible to infections, and exposure to typically innocuous pathogens can be fatal. Vetter was referred to as "David, the bubble boy" by the media, as a reference to the complex containment system used as part of the management of his SCID. Vetter's surname was not revealed to the general public until 10 years after his death in order to preserve his family's privacy. In his first years of life, he lived mostly at Texas Children's Hospital in Houston, Texas. As he grew older, he lived increasingly at home with his parents and older sister Katherine in Dobbin, Texas. He died in 1984 at the age of 12. Family and birth Vetter's parents were Carol Ann and David Joseph Vetter Jr. Their first son, David Joseph III, was also born with SCID an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Houston, Texas
Houston ( ) is the List of cities in Texas by population, most populous city in the U.S. state of Texas and in the Southern United States. Located in Southeast Texas near Galveston Bay and the Gulf of Mexico, it is the county seat, seat of Harris County, Texas, Harris County, as well as the principal city of the Greater Houston metropolitan area, the fifth-most populous metropolitan statistical area in the United States and the List of Texas metropolitan areas, second-most populous in Texas after Dallas–Fort Worth metroplex, Dallas–Fort Worth. With a population of 2,314,157 in 2023, Houston is the List of United States cities by population, fourth-most populous city in the United States after New York City, Los Angeles, and Chicago, and the List of North American cities by population, sixth-most populous city in North America. Houston is the southeast anchor of the greater megaregion known as the Texas Triangle. Comprising a land area of , Houston is the List of United S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Experience
''American Experience'' is a television program airing on the Public Broadcasting Service (PBS) in the United States. The program airs documentaries, many of which have won awards, about important or interesting events and people in American history. The series premiered on October 4, 1988, and was originally titled ''The American Experience.'' It was shortened to ''American Experience'' during a rebrand and image update. The show has had a presence on the internet since 1995, and more than 100 ''American Experience'' programs are accompanied by their own internet websites, which provide background information on the subjects covered as well as teachers' guides and educational companion materials. The show is produced primarily by WGBH-TV in Boston, Massachusetts, though occasionally in the early seasons it was co-produced by other PBS stations such as WNET (Channel 13) in New York City. Some programs considered part of the ''American Experience'' collection were produced prior ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Travolta
John Joseph Travolta (born February 18, 1954) is an American actor. He began acting in television before transitioning into a leading man in films. List of awards and nominations received by John Travolta, His accolades include a Primetime Emmy Award and three Golden Globe Awards, in addition to nominations for two Academy Awards, a British Academy Film Award, and three Screen Actors Guild Awards. Travolta came to prominence starring in the sitcom ''Welcome Back, Kotter'' (1975–1979), followed by a supporting performance in ''Carrie (1976 film), Carrie'' (1976) and then leading roles in ''Grease (film), Grease'' (1978), ''Urban Cowboy'' (1980), and ''Blow Out'' (1981). He earned nominations for the Academy Award for Best Actor for his roles in ''Saturday Night Fever'' (1977) and ''Pulp Fiction'' (1994). His other notable films include ''Get Shorty (film), Get Shorty'' (1995), ''Broken Arrow (1996 film), Broken Arrow'' (1996), ''Michael (1996 film), Michael'' (1996), ''Face/O ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TV Movie
A television film, alternatively known as a television movie, made-for-TV film/movie, telefilm, telemovie or TV film/movie, is a film with a running time similar to a feature film that is produced and originally distributed by or to a terrestrial or cable television network, in contrast to theatrical films made for initial showing in movie theaters, direct-to-video films made for initial release on home video formats, and films released on or produced for streaming platforms. In certain cases, such films may also be referred to and shown as a miniseries, which typically indicates a film that has been divided into multiple parts or a series that contains a predetermined, limited number of episodes. Origins and history Precursors of "television movies" include ''Talk Faster, Mister'', which aired on WABD (now WNYW) in New York City on December 18, 1944, and was produced by RKO Pictures, and the 1957 '' The Pied Piper of Hamelin'', based on the poem by Robert Browning, and s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Boy In The Plastic Bubble
''The Boy in the Plastic Bubble'' is a 1976 American made for television drama film inspired by the lives of David Vetter and Ted DeVita, who lacked effective immune systems. It stars John Travolta, Glynnis O'Connor, Diana Hyland, Robert Reed, Ralph Bellamy and P.J. Soles. It was written by Douglas Day Stewart, produced by Aaron Spelling and Leonard Goldberg (who, at the time, produced ''Starsky and Hutch'' and ''Charlie's Angels''), and directed by Randal Kleiser, who would work with Travolta again in the 1978 hit musical film adaptation of '' Grease'' shortly after. The original music score was composed by Mark Snow. The theme song "What Would They Say" was written and sung by Paul Williams. William Howard Taft High School was used for filming. The TV movie first aired November 12, 1976 on ABC. In the United Kingdom, the TV movie was released on PAL DVD by Prism Leisure in 2001 before it finally made its terrestrial television debut on Channel 5 in 2006. Plot Jo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Woodlands, Texas
The Woodlands is a Special district (United States), special-purpose district and census-designated place (CDP) in the U.S. state of Texas in the Greater Houston, Houston–The Woodlands–Sugar Land metropolitan statistical area. The Woodlands is primarily located in Montgomery County, Texas, Montgomery County, with portions extending into Harris County, Texas, Harris County. The Woodlands is governed by The Woodlands Township, an organization that provides municipal services and is administered by an elected board of directors. As of the 2020 U.S. Census, the township had a population of 114,436 people. In 2021, The Howard Hughes Corporation estimated the population of The Woodlands was 119,000. History Early history The area that is now The Woodlands was used by the Akokisa and Bidai peoples, who relied on the fresh water of Spring Creek (Harris County, Texas), Spring Creek. In 1984, construction in the Indian Springs neighborhood near the creek discovered Bidai artifacts. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Conroe ISD
Conroe Independent School District (CISD) is a school district in Montgomery County, Texas. The current superintendent has been Dr. Curtis Null since June 2018. As of April 2024, Conroe ISD was the 9th largest school district in Texas and 60th largest in the United States. The district's headquarters are located in the Deane L. Sadler Administration/Technology Center in Conroe. The CISD area, which covers , is part of the Lone Star College System (formerly the North Harris Montgomery Community College District). For the 2018–2019 school year, the district received a score of 89 out of 100 from the Texas Education Agency. History The first school within Conroe ISD's current boundaries was built in 1886 and called, "Conroe Mill School." The building had one room and was open for five months each year. A Black school, school for African American students was started soon after inside a Baptist church. The school district was created on July 12, 1892 by order of the Commissio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New York Times
''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of the longest-running newspapers in the United States, the ''Times'' serves as one of the country's Newspaper of record, newspapers of record. , ''The New York Times'' had 9.13 million total and 8.83 million online subscribers, both by significant margins the List of newspapers in the United States, highest numbers for any newspaper in the United States; the total also included 296,330 print subscribers, making the ''Times'' the second-largest newspaper by print circulation in the United States, following ''The Wall Street Journal'', also based in New York City. ''The New York Times'' is published by the New York Times Company; since 1896, the company has been chaired by the Ochs-Sulzberger family, whose current chairman and the paper's publ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epstein–Barr Virus
The Epstein–Barr virus (EBV), also known as human herpesvirus 4 (HHV-4), is one of the nine known Herpesviridae#Human herpesvirus types, human herpesvirus types in the Herpesviridae, herpes family, and is one of the most common viruses in humans. EBV is a DNA virus#Double-stranded DNA viruses, double-stranded DNA virus. EBV is the first identified oncogenic virus, a virus that can cause cancer. EBV establishes permanent infection in human B cells. It uncommonly causes infectious mononucleosis and is also tightly linked to many Malignancy, malignant diseases (cancers and autoimmune diseases). Various vaccine formulations have been tested in animals and humans; however, none of them were able to prevent EBV infection, thus, no vaccine has been approved to date. Infectious mononucleosis ("mono" or "glandular fever"), is characterized by extreme fatigue, fever, sore throat, and swollen lymph nodes. EBV is also associated with various non-malignant, premalignant, and malignant E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virus Latency
Virus latency (or viral latency) is the ability of a pathogenic virus to lie dormant ( latent) within a cell, denoted as the lysogenic part of the viral life cycle. A latent viral infection is a type of persistent viral infection which is distinguished from a chronic viral infection. Latency is the phase in certain viruses' life cycles in which, after initial infection, proliferation of virus particles ceases. However, the viral genome is not eradicated. The virus can reactivate and begin producing large amounts of viral progeny (the lytic part of the viral life cycle) without the host becoming reinfected by new outside virus, and stays within the host indefinitely. Virus latency is not to be confused with clinical latency during the incubation period when a virus is ''not'' dormant. Mechanisms Episomal latency Episomal latency refers to the use of genetic episomes during latency. In this latency type, viral genes are stabilized, floating in the cytoplasm or nucl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bone Marrow
Bone marrow is a semi-solid biological tissue, tissue found within the Spongy bone, spongy (also known as cancellous) portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). It is composed of Blood cell, hematopoietic cells, marrow adipose tissue, and supportive stromal cells. In adult humans, bone marrow is primarily located in the Rib cage, ribs, vertebrae, sternum, and Pelvis, bones of the pelvis. Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a person weighing 73 kg (161 lbs) will have around 3.7 kg (8 lbs) of bone marrow. Human marrow produces approximately 500 billion blood cells per day, which join the Circulatory system, systemic circulation via permeable vasculature sinusoids within the medullary cavity. All types of Hematopoietic cell, hematopoietic cells, including both Myeloid tissue, myeloid and Lymphocyte, lymphoid lineages, are create ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Burkitt Lymphoma
Burkitt's lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center. It is named after Denis Parsons Burkitt, the Irish surgeon who first described the disease in 1958 while working in equatorial Africa. It is a highly aggressive form of cancer which often, but not always, manifests after a person develops acquired immunodeficiency from infection with Epstein–Barr virus, Epstein-Barr Virus or HIV, Human Immunodeficiency Virus (HIV). The overall cure rate for Burkitt's lymphoma in developed countries is about 90%. Burkitt's lymphoma is uncommon in adults, in whom it has a worse prognosis. Classification Burkitt lymphoma can be divided into three main clinical variants: the endemic, the Sporadic cancer, sporadic, and the immunodeficiency-associated variants. By morphology (biology), morphology (i.e., microscopic appearance), immunophenotype, and genetics, the variants of Burkitt lymphoma are alike. * The endemic variant (also called " ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
