|
David E. Green
David Ezra Green (August 5, 1910 – July 8, 1983) was an American biochemist who made significant contributions to the study of enzymes, particularly the electron transport chain and oxidative phosphorylation. Life and career Green was born in Brooklyn, New York, the son of Jennie (Marrow) and Hyman Levy Green, a garment manufacturer. His parents were Jewish immigrants from Russia and Germany. He was awarded a degree in biology from New York University. He then moved to England and worked for eight years at the University of Cambridge under the supervision of Malcolm Dixon, on redox reactions in biological systems. He received his PhD under Dixon in 1934 with a thesis entitled ''The Application of Oxidation-Reduction Potentials to Biological Systems.'' At the outbreak of the Second World War, Green moved back to America and established himself in a laboratory at Columbia University. Here he studied the metabolism of amino acids and the citric acid cycle. In 1948, Green moved to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brooklyn
Brooklyn is a Boroughs of New York City, borough of New York City located at the westernmost end of Long Island in the New York (state), State of New York. Formerly an independent city, the borough is coextensive with Kings County, one of twelve original counties established under English rule in 1683 in what was then the Province of New York. As of the 2020 United States census, the population stood at 2,736,074, making it the most populous of the five boroughs of New York City, and the most populous Administrative divisions of New York (state)#County, county in the state.Table 2: Population, Land Area, and Population Density by County, New York State - 2020 New York State Department of Health. Accessed January 2, 2024. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electron Transport Chain
An electron transport chain (ETC) is a series of protein complexes and other molecules which transfer electrons from electron donors to electron acceptors via redox reactions (both reduction and oxidation occurring simultaneously) and couples this electron transfer with the transfer of protons (H+ ions) across a membrane. Many of the enzymes in the electron transport chain are embedded within the membrane. The flow of electrons through the electron transport chain is an exergonic process. The energy from the redox reactions creates an electrochemical proton gradient that drives the synthesis of adenosine triphosphate (ATP). In aerobic respiration, the flow of electrons terminates with molecular oxygen as the final electron acceptor. In anaerobic respiration, other electron acceptors are used, such as sulfate. In an electron transport chain, the redox reactions are driven by the difference in the Gibbs free energy of reactants and products. The free energy released when ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American People Of Russian-Jewish Descent
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label that was previously known as Def American * American University, in Washington, D.C. Sports teams S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1983 Deaths
1983 saw both the official beginning of the Internet and the first mobile cellular telephone call. Events January * January 1 – The migration of the ARPANET to Internet protocol suite, TCP/IP is officially completed (this is considered to be the beginning of the true Internet). * January 6 – Pope John Paul II appoints a bishop over the Czechoslovak exile community, which the ''Rudé právo'' newspaper calls a "provocation." This begins a year-long disagreement between the Czechoslovak Socialist Republic and the Vatican City, Vatican, leading to the eventual restoration of diplomatic relations between the two states. * January 14 – The head of Bangladesh's military dictatorship, Hussain Muhammad Ershad, announces his intentions to "turn Bangladesh into an Islamic state." * January 18 – United States Secretary of the Interior, U.S. Secretary of the Interior James G. Watt makes controversial remarks blaming poor living conditions on Indian reservation, Native American re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1910 Births
Events January * January 6 – Abé language, Abé people in the French West Africa colony of Côte d'Ivoire rise against the colonial administration; the rebellion is brutally suppressed by the military. * January 8 – By the Treaty of Punakha, the Himalayan kingdom of Bhutan becomes a protectorate of the British Empire. * January 11 – Charcot Island is discovered by the Antarctic expedition led by French explorer Jean-Baptiste Charcot on the ship ''Pourquoi-Pas (1908), Pourquoi Pas?'' Charcot returns from his expedition on February 11. * January 12 – Great January Comet of 1910 first observed (perihelion: January 17). * January 15 – Amidst the constitutional crisis caused by the House of Lords rejecting the People's Budget the January 1910 United Kingdom general election is held resulting in a hung parliament with neither Liberals nor Conservatives gaining a majority. * January 21 – 1910 Great Flood of Paris, The Great Flood of Paris begins when the Seine over ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beta Oxidation
In biochemistry and metabolism, beta oxidation (also β-oxidation) is the catabolic process by which fatty acid molecules are broken down in the cytosol in prokaryotes and in the mitochondria in eukaryotes to generate acetyl-CoA. Acetyl-CoA enters the citric acid cycle, generating NADH and FADH2, which are electron carriers used in the electron transport chain. It is named as such because the beta carbon of the fatty acid chain undergoes oxidation and is converted to a carbonyl group to start the cycle all over again. Beta-oxidation is primarily facilitated by the mitochondrial trifunctional protein, an enzyme complex associated with the inner mitochondrial membrane, although very long chain fatty acids are oxidized in peroxisomes. The overall reaction for one cycle of beta oxidation is: :C''n''-acyl-CoA + FAD + NAD''+'' + H''2''O + CoA → C''n''-2-acyl-CoA + FADH''2'' + NADH + H''+'' + acetyl-CoA Activation and membrane transport Free fatty acids cannot penetrate any bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Citric Acid Cycle
The citric acid cycle—also known as the Krebs cycle, Szent–Györgyi–Krebs cycle, or TCA cycle (tricarboxylic acid cycle)—is a series of chemical reaction, biochemical reactions that release the energy stored in nutrients through acetyl-CoA Redox, oxidation. The energy released is available in the form of Adenosine triphosphate, ATP. The Hans Krebs (biochemist), Krebs cycle is used by organisms that generate energy via Cellular respiration, respiration, either anaerobic respiration, anaerobically or aerobic respiration, aerobically (organisms that Fermentation, ferment use different pathways). In addition, the cycle provides precursor (chemistry), precursors of certain amino acids, as well as the reducing agent nicotinamide adenine dinucleotide, NADH, which are used in other reactions. Its central importance to many Metabolic pathway, biochemical pathways suggests that it was one of the earliest metabolism components. Even though it is branded as a "cycle", it is not necessa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amino Acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although over 500 amino acids exist in nature, by far the most important are the 22 α-amino acids incorporated into proteins. Only these 22 appear in the genetic code of life. Amino acids can be classified according to the locations of the core structural functional groups ( alpha- , beta- , gamma- amino acids, etc.); other categories relate to polarity, ionization, and side-chain group type ( aliphatic, acyclic, aromatic, polar, etc.). In the form of proteins, amino-acid '' residues'' form the second-largest component (water being the largest) of human muscles and other tissues. Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. It is thought that they played a key role in enabling life on Earth and its emergence. Amino acids are formally named by the IUPAC- IUBMB Joint Commi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Redox
Redox ( , , reduction–oxidation or oxidation–reduction) is a type of chemical reaction in which the oxidation states of the reactants change. Oxidation is the loss of electrons or an increase in the oxidation state, while reduction is the gain of electrons or a decrease in the oxidation state. The oxidation and reduction processes occur simultaneously in the chemical reaction. There are two classes of redox reactions: * Electron transfer, Electron-transfer – Only one (usually) electron flows from the atom, ion, or molecule being oxidized to the atom, ion, or molecule that is reduced. This type of redox reaction is often discussed in terms of redox couples and electrode potentials. * Atom transfer – An atom transfers from one Substrate (chemistry), substrate to another. For example, in the rusting of iron, the oxidation state of iron atoms increases as the iron converts to an oxide, and simultaneously, the oxidation state of oxygen decreases as it accepts electrons r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jewish
Jews (, , ), or the Jewish people, are an ethnoreligious group and nation, originating from the Israelites of History of ancient Israel and Judah, ancient Israel and Judah. They also traditionally adhere to Judaism. Jewish ethnicity, religion, and community are highly interrelated, as Judaism is their ethnic religion, though it is not practiced by all ethnic Jews. Despite this, religious Jews regard Gerim, converts to Judaism as members of the Jewish nation, pursuant to the Conversion to Judaism, long-standing conversion process. The Israelites emerged from the pre-existing Canaanite peoples to establish Kingdom of Israel (Samaria), Israel and Kingdom of Judah, Judah in the Southern Levant during the Iron Age.John Day (Old Testament scholar), John Day (2005), ''In Search of Pre-Exilic Israel'', Bloomsbury Publishing, pp. 47.5 [48] 'In this sense, the emergence of ancient Israel is viewed not as the cause of the demise of Canaanite culture but as its upshot'. Originally, J ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
