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David A. Karnofsky
David Aryah Karnofsky (March 28, 1914 – August 31, 1969) was an American clinical oncologist. In 1940, while he was a resident at the Colis P. Huntington Memorial Laboratory for Cancer Research of Harvard University, David A. Karnofsky began clinical research in cancer, and devoted himself to this area throughout his career. He was an internationally recognized specialist in cancer chemotherapy and affiliated with the Division of Experimental Chemotherapy, Sloan-Kettering Institute for Cancer Research. Education and training David graduated from Belmont High School (Los Angeles, California) (1930), UCLA 1934. He received his masters (A.M, 1936) in biology from Stanford University with a thesis entitled ''Some effects of thyroidectomy on the mammary glands and some other organs in the rat.'' He received his medical degree (Alpha Omega Alpha 1940), also from Stanford University. In the early years of his career at the Collis P. Huntington Memorial Laboratory at Harvard University ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karnofsky Score
In medicine (oncology and other fields), performance status is an attempt to quantify cancer patients' general well-being and activities of daily life. This measure is used to determine whether they can receive chemotherapy, whether dose adjustment is necessary, and as a measure for the required intensity of palliative care. It is also used in oncological randomized controlled trials as a measure of quality of life. Scoring systems There are various scoring systems. The most generally used are the Karnofsky score and the Zubrod score, the latter being used in publications by the WHO. For children, the Lansky score is used. Another common system is the Eastern Cooperative Oncology Group (ECOG) system. Parallel scoring systems include the ''Global Assessment of Functioning'' (GAF) score, which has been incorporated as the fifth ''axis'' of the ''Diagnostic and Statistical Manual'' (DSM) of psychiatry. Karnofsky scoring The Karnofsky Performance Score (KPS) ranking runs from 100 t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemotherapy
Chemotherapy (often abbreviated chemo, sometimes CTX and CTx) is the type of cancer treatment that uses one or more anti-cancer drugs (list of chemotherapeutic agents, chemotherapeutic agents or alkylating agents) in a standard chemotherapy regimen, regimen. Chemotherapy may be given with a cure, curative intent (which almost always involves combinations of drugs), or it may aim only to prolong life or to Palliative care, reduce symptoms (Palliative care, palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''oncology#Specialties, medical oncology''. The term ''chemotherapy'' now means the non-specific use of intracellular poisons to inhibit mitosis (cell division) or to induce DNA damage (naturally occurring), DNA damage (so that DNA repair can augment chemotherapy). This meaning excludes the more-selective agents that block extracellular signals (signal transduction) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford University School Of Medicine Alumni
Leland Stanford Junior University, commonly referred to as Stanford University, is a private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth governor of and then-incumbent United States senator representing California) and his wife, Jane, in memory of their only child, Leland Jr. The university admitted its first students in 1891, opening as a coeducational and non-denominational institution. It struggled financially after Leland died in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, university provost Frederick Terman inspired an entrepreneurial culture to build a self-sufficient local industry (later Silicon Valley). In 1951, Stanford Research Park was established in Palo Alto as the world's first university research park. By 2021, the university had 2,288 tenure-line faculty, senior fellows, center fellows, and medical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Oncologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label that was previously known as Def American * American University, in Washington, D.C. Sports teams ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1969 Deaths
1969 (Roman numerals, MCMLXIX) was a common year starting on Wednesday of the Gregorian calendar, the 1969th year of the Common Era (CE) and ''Anno Domini'' (AD) designations, the 969th year of the 2nd millennium, the 69th year of the 20th century, and the 10th and last year of the 1960s decade. Events January * January 4 – The Government of Spain hands over Ifni to Morocco. * January 5 – Ariana Afghan Airlines Flight 701 crashes into a house on its approach to London's Gatwick Airport, killing 50 of the 62 people on board and two of the home's occupants. * January 14 – USS Enterprise fire, An explosion aboard the aircraft carrier USS Enterprise (CVN-65), USS ''Enterprise'' near Hawaii kills 28 and injures 314. * January 16 – First successful docking of two crewed spacecraft in orbit and the first transfer of crew from one space vehicle to another (by a space walk) between Soviet craft Soyuz 5 and Soyuz 4. * January 18 – Failure of Soyuz 5's service module to separ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1914 Births
This year saw the beginning of what became known as the First World War, after Archduke Franz Ferdinand of Austria, heir to the Austrian throne was Assassination of Archduke Franz Ferdinand, assassinated by Serbian nationalist Gavrilo Princip. It also saw the first airline to provide scheduled regular commercial passenger services with heavier-than-air aircraft, with the St. Petersburg–Tampa Airboat Line. Events January * January 1 – The St. Petersburg–Tampa Airboat Line in the United States starts services between St. Petersburg, Florida, St. Petersburg and Tampa, Florida, becoming the first airline to provide scheduled regular commercial passenger services with heavier-than-air aircraft, with Tony Jannus (the first federally-licensed pilot) conveying passengers in a Benoist XIV flying boat. Abram C. Pheil, mayor of St. Petersburg, is the first airline passenger, and over 3,000 people witness the first departure. * January 11 **The Sakurajima volcano in Japan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Obituary
An obituary (wikt:obit#Etymology 2, obit for short) is an Article (publishing), article about a recently death, deceased person. Newspapers often publish obituaries as Article (publishing), news articles. Although obituaries tend to focus on positive aspects of the subject's life, this is not always the case. According to Nigel Farndale, the Obituaries Editor of ''The Times'', obituaries ought to be "balanced accounts" written in a "deadpan" style, and should not read like a hagiography. In local newspapers, an obituary may be published for any local resident upon death. A necrology is a register or list of records of the deaths of people related to a particular organization, group or field, which may only contain the sparsest details, or small obituaries. Historical necrologies can be important sources of information. Two types of paid advertisements are related to obituaries. One, known as a death notice, usually appears in the Births, Marriages and Deaths (BMD) section of a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society Of Clinical Oncology
The American Society of Clinical Oncology (ASCO) is a professional organization representing physicians of all oncology sub-specialties who care for people with cancer. Founded in 1964 by Fred Ansfield, Harry Bisel, Herman Freckman, Arnoldus Goudsmit, Robert Talley, William Wilson, and Jane C. Wright, it has nearly 45,000 members worldwide. Physician education ASCO offers educational resources for cancer physicians and other health care professionals of clinical oncology. These include scientific meetings, educational conferences, professional workshops, and special symposia on issues of particular relevance and importance to oncologists and researchers. It also produced the patient information website, Cancer.Net. It publishes numerous journals, books, newsletters, and online and multimedia resources; it publishes the ''Journal of Clinical Oncology'' (JCO), the '' JCO Oncology Practice'' (JCO OP), and the ''JCO Global Oncology'' (JCO GO), '' JCO Clinical Cancer Informati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lung Cancer
Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor. Without treatment, tumors spread throughout the lung, damaging lung function. Eventually lung tumors metastasize, spreading to other parts of the body. Early lung cancer often has no symptoms and can only be detected by medical imaging. As the cancer progresses, most people experience nonspecific respiratory problems: coughing, shortness of breath, or chest pain. Other symptoms depend on the location and size of the tumor. Those suspected of having lung cancer typically undergo a series of imaging tests to determine the location and extent of any tumors. Definitive diagnosis of lung cancer requires a biopsy of the suspected tumor be examined by a patholo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Joseph H
Joseph is a common male name, derived from the Hebrew (). "Joseph" is used, along with "Josef (given name), Josef", mostly in English, French and partially German languages. This spelling is also found as a variant in the languages of the modern-day Nordic countries. In Portuguese language, Portuguese and Spanish language, Spanish, the name is "José". In Arabic, including in the Quran, the name is spelled , . In Kurdish language, Kurdish (''Kurdî''), the name is , Persian language, Persian, the name is , and in Turkish language, Turkish it is . In Pashto the name is spelled ''Esaf'' (ايسپ) and in Malayalam it is spelled ''Ousep'' (ഔസേപ്പ്). In Tamil language, Tamil, it is spelled as ''Yosepu'' (யோசேப்பு). The name has enjoyed significant popularity in its many forms in numerous countries, and ''Joseph'' was one of the two names, along with ''Robert'', to have remained in the top 10 boys' names list in the US from 1925 to 1972. It is especiall ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Corps
The Chemical Corps is the branch of the United States Army tasked with defending against and using chemical, biological, radiological, and nuclear ( CBRN) weapons. The Chemical Warfare Service was established on 28 June 1918, combining activities that until then had been dispersed among five separate agencies of the United States federal government. It was made a permanent branch of the Regular Army by the National Defense Act of 1920. In 1945, it was redesignated the Chemical Corps. History Origins Discussion of the topic dates back to the American Civil War. A letter to the War Department dated 5 April 1862 from New York City resident John Doughty proposed the use of chlorine shells to drive the Confederate Army from its positions. Doughty included a detailed drawing of the shell with his letter. It is unknown how the military reacted to Doughty's proposal but the letter was unnoticed in a pile of old official documents until modern times. Another American, Forrest Shephe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oncology
Oncology is a branch of medicine that deals with the study, treatment, diagnosis, and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's Etymology, etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is focused on the diagnosis of cancer in a person, therapy (e.g., surgery, chemotherapy, radiotherapy and other modalities), monitoring of patients after treatment, palliative care of people with advanced-stage cancers, Ethics, ethical questions surrounding cancer care, Screening (medicine), screening of patients, and the study of cancer treatments through clinical research. An oncologist typically focuses on a specialty area in cancer treatment, such as surgery, Radiation therapy, radiation, gynecology, gynecologic oncology, geriatrics, geriatric oncology, pediatrics, pediatric oncology, and various organ-specific disciplines (breast, brain, liver, among others). The exp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
