Darbinurad
Darbinurad is a investigational new drug that is being evaluated for the treatment of gout. It is a selective urate transporter 1 (URAT1) inhibitor that blocks the reabsorption of uric acid within the renal proximal tubule The proximal tubule is the segment of the nephron in kidneys which begins from the renal (tubular) pole of the Bowman's capsule to the beginning of loop of Henle. At this location, the glomerular parietal epithelial cells (PECs) lining bowman’s ..., thereby reducing serum uric acid concentrations. References Antigout agents Benzonitriles Carboxylic acids Cyclopropanes Disubstituted pyridines Thioethers {{musculoskeletal-drug-stub ...
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