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Daniel M. Davis
Daniel Michael Davis (born ) is Head of Life Sciences and Professor of Immunology at Imperial College London. Davis was previously Professor of Immunology at the University of Manchester. He is the author of ''Self Defence'', ''The Secret Body'', ''The Beautiful Cure'' and '' The Compatibility Gene''. His research, using microscopy to study immune cell biology has helped understand how immune cells interact with each other. He co-discovered the immunological synapse and membrane nanotubes. Education Davis has a doctorate in physics from Strathclyde University. Career He was professor of molecular immunology at Imperial College and director of research at the University of Manchester's collaborative centre for inflammation research. Davis is a recognised as an expert in the field by the Nature journal of immunology. Science communication Davis often speaks at science, literary and music festivals. He has written for the Times, Sunday Times, Observer, Guardian, New Scientist, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Imperial College London
Imperial College London, also known as Imperial, is a Public university, public research university in London, England. Its history began with Prince Albert of Saxe-Coburg and Gotha, Prince Albert, husband of Queen Victoria, who envisioned a Albertopolis, cultural district in South Kensington that included museums, colleges, and the Royal Albert Hall. In 1907, these colleges – the Royal College of Science, the Royal School of Mines, and the City and Guilds of London Institute – merged to form the Imperial College of Science and Technology. In 1988, Imperial merged with St Mary's Hospital, London, St Mary's Hospital Medical School and then with Charing Cross and Westminster Medical School to form the Imperial College School of Medicine. The Imperial Business School was established in 2003 and officially opened by Elizabeth II, Queen Elizabeth II. Formerly a constituent college of the University of London, Imperial became an independent university in 2007. Imperial is o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Manchester
The University of Manchester is a public university, public research university in Manchester, England. The main campus is south of Manchester city centre, Manchester City Centre on Wilmslow Road, Oxford Road. The University of Manchester is considered a red brick university, a product of the civic university movement of the late 19th century. The current University of Manchester was formed in 2004 following the merger of the University of Manchester Institute of Science and Technology (UMIST) and the Victoria University of Manchester. This followed a century of the two institutions working closely with one another. Additionally, the university owns and operates major cultural assets such as the Manchester Museum, The Whitworth art gallery, the John Rylands Library, the Tabley House, Tabley House Collection and the Jodrell Bank Observatory – a UNESCO World Heritage Site. The University of Manchester Institute of Science and Technology had its origins in the Manchester Mechan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Compatibility Gene
''The Compatibility Gene'' is a 2013 book about the discovery of the mechanism of compatibility in the human immune system by the English professor of immunology, Daniel M. Davis. It describes the history of immunology with the discovery of the principle of graft rejection by Peter Medawar in the 1950s, and the way the body distinguishes self from not-self via natural killer cells. The compatibility mechanism contributes also to the success of pregnancy by helping the placenta to form, and may play a role in mate selection. Context Author Daniel M. Davis has a doctorate in physics from Strathclyde University. He was professor of molecular immunology at Imperial College London and director of research at the University of Manchester's collaborative centre for inflammation research. Davis is a recognised as an expert in the field by the Nature journal of immunology. Davis is a recognised expert for his research in the immune synapse, membrane nanotubes, and natural killer cells. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunological Synapse
In immunology, an immunological synapse (or immune synapse) is the interface between an antigen-presenting cell or target cell and a lymphocyte such as a T cell, B cell, or natural killer cell. The interface was originally named after the neuronal synapse, with which it shares the main structural pattern. An immunological synapse consists of molecules involved in T cell activation, which compose typical patterns—activation clusters. Immunological synapses are the subject of much ongoing research. Structure and function The immune synapse is also known as the supramolecular activation cluster or SMAC. This structure is composed of concentric rings each containing segregated clusters of proteins—often referred to as the bull’s-eye model of the immunological synapse: * c-SMAC (central-SMAC) composed of the θ isoform of protein kinase C, CD2, CD4, CD8, CD28, Lck, and Fyn. * p-SMAC (peripheral-SMAC) within which the lymphocyte function-associated antigen-1 ( LFA-1) and the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Membrane Nanotubes
A tunneling nanotube (TNT) or membrane nanotube is a term that has been applied to cytoskeletal protrusions that extend from the plasma membrane which enable different animal cells to connect over long distances, sometimes over 100 μm between certain types of cells. Tunneling nanotubes that are less than 0.7 micrometers in diameter, have an actin structure and carry portions of plasma membrane between cells in both directions. Larger TNTs (>0.7 μm) contain an actin structure with microtubules and/or intermediate filaments, and can carry components such as vesicles and organelles between cells, including whole mitochondria. The diameter of TNTs ranges from 0.05 μm to 1.5 μm and they can reach lengths of several cell diameters. There have been two types of observed TNTs: open ended and closed ended. Open ended TNTs connect the cytoplasm of two cells. Closed ended TNTs do not have continuous cytoplasm as there is a gap junction cap that only allows small molecules and ions to fl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strathclyde University
The University of Strathclyde () is a public research university located in Glasgow, Scotland. Founded in 1796 as the Andersonian Institute, it is Glasgow's second-oldest university, having received its royal charter in 1964 as the first technological university in the United Kingdom. Taking its name from the historic Kingdom of Strathclyde, its combined enrollment of 25,000 undergraduate and graduate students ranks it Scotland's third-largest university, drawn with its staff from over 100 countries. The annual income of the institution for 2023–24 was £432.5 million of which £118.6 million was from research grants and contracts, with an expenditure of £278.1 million. History The university was founded in 1796 through the will of John Anderson, professor of Natural Philosophy at the University of Glasgow. He left the majority of his estate to create a second university in Glasgow which would focus on "Useful Learning" – specializing in practical su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Imperial College
Imperial College London, also known as Imperial, is a public research university in London, England. Its history began with Prince Albert, husband of Queen Victoria, who envisioned a cultural district in South Kensington that included museums, colleges, and the Royal Albert Hall. In 1907, these colleges – the Royal College of Science, the Royal School of Mines, and the City and Guilds of London Institute – merged to form the Imperial College of Science and Technology. In 1988, Imperial merged with St Mary's Hospital Medical School and then with Charing Cross and Westminster Medical School to form the Imperial College School of Medicine. The Imperial Business School was established in 2003 and officially opened by Queen Elizabeth II. Formerly a constituent college of the University of London, Imperial became an independent university in 2007. Imperial is organised into four faculties: Engineering, Medicine, Natural Sciences, and Business. The university fosters ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features Peer review, peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2022 ''Journal Citation Reports'' (with an ascribed impact factor of 50.5), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in the autumn of 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander MacMillan (publisher), Alexander MacMillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the j ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University
Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyman John Harvard (clergyman), John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of Colonial history of the United States, colonial-era Massachusetts Bay Colony. While never formally affiliated with any Religious denomination, denomination, Harvard trained Congregationalism in the United States, Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Natural Killer Cell
Natural killer cells, also known as NK cells, are a type of cytotoxic lymphocyte critical to the innate immune system. They are a kind of large granular lymphocytes (LGL), and belong to the rapidly expanding family of known innate lymphoid cells (ILC) and represent 5–20% of all circulating lymphocytes in humans. The role of NK cells is analogous to that of cytotoxic T cells in the vertebrate adaptive immune response. NK cells provide rapid responses to virus-infected cells, stressed cells, tumor cells, and other intracellular pathogens based on signals from several activating and inhibitory receptors. Most immune cells detect the antigen presented on MHC class I, major histocompatibility complex I (MHC-I) on infected cell surfaces, but NK cells can recognize and kill stressed cells in the absence of antibodies and MHC, allowing for a much faster immune reaction. They were named "natural killers" because of the notion that they do not require activation to kill cells that are m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academics Of The University Of Manchester , a person who is a researcher or has expertise in an academic discipline
{{Disambiguation ...
Academic means of or related to an academy, an institution learning. Academic or academics may also refer to: * Academic staff, or faculty, teachers or research staff * school of philosophers associated with the Platonic Academy in ancient Greece * The Academic, Irish indie rock band * "Academic", song by New Order from the 2015 album ''Music Complete'' Other uses *Academia (other) *Academy (other) *Faculty (other) *Scholar A scholar is a person who is a researcher or has expertise in an academic discipline. A scholar can also be an academic, who works as a professor, teacher, or researcher at a university. An academic usually holds an advanced degree or a termina ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
