Novichok Agents
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Novichok Agents
Novichok () is a family of nerve agents, some of which are binary chemical weapons. The agents were developed at the GosNIIOKhT state chemical research institute by the Soviet Union and Russia between 1971 and 1993. Some Novichok agents are solids at standard temperature and pressure, while others are liquids. Dispersal of solid form agents is thought possible if in ultrafine powder state. Russian scientists who developed the nerve agents claim they are the deadliest ever made, with some variants possibly five to eight times more potent than VX, and others up to ten times more potent than soman. Iran has also been associated with the production of such chemical agents. In the twenty-first century, Novichok agents came to public attention after they were used to poison opponents of the Russian government, including the Skripals and two others in Amesbury, UK (2018), as well as Alexei Navalny (2020), but Russian civil poisonings with this substance have been known since at ...
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Nerve Agents
Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of acetylcholine, a neurotransmitter. Nerve agents are irreversible acetylcholinesterase inhibitors used as poison. Poisoning by a nerve agent leads to constriction of pupils, profuse salivation, convulsions, and involuntary urination and defecation, with the first symptoms appearing in seconds after exposure. Death by asphyxiation or cardiac arrest may follow in minutes due to the loss of the body's control over respiratory and other muscles. Some nerve agents are readily vaporized or aerosolized, and the primary portal of entry into the body is the respiratory system. Nervous agents can also be absorbed through the skin, requiring that those likely to be subjected to such agents wear a full body suit in addition ...
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Poisoning Of Alexei Navalny
On 20 August 2020, Russian opposition leader and anti-corruption activist Alexei Navalny was poisoned with the Novichok agent, Novichok nerve agent and as a result, he was hospitalized in serious condition. During a flight from Tomsk to Moscow, he became ill and was taken to a hospital in Omsk after an emergency landing there, and then, he was Induced coma, put in a coma. He was evacuated to the Charité hospital in Berlin, Germany, two days later. The use of the nerve agent was confirmed by five Organisation for the Prohibition of Chemical Weapons (OPCW) certified laboratories. On 7 September, doctors announced that they had taken Navalny out of the induced coma and that his condition had improved. He was discharged from the hospital on 22 September 2020. The OPCW said that a cholinesterase inhibitor from the Novichok group was found in Navalny's blood, urine, skin samples and his water bottle. At the same time, the OPCW report clarified that Navalny was poisoned with a new type ...
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Lev Alexandrovich Fyodorov
Lev Alexandrovich Fyodorov (sometimes ''Fedorov''; Russian Лев Александрович Фёдоров; 10 June 1936, Moscow,- 12 August 2017) was a Russian chemist. He was employed at the V. I. Vernadskiy Institute of Geochemistry and Analytical Chemistry of the Russian Academy of Sciences, and became a member of the New York Academy of Sciences. Fyodorov was a chemical warfare officer. After studying chemistry at Lomonosov University, he received his doctorate in 1967 and his habilitation in 1983. After the end of the Soviet era, he published papers on chemical and biological weapons and chemical security. Together with Vil Mirzayanov, he is particularly noted for his part in the publication of details regarding the discovery of Novichok nerve agents, and the subsequent court case against Mirzayanov. Achievements In 1967 Fyodorov received his candidate degree in chemistry and he subsequently defended his doctorate thesis in 1983. He has authored several monographs and ar ...
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A-230
A-230 is an organophosphate nerve agent. It was developed in the Soviet Union under the FOLIANT program and is one of the group of compounds referred to as Novichok agents that were revealed by Vil Mirzayanov. A-230 is possibly the most potent nerve agent for which specific toxicity figures have been published, with a human lethal dose estimated to be less than 0.1 mg. However it was felt to be less suitable for weaponisation than other agents such as A-232 and A-234, due to issues with the liquid agent exhibiting low volatility and solidifying at low temperatures, as well as poor stability in the presence of water. Legal status A-230 has been added to Schedule 1 of the Annex on Chemicals of the Chemical Weapons Convention The Chemical Weapons Convention (CWC), officially the Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on their Destruction, is an arms control treaty administered by the Organisation for .. ...
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Mass Spectroscopy
Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a ''mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is used in many different fields and is applied to pure samples as well as complex mixtures. A mass spectrum is a type of plot of the ion signal as a function of the mass-to-charge ratio. These spectra are used to determine the elemental or isotopic signature of a sample, the masses of particles and of molecules, and to elucidate the chemical identity or structure of molecules and other chemical compounds. In a typical MS procedure, a sample, which may be solid, liquid, or gaseous, is ionized, for example by bombarding it with a beam of electrons. This may cause some of the sample's molecules to break up into positively charged fragments or simply become positively charged without fragmenting. These ions (fragments) are then separated accordin ...
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Berlin
Berlin ( ; ) is the Capital of Germany, capital and largest city of Germany, by both area and List of cities in Germany by population, population. With 3.7 million inhabitants, it has the List of cities in the European Union by population within city limits, highest population within its city limits of any city in the European Union. The city is also one of the states of Germany, being the List of German states by area, third smallest state in the country by area. Berlin is surrounded by the state of Brandenburg, and Brandenburg's capital Potsdam is nearby. The urban area of Berlin has a population of over 4.6 million and is therefore the most populous urban area in Germany. The Berlin/Brandenburg Metropolitan Region, Berlin-Brandenburg capital region has around 6.2 million inhabitants and is Germany's second-largest metropolitan region after the Rhine-Ruhr region, as well as the List of EU metropolitan areas by GDP, fifth-biggest metropolitan region by GDP in the European Union. ...
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Omsk
Omsk (; , ) is the administrative center and largest types of inhabited localities in Russia, city of Omsk Oblast, Russia. It is situated in southwestern Siberia and has a population of over one million. Omsk is the third List of cities and towns in Russia by population, largest city in Siberia after Novosibirsk and Krasnoyarsk, and the twelfth-largest city in Russia. It is an important transport node, serving as a train station for the Trans-Siberian Railway and as a staging post for the Irtysh, Irtysh River. During the Russian Empire, Imperial era, Omsk was the seat of the Governor General of Western Siberia and, later, of the Governor-Generalship of the Steppes, Governor General of the Steppes. For a brief period during the Russian Civil War in 1918–1920, it served as the capital of the anti-Bolshevik Russian State (1918–1920), Russian State and held the imperial gold reserves. Omsk serves as the episcopal see of the bishop of Omsk and Tara, Omsk Oblast, Tara, as well ...
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Alexei Navalny
Alexei Anatolyevich Navalny (, ; 4 June 197616 February 2024) was a Russian Opposition to Vladimir Putin in Russia, opposition leader, anti-corruption in Russia, corruption activist and political prisoner. He founded the Anti-Corruption Foundation (FBK) in 2011. He was List of Amnesty International-designated prisoners of conscience, recognised by Amnesty International as a prisoner of conscience and was awarded the Sakharov Prize for his work on human rights. Through his social media accounts, Navalny and his team published material about corruption in Russia, organised political demonstrations and promoted his campaigns. In a 2011 interview, he described Russia's ruling party—United Russia—as a "party of crooks and thieves", which became a popular byname. Navalny and the FBK have published investigations detailing alleged corruption by high-ranking Russian officials and their associates. Navalny twice received a suspended sentence for embezzlement, in 2013 and 2014. Bot ...
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Germany
Germany, officially the Federal Republic of Germany, is a country in Central Europe. It lies between the Baltic Sea and the North Sea to the north and the Alps to the south. Its sixteen States of Germany, constituent states have a total population of over 84 million in an area of , making it the most populous member state of the European Union. It borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The Capital of Germany, nation's capital and List of cities in Germany by population, most populous city is Berlin and its main financial centre is Frankfurt; the largest urban area is the Ruhr. Settlement in the territory of modern Germany began in the Lower Paleolithic, with various tribes inhabiting it from the Neolithic onward, chiefly the Celts. Various Germanic peoples, Germanic tribes have inhabited the northern parts of modern Germany since classical ...
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The Guardian
''The Guardian'' is a British daily newspaper. It was founded in Manchester in 1821 as ''The Manchester Guardian'' and changed its name in 1959, followed by a move to London. Along with its sister paper, ''The Guardian Weekly'', ''The Guardian'' is part of the Guardian Media Group, owned by the Scott Trust Limited. The trust was created in 1936 to "secure the financial and editorial independence of ''The Guardian'' in perpetuity and to safeguard the journalistic freedom and liberal values of ''The Guardian'' free from commercial or political interference". The trust was converted into a limited company in 2008, with a constitution written so as to maintain for ''The Guardian'' the same protections as were built into the structure of the Scott Trust by its creators. Profits are reinvested in its journalism rather than distributed to owners or shareholders. It is considered a newspaper of record in the UK. The editor-in-chief Katharine Viner succeeded Alan Rusbridger in 2015. S ...
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Poisoning Of Sergei And Yulia Skripal
The poisoning of Sergei and Yulia Skripal, also known as the Salisbury poisoning, was a botched assassination attempt to poison Sergei Skripal, a former Russian military officer and double agent for the British intelligence agencies in the city of Salisbury, England on 4 March 2018. Sergei and his daughter, Yulia Skripal, were poisoned by means of a Novichok nerve agent. Both spent several weeks in hospital in a critical condition, before being discharged. A police officer, Nick Bailey, was also taken into intensive care after attending the incident, and was later discharged. The British government accused Russia of attempted murder and announced a series of punitive measures against Russia, including the expulsion of diplomats. The UK's official assessment of the incident was supported by 28 other countries which responded similarly. Altogether, an unprecedented 153 Russian diplomats were expelled by the end of March 2018. Russia denied the accusations, expelled foreign diplo ...
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A-232
A-232 is an organophosphate nerve agent. It was developed in the Soviet Union under the FOLIANT program and is one of the group of compounds referred to as Novichok agents that were revealed by Vil Mirzayanov. A-232 is reportedly slightly less potent as a nerve agent compared to some of the other compounds in the series such as A-230 and A-234, having similar potency to the older nerve agent VR. However it proved to be the most versatile agent as it was chemically stable and remained a volatile liquid over a wide temperature range, making it able to be used in standard chemical munitions without requiring special delivery mechanisms to be developed. Legal status A-232 has been added to Schedule 1 of the Annex on Chemicals of the Chemical Weapons Convention The Chemical Weapons Convention (CWC), officially the Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on their Destruction, is an arms control treaty administered ...
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