A-230 is an

organophosphate In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure , a central phosphate molecule with alkyl or aromatic substituents. They can be considered ...

nerve agent Nerve agents, sometimes also called nerve gases, are a class of organic chemistry, organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (ACh ...

. It was developed in the

Soviet Union The Union of Soviet Socialist Republics. (USSR), commonly known as the Soviet Union, was a List of former transcontinental countries#Since 1700, transcontinental country that spanned much of Eurasia from 1922 until Dissolution of the Soviet ...

under the FOLIANT program and is one of the group of compounds referred to as Novichok agents that were revealed by

Vil Mirzayanov Vil Sultanovich Mirzayanov (, ; born 9 March 1935 in Starokangyshevo, Dyurtyulinsky District, Bashkortostan) is a Russian chemist of ethnic Tatar origin who now lives in the United States, best known for revealing secret chemical weapons experi ...

. A-230 is possibly the most potent nerve agent for which specific toxicity figures have been published, with a human lethal dose estimated to be less than 0.1 mg. However it was felt to be less suitable for weaponisation than other agents such as A-232 and A-234, due to issues with the liquid agent exhibiting low volatility and solidifying at low temperatures, as well as poor stability in the presence of water.

Legal status

A-230 has been added to Schedule 1 of the Annex on Chemicals of the

Chemical Weapons Convention The Chemical Weapons Convention (CWC), officially the Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on their Destruction, is an arms control treaty administered by the Organisation for ...

as of June 2020, and it has been explicitly named as an example compound for schedule 1.A.13. For chemicals listed in Schedule 1, the most stringent declaration and verification measures are in place combined with far-reaching limits and bans on production and use. It is notable to say that Annex 1 does not explicitly relate this structure to the name A-230, just add this particular structure to the prohibited compounds section.

References

{{Neurotoxins Acetylcholinesterase inhibitors Amidines Phosphonamidofluoridates Novichok agents

Legal status

See also

References