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Metascience
Metascience (also known as meta-research) is the use of scientific methodology to study science itself. Metascience seeks to increase the quality of scientific research while reducing inefficiency. It is also known as "research on research" and "the science of science", as it uses research methods to study how research is done and find where improvements can be made. Metascience concerns itself with all fields of research and has been described as "a bird's eye view of science". In the words of John Ioannidis, "Science is the best thing that has happened to human beings... but we can do it better." In 1966, an early meta-research paper examined the statistical methods of 295 papers published in ten high-profile medical journals. It found that "in almost 73% of the reports read... conclusions were drawn when the justification for these conclusions was invalid." Meta-research in the following decades found many methodological flaws, inefficiencies, and poor practices in research ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Ioannidis
John P. A. Ioannidis ( ; , ; born August 21, 1965) is a Greek-American physician-scientist, writer and Stanford University professor who has made contributions to evidence-based medicine, epidemiology, and clinical research. Ioannidis studies scientific research itself – in other words, meta-research – primarily in clinical medicine and the social sciences. He has served on the editorial board of over twenty scientific journals including ''Journal of the American Medical Association'' (''JAMA''), '' Journal of the National Cancer Institute'' (''JNCI'') and ''The Lancet''. Ioannidis's 2005 essay " Why Most Published Research Findings Are False" was the most-accessed article in the history of Public Library of Science (PLOS) as of 2020, with more than three million views. Ioannidis was a prominent opponent of lockdowns during the COVID-19 pandemic, and he has been accused of promoting conspiracy theories about COVID-19 policies and public health and safety measures. Ear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Replication Crisis
The replication crisis, also known as the reproducibility or replicability crisis, refers to the growing number of published scientific results that other researchers have been unable to reproduce or verify. Because the reproducibility of empirical results is an essential part of the scientific method, such failures undermine the credibility of theories that build on them and can call into question substantial parts of scientific knowledge. The replication crisis is frequently discussed in relation to psychology and medicine, wherein considerable efforts have been undertaken to reinvestigate the results of classic studies to determine whether they are reliable, and if they turn out not to be, the reasons for the failure. Data strongly indicate that other natural science, natural and social sciences are also affected. The phrase "replication crisis" was coined in the early 2010s as part of a growing awareness of the problem. Considerations of causes and remedies have given rise ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Why Most Published Research Findings Are False
] "Why Most Published Research Findings Are False" is a 2005 essay written by John Ioannidis, a professor at the Stanford School of Medicine, and published in '' PLOS Medicine''. It is considered foundational to the field of metascience. In the paper, Ioannidis argued that a large number, if not the majority, of published medical research papers contain results that cannot be replicated. In simple terms, the essay states that scientists use hypothesis testing to determine whether scientific discoveries are significant. Statistical significance is formalized in terms of probability, with its ''p-''value measure being reported in the scientific literature as a screening mechanism. Ioannidis posited assumptions about the way people perform and report these tests; then he constructed a statistical model which indicates that most published findings are likely false positive results. While the general arguments in the paper recommending reforms in scientific research methodology wer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research Methods
Research is creative and systematic work undertaken to increase the stock of knowledge. It involves the collection, organization, and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion of past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, economic, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research
Research is creative and systematic work undertaken to increase the stock of knowledge. It involves the collection, organization, and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion of past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, eco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychology
Psychology is the scientific study of mind and behavior. Its subject matter includes the behavior of humans and nonhumans, both consciousness, conscious and Unconscious mind, unconscious phenomena, and mental processes such as thoughts, feelings, and motivation, motives. Psychology is an academic discipline of immense scope, crossing the boundaries between the Natural science, natural and social sciences. Biological psychologists seek an understanding of the Emergence, emergent properties of brains, linking the discipline to neuroscience. As social scientists, psychologists aim to understand the behavior of individuals and groups.Hockenbury & Hockenbury. Psychology. Worth Publishers, 2010. A professional practitioner or researcher involved in the discipline is called a psychologist. Some psychologists can also be classified as Behavioural sciences, behavioral or Cognitive science, cognitive scientists. Some psychologists attempt to understand the role of mental functions in i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientific Methodology
Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which study the physical world, and the social sciences, which study individuals and societies. While referred to as the formal sciences, the study of logic, mathematics, and theoretical computer science are typically regarded as separate because they rely on deductive reasoning instead of the scientific method as their main methodology. Meanwhile, applied sciences are disciplines that use scientific knowledge for practical purposes, such as engineering and medicine. The history of science spans the majority of the historical record, with the earliest identifiable predecessors to modern science dating to the Bronze Age in Ancient Egypt, Egypt and Mesopotamia (). Their contributions to mathematics, astronomy, and medicine entered and shaped the Gree ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academic Peer Review
Scholarly peer review or academic peer review (also known as refereeing) is the process of having a draft version of a researcher's methods and findings reviewed (usually anonymously) by experts (or "peers") in the same field. Peer review is widely used for helping the academic publisher (that is, the editor-in-chief, the editorial board or the program committee) decide whether the work should be accepted, considered acceptable with revisions, or rejected for official publication in an academic journal, a monograph or in the proceedings of an academic conference. If the identities of authors are not revealed to each other, the procedure is called dual-anonymous peer review. Academic peer review requires a community of experts in a given (and often narrowly defined) academic field, who are qualified and able to perform reasonably impartial review. Impartial review, especially of work in less narrowly defined or inter-disciplinary fields, may be difficult to accomplish, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Grading Of Recommendations Assessment, Development And Evaluation (GRADE) Approach
The GRADE approach (Grading of Recommendations Assessment, Development and Evaluation) is a method of assessing the certainty in evidence (also known as quality of evidence or confidence in effect estimates) and the strength of recommendations in health care. It provides a structured and transparent evaluation of the importance of outcomes of alternative management strategies, acknowledgment of patients and the public values and preferences, and comprehensive criteria for downgrading and upgrading certainty in evidence. It has important implications for those summarizing evidence for systematic reviews, health technology assessments, and clinical practice guidelines as well as other decision makers. Background and history The GRADE began in the year 2000 as a collaboration of methodologists, guideline developers, biostatisticians, clinicians, public health scientists and other interested members. GRADE developed and implemented a common, transparent and sensible approach to gradi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Despina Koletsi
Despina may refer to: People * Despina Achladiotou, the Lady of Ro (c1890–1982), Greek patriot * Despina Chatzivassiliou-Tsovilis (born 1967), Secretary General of the Parliamentary Assembly of the Council of Europe (PACE) * Despina Delios, American beauty pageant contestant * Despina Georgiadou (born 1991), Greek fencer * Mary Despina Lekas (1928–2023), American surgeon * Despina Louca, Cypriot-American physicist * Debbie Matenopolous, born Despina Matenopoulos (born 1974), American television host * Despina Montagas (born 1961), Greek wrestler * Despina Olympiou (born 1975), Greek-Cypriot singer * Despina Papadopoulou (born 1979), Greek footballer * Despina Papamichail (born 1993), Greek tennis player * Despina Stokou (born 1978), Greek artist based in Los Angeles * Despina Storch (1894 or 1895–1918), Greek woman suspected of spying for Germany in World War I * Despina Stratigakos (born 1963), Canadian-born architectural historian and academic * Despina Vandi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Perverse Incentives
The phrase "perverse incentive" is often used in economics to describe an incentive structure with undesirable results, particularly when those effects are unexpected and contrary to the intentions of its designers. The results of a perverse incentive scheme are also sometimes called cobra effects, where people are incentivized to make a problem worse. This name was coined by economist Horst Siebert based on an anecdote taken from the British Raj. The British government, concerned about the number of venomous cobras in Delhi, offered a bounty for every dead cobra. Initially, this was a successful strategy; large numbers of snakes were killed for the reward. Eventually, however, people began to breed cobras for the income. When the government became aware of this, the reward program was scrapped. The cobra breeders set their snakes free, leading to an overall increase in the wild cobra population. Cited in Brickman, p. 326. Perverse incentives arise in various fields such as e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
