Cyathidium
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Cyathidium
''Saussurea'' is a genus of about 300 species of flowering plants in the tribe Cardueae within the family Asteraceae, native to cool temperate and arctic regions of East Asia, Europe, and North America, with the highest diversity in alpine habitats in the Himalayas and East Asia. Common names include saw-wort and snow lotus, the latter used for a number of high altitude species in East Asia. They are perennial herbaceous plants, ranging in height from dwarf alpine species 5–10 cm tall, to tall thistle-like plants up to 3 m tall. The leaves are produced in a dense basal rosette, and then spirally up the flowering stem. The flowers form in a dense head of small capitula, often surrounded by dense white to purple woolly hairs; the individual florets are also white to purple. The wool is densest in the high altitude species, and aids in the thermoregulation of the flowers, minimising frost damage at night and also preventing ultraviolet light damage from the intense high-altit ...
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Macrophages
Macrophages (; abbreviated MPhi, φ, MΦ or MP) are a type of white blood cell of the innate immune system that engulf and digest pathogens, such as cancer cells, microbes, cellular debris and foreign substances, which do not have proteins that are specific to healthy body cells on their surface. This self-protection method can be contrasted with that employed by Natural killer cell, Natural Killer cells. This process of engulfment and digestion is called phagocytosis; it acts to defend the host against infection and injury. Macrophages are found in essentially all tissues, where they patrol for potential pathogens by amoeboid movement. They take various forms (with various names) throughout the body (e.g., histiocytes, Kupffer cells, alveolar macrophages, microglia, and others), but all are part of the mononuclear phagocyte system. Besides phagocytosis, they play a critical role in nonspecific defense (innate immunity) and also help initiate specific defense mechanisms (adapti ...
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Lipopolysaccharide
Lipopolysaccharide (LPS), now more commonly known as endotoxin, is a collective term for components of the outermost membrane of the cell envelope of gram-negative bacteria, such as '' E. coli'' and ''Salmonella'' with a common structural architecture. Lipopolysaccharides are large molecules consisting of three parts: an outer core polysaccharide termed the O-antigen, an inner core oligosaccharide and Lipid A (from which toxicity is largely derived), all covalently linked. In current terminology, the term endotoxin is often used synonymously with LPS, although there are a few endotoxins (in the original sense of toxins that are inside the bacterial cell that are released when the cell disintegrates) that are not related to LPS, such as the so-called delta endotoxin proteins produced by '' Bacillus thuringiensis''. Lipopolysaccharides can have substantial impacts on human health, primarily through interactions with the immune system. LPS is a potent activator of the immune syst ...
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INOS
Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development. It may function as a retrograde neurotransmitter. Nitric oxide is mediated in mammals by the calcium-calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS). The inducible isoform, iNOS, involved in immune response, binds calmodulin at physiologically relevant concentrations, and produces NO as an immune defense mechanism, as NO is a free radical with an unpaired electron. It is the proximate cause of septic shock and may function in autoimmune disease. In the context of eukaryote biology, ''nitric oxide synthase'' refers to nitric-oxide synthase (NADPH) (), which catalyzes the reaction: * 2 L-arginine + 3 NADPH + 3 H+ + 4 O2 \rightleftharpoons 2 cit ...
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MRNA
In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of Protein biosynthesis, synthesizing a protein. mRNA is created during the process of Transcription (biology), transcription, where an enzyme (RNA polymerase) converts the gene into primary transcript mRNA (also known as pre-mRNA). This pre-mRNA usually still contains introns, regions that will not go on to code for the final amino acid sequence. These are removed in the process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read by the ribosome, and the ribosome creates the protein utilizing amino acids carried by transfer RNA (tRNA). This process is known as Translation (biology), translation. All of these processes form part of the central dogma of molecular biology, which describes the flow of geneti ...
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Dysmenorrhea
Dysmenorrhea, also known as period pain, painful periods or menstrual cramps, is pain during menstruation. Its usual onset occurs around the time that menstruation begins. Symptoms typically last less than three days. The pain is usually in the pelvis or lower abdomen. Other symptoms may include back pain, diarrhea or nausea. Dysmenorrhea can occur without an underlying problem. Underlying issues that can cause dysmenorrhea include uterine fibroids, adenomyosis, and most commonly, endometriosis. It is more common among those with heavy periods, irregular periods, those whose periods started before twelve years of age and those who have a low body weight. A pelvic exam and ultrasound in individuals who are sexually active may be useful for diagnosis. Conditions that should be ruled out include ectopic pregnancy, pelvic inflammatory disease, interstitial cystitis and chronic pelvic pain. Dysmenorrhea occurs less often in those who exercise regularly and those who ha ...
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Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects synovial joint, joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. The disease may also affect other parts of the body, including skin, eyes, lungs, heart, nerves, and blood. This may result in a anemia, low red blood cell count, pleurisy, inflammation around the lungs, and pericarditis, inflammation around the heart. Fever and low energy may also be present. Often, symptoms come on gradually over weeks to months. While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves the body's immune system attacking the joints. This results in inflammation and thickening of the synovium, joint capsule. It also affects the und ...
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Traditional Chinese Medicine
Traditional Chinese medicine (TCM) is an alternative medicine, alternative medical practice drawn from traditional medicine in China. A large share of its claims are pseudoscientific, with the majority of treatments having no robust evidence of effectiveness or logical mechanism of action. Some TCM ingredients Traditional Chinese medicine#Safety, are known to be toxic and cause disease, including cancer. Medicine in traditional China encompassed a range of sometimes competing health and healing practices, folk beliefs, Scholar-official, literati theory and Confucianism, Confucian philosophy, Chinese herbology, herbal remedies, Chinese food therapy, food, diet, exercise, medical specializations, and schools of thought. TCM as it exists today has been described as a largely 20th century invention. In the early twentieth century, Chinese cultural and political modernizers worked to eliminate traditional practices as backward and unscientific. Traditional practitioners then selec ...
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Saussurea Laniceps
''Saussurea laniceps'' (common name cotton-headed snow lotus, ) is a rare snow lotus found only in the Himalayas including Nepal southwest China (in Sikkim in India and in Sichuan, Tibet and Yunnan in China). It might also occur in northern Burma. It grows above about altitude on alpine scree slopes. It is reputed to have medicinal properties according to traditional Chinese medicine. Among the snow lotus, Saussurea laniceps is proven to be more effective for its anti-inflammatory and anti-nociceptive effects. Description and life cycle ''Saussurea laniceps'' is herbaceous plant that grows tall. It is perennial and monocarpic: individual plants grow slowly (for 7–10 years or more) and die after flowering. Reproductive plants produce a single enlarged inflorescence with 6–36 flower heads. Producing seed requires pollinators. ''Saussurea laniceps'' is pollinated by two generalist bumblebee species, '' Bombus rufofasticatus'' and '' Bombus festivus'', that appear to special ...
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Saussurea Lappa
''Dolomiaea costus'', formerly known as ''Saussurea costus'', commonly known as costus, Indian costus, kuth, or putchuk, is a species of thistle in the genus '' Dolomiaea'' native to South Asia and China. Rishi (Hindu) mystics of Kashmir especially ate this plant. Essential oils extracted from the root have been used in traditional medicine and in perfumes since ancient times. Costus is the root of this plant. The root of the plant is the key part used for medicinal or homeopathic purposes.Davidson, Tish. "Aucklandia." ''The Gale Encyclopedia of Alternative Medicine'', edited by Laurie J. Fundukian, 4th ed., vol. 1, Gale, 2014, pp. 197-198. ''Gale Virtual Reference Library'', Accessed 20 Nov. 2017. The root is also called by its Latin name ''radix aucklandiae'' (root of aucklandia). It has a large number of names in other languages, including ''kuṣṭha'' in Sanskrit; ''kust'' or ''qust'' in Arabic and Persian; ''kut'', ''kur'', and ''pachak'' in Hindi and Bengali, ''kostum'' ...
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