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Cryptosporidium Muris
''Cryptosporidium muris'' is a species of coccidium, first isolated from the gastric glands of the common mouse. ''Cryptosporidium'' does originate in common mice, specifically laboratory mice. However, it also has infected cows, dogs, cats, rats, rabbits, lambs, and humans and other primates. General characteristics ''Cryptosporidium muris'' infects dogs, rabbits, lambs, cats, humans, and non-human primates. This type of ''cryptosporidium'' infects people and animals by the oocyst acquired in water. If people or animals drink the water, then they could become infected and then complete the cycle by passing oocysts. People and animals can also become infected by being in water that has the oocysts present. The area where ''Cryptosporidium muris'' most commonly occurs is in Kenya, France, Thailand, and Indonesia. It also occurs in the western hemisphere but to a far lower amount. Diagnostics and prevention The current diagnostics for ''Cryptosporidium muris'' are Polymerase Ch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ernest Tyzzer
Ernest Edward Tyzzer (August 30, 1875 – January 23, 1965) was an American physician, pathologist and parasitologist. He was involved in cancer research but is particularly noted for his work in parasitology, describing numerous new species of avian parasites in a career spanning 40 years. Tyzzer attended Brown University from 1893–7, funding his studies on the proceeds of trapping animals such as fox and mink. Before attending medical school, he obtained master's degree on flounder (a type of flatfish), partly undertaken at Woods Hole Oceanographic Institution. He began at Harvard Medical School in 1898. In 1905, while an assistant in Pathology at Harvard, he studied the histology of the skin lesions in varicella, being the first to recognize inclusion bodies in varicella. In 1907, Tyzzer was a founder member of the American Association for Cancer Research, serving as its president from 1912–1913. In 1913, when he was an assistant professor and director of cancer resear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coccidium
Coccidia (Coccidiasina) are a subclass of microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida. As obligate intracellular parasites, they must live and reproduce within an animal cell. Coccidian parasites infect the intestinal tracts of animals, and are the largest group of apicomplexan protozoa. Infection with these parasites is known as coccidiosis. Coccidia can infect all mammals, some birds, some fish, some reptiles, and some amphibians. Most species of coccidia are species-specific in their host. An exception is ''Toxoplasma gondii'', which can infect all mammals, although it can only undergo sexual reproduction in cats. Depending on the species of coccidia, infection can cause fever, vomiting, diarrhea, muscle pain, and nervous system effects and changes to behavior, and may lead to death. Healthy adults may recover without medication—but those who are immunocompromised or young almost certainly requi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laboratory Mice
The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory animal sources for these mice are usually of the species ''Mus musculus''. They are the most commonly used mammalian research model and are used for research in genetics, physiology, psychology, medicine and other scientific disciplines. Mice belong to the Euarchontoglires clade, which includes humans. This close relationship, the associated high homology with humans, their ease of maintenance and handling, and their high reproduction rate, make mice particularly suitable models for human-oriented research. The laboratory mouse genome has been sequenced and many mouse genes have human homologues. Lab mice are sold at pet stores for snake food and can also be kept as pets. Other mouse species sometimes used in laboratory research include two American species, the white-footed mouse (''Peromyscus leucopus'') and the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polymerase Chain Reaction
The polymerase chain reaction (PCR) is a method widely used to make millions to billions of copies of a specific DNA sample rapidly, allowing scientists to amplify a very small sample of DNA (or a part of it) sufficiently to enable detailed study. PCR was invented in 1983 by American biochemist Kary Mullis at Cetus Corporation. Mullis and biochemist Michael Smith (chemist), Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of Ancient DNA, ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications including biomedical research and forensic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Restriction Fragment Length Polymorphism
In molecular biology, restriction fragment length polymorphism (RFLP) is a technique that exploits variations in homologous DNA sequences, known as polymorphisms, populations, or species or to pinpoint the locations of genes within a sequence. The term may refer to a polymorphism itself, as detected through the differing locations of restriction enzyme sites, or to a related laboratory technique by which such differences can be illustrated. In RFLP analysis, a DNA sample is digested into fragments by one or more restriction enzymes, and the resulting ''restriction fragments'' are then separated by gel electrophoresis according to their size. RFLP analysis is now largely obsolete due to the emergence of inexpensive DNA sequencing technologies, but it was the first DNA profiling technique inexpensive enough to see widespread application. RFLP analysis was an important early tool in genome mapping, localization of genes for genetic disorders, determination of risk for disease, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DNA Sequencing
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, thymine, cytosine, and guanine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has become indispensable for basic biological research, Genographic Project, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics. Comparing healthy and mutated DNA sequences can diagnose different diseases including various cancers, characterize antibody repertoire, and can be used to guide patient treatment. Having a quick way to sequence DNA allows for faster and more individualized medical care to be administered, and for more organisms to be identified and cataloged. The rapid advancements in DNA seque ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ultraviolet
Ultraviolet radiation, also known as simply UV, is electromagnetic radiation of wavelengths of 10–400 nanometers, shorter than that of visible light, but longer than X-rays. UV radiation is present in sunlight and constitutes about 10% of the total electromagnetic radiation output from the Sun. It is also produced by electric arcs, Cherenkov radiation, and specialized lights, such as mercury-vapor lamps, tanning lamps, and black lights. The photons of ultraviolet have greater energy than those of visible light, from about 3.1 to 12 electron volts, around the minimum energy required to ionize atoms. Although long-wavelength ultraviolet is not considered an ionizing radiation because its photons lack sufficient energy, it can induce chemical reactions and cause many substances to glow or fluoresce. Many practical applications, including chemical and biological effects, are derived from the way that UV radiation can interact with organic molecules. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Conoidasida
Conoidasida is a class of parasitic alveolates in the phylum Apicomplexa. The class was defined in 1988 by Levine and contains two subclasses – the coccidia and the gregarines. All members of this class have a complete, hollow, truncated conoid. Gregarines tend to parasitize invertebrates with the mature gamonts being extracellular; the coccidia mostly infect vertebrates and have intracellular gamonts. Description A conoid is found in most species and when present forms complete but truncated cone. Sexual and asexual reproduction are present in life cycle of all species. Each zygote normally forms an oocyst wall within which it undergoes meiosis. This is sometimes followed by mitosis. This process of sporogony produces mobile vermiform infectious sporozoites. Multiple mitotic divisions ( schizogony) also occur during merogony of the feeding stages (trophozoites) and during gametogony. Motility Microgametes of some species are flagellated. Locomotion of other gam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Waterborne Diseases
Waterborne diseases are conditions (meaning adverse effects on human health, such as death, disability, illness or disorders) caused by pathogenic micro-organisms that are transmitted by water. These diseases can be spread while bathing, washing, drinking water, or by eating food exposed to contaminated water. They are a pressing issue in rural areas amongst developing countries all over the world. While diarrhea and vomiting are the most commonly reported symptoms of waterborne illness, other symptoms can include skin, ear, respiratory, or eye problems. Lack of clean water supply, sanitation and hygiene (WASH) are major causes for the spread of waterborne diseases in a community. Therefore, reliable access to clean drinking water and sanitation is the main method to prevent waterborne diseases. Microorganisms causing diseases that characteristically are waterborne prominently include protozoa and bacteria, many of which are intestinal parasites, or invade the tissues or circul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
