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Conjuctiva
In the anatomy of the eye, the conjunctiva (: conjunctivae) is a thin mucous membrane that lines the inside of the eyelids and covers the sclera (the white of the eye). It is composed of non-keratinized, stratified squamous epithelium with goblet cells, stratified columnar epithelium and stratified cuboidal epithelium (depending on the zone). The conjunctiva is highly vascularised, with many microvessels easily accessible for imaging studies. Structure The conjunctiva is typically divided into three parts: Blood supply Blood to the bulbar conjunctiva is primarily derived from the ophthalmic artery. The blood supply to the palpebral conjunctiva (the eyelid) is derived from the external carotid artery. However, the circulations of the bulbar conjunctiva and palpebral conjunctiva are linked, so both bulbar conjunctival and palpebral conjunctival vessels are supplied by both the ophthalmic artery and the external carotid artery, to varying extents. Nerve supply Sensory innerva ...
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Lacrimal Artery
The lacrimal artery is an artery of the Orbit (anatomy), orbit. It is a branch of the ophthalmic artery. It accompanies the lacrimal nerve along the upper border of the lateral rectus muscle, travelling forward to reach the lacrimal gland. It supplies the lacrimal gland, as well as Extraocular muscles, two rectus muscles of the eye, the Eyelid, eyelids, and the conjunctiva. Structure Origin The lacrimal artery is normally a branch of the ophthalmic artery and represents one of its largest branches. Its origin occurs near the optic foramen, optic canal. It usually branches off the ophthalmic artery just after the ophthalmic artery's entry into the Orbit (anatomy), orbit. It can rarely arise before the ophthalmic artery enters the optic canal. Course and relations The lacrimal artery accompanies the lacrimal nerve along the upper border of the lateral rectus muscle. It travels anterior-ward to supply the lacrimal gland. Branches and distribution The lacrimal artery suppli ...
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Supraorbital Nerve
The supraorbital nerve is one of two terminal branches - the other being the supratrochlear nerve - of the frontal nerve (itself a branch of the ophthalmic nerve (CN V1)). It exits the orbit via the supraorbital foramen/notch before splitting into a medial branch and a lateral branch. It innervates the skin of the forehead, upper eyelid, and the root of the nose. Structure Origin The supraorbital nerve branches from the frontal nerve midway between the base and apex of the orbit. Course It travels anteriorly superior to the levator palpebrae superioris muscle. It exits the orbit through the supraorbital foramen/notch in the superior margin orbit, exiting it lateral to the supratrochlear nerve. It then ascends onto the forehead deep to the corrugator supercilii muscle and frontalis muscles. Fate It divides into a medial branch and lateral branch - usually after emerging from the orbit, but sometimes already within the orbit. Distribution The supraorbital nerv ...
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Immune System
The immune system is a network of biological systems that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to bacteria, as well as Tumor immunology, cancer cells, Parasitic worm, parasitic worms, and also objects such as wood splinters, distinguishing them from the organism's own healthy biological tissue, tissue. Many species have two major subsystems of the immune system. The innate immune system provides a preconfigured response to broad groups of situations and stimuli. The adaptive immune system provides a tailored response to each stimulus by learning to recognize molecules it has previously encountered. Both use humoral immunity, molecules and cell-mediated immunity, cells to perform their functions. Nearly all organisms have some kind of immune system. Bacteria have a rudimentary immune system in the form of enzymes that protect against bacteriophage, viral infections. Other basic immune mechanisms evolved in ancien ...
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Lacrimal Gland
The lacrimal glands are paired exocrine glands, one for each eye, found in most terrestrial vertebrates and some marine mammals, that secrete the aqueous layer of the tear film. In humans, they are situated in the upper lateral region of each orbit, in the lacrimal fossa of the orbit formed by the frontal bone. Inflammation of the lacrimal glands is called dacryoadenitis. The lacrimal gland produces tears which are secreted by the lacrimal ducts, and flow over the ocular surface, and then into canals that connect to the lacrimal sac. From that sac, the tears drain through the lacrimal duct into the nose. Anatomists divide the gland into two sections, a palpebral lobe, or portion, and an orbital lobe or portion. The smaller ''palpebral lobe'' lies close to the eye, along the inner surface of the eyelid; if the upper eyelid is everted, the palpebral portion can be seen. The orbital lobe of the gland, contains fine interlobular ducts that connect the orbital lobe and the palpe ...
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Mucus
Mucus (, ) is a slippery aqueous secretion produced by, and covering, mucous membranes. It is typically produced from cells found in mucous glands, although it may also originate from mixed glands, which contain both Serous fluid, serous and mucous cells. It is a viscous colloid containing inorganic ions, inorganic salts, antimicrobial enzymes (such as lysozymes), Antibody, immunoglobulins (especially Immunoglobulin A, IgA), and glycoproteins such as lactoferrin and mucins, which are produced by goblet cells in the mucous membranes and submucosal glands. Mucus covers the Epithelium, epithelial cells that interact with outside environment, serves to protect the linings of the respiratory system, respiratory, Digestion#Digestive system, digestive, and Genitourinary system, urogenital systems, and structures in the Visual system, visual and auditory systems from pathogenic Fungus, fungi, bacteria and viruses. Most of the mucus in the body is produced in the gastrointestinal tract. ...
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Lymphocyte
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an important subtype (which functions in cell-mediated, cytotoxic innate immunity). They are the main type of cell found in lymph, which prompted the name "lymphocyte" (with ''cyte'' meaning cell). Lymphocytes make up between 18% and 42% of circulating white blood cells. Types The three major types of lymphocyte are T cells, B cells and natural killer (NK) cells. They can also be classified as small lymphocytes and large lymphocytes based on their size and appearance. Lymphocytes can be identified by their large nucleus. T cells and B cells T cells (thymus cells) and B cells ( bone marrow- ...
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Melanocytes
Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart found in many mammals and birds. Melanin is a dark pigment primarily responsible for skin color. Once synthesized, melanin is contained in special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Thus darker skin tones have more melanosomes present than lighter skin tones. Functionally, melanin serves as protection against UV radiation. Melanocytes also have a role in the immune system. Function Through a process called melanogenesis, melanocytes produce melanin, which is a pigment found in the skin, eyes, hair, nasal cavity, and inner ear. This melanogenesis leads to a long-lasting pigmentation, which is in contrast to the pigmentation that originates from oxidation of al ...
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Tears
Tears are a clear liquid secreted by the lacrimal glands (tear gland) found in the eyes of all land mammals. Tears are made up of water, electrolytes, proteins, lipids, and mucins that form layers on the surface of eyes. The different types of tears—basal, reflex, and emotional—vary significantly in composition. The functions of tears include lubricating the eyes (basal tears), removing irritants (reflex tears), and also aiding the immune system. Tears also occur as a part of the body's natural pain response. Emotional secretion of tears may serve a biological function by excreting stress-inducing hormones built up through times of emotional distress. Tears have symbolic significance among humans. Physiology Chemical composition Tears are made up of three layers: lipid, aqueous, and mucous. Tears are composed of water, salts, antibodies, and lysozymes (antibacterial enzymes); though composition varies among different tear types. The composition of tears caused by an ...
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Accessory Lacrimal Glands
Krause's glands and Wolfring's glands (or Ciaccio's glands) are the accessory lacrimal glands of the lacrimal system of human eye. These glands are structurally and histologically similar to the Lacrimal gland, main lacrimal gland. Glands of Krause are located in the stroma of the conjunctival fornix, and the glands of Wolfring are located along the orbital border of the tarsal plate. These glands are oval and display numerous acini. The acini are surrounded, sometimes incompletely, by a row of myoepithelial cells. Animal studies suggest that the ducts of Wolfring glands have a tortuous course and open onto the palpebral conjunctiva. Like the main lacrimal gland, the accessory lacrimal glands are also densely innervated, but they lack parasympathetic innervation. These glands are exocrine glands, responsible for the basal (unstimulated) secretion of the middle aqueous layer of the Tears, tear film. 20 to 40 glands of Krause are found in the upper fornix, and 6-8 glands appear in t ...
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Goblet Cells
Goblet cells are simple columnar epithelial cells that secrete gel-forming mucins, like mucin 2 in the lower gastrointestinal tract, and mucin 5AC in the respiratory tract. The goblet cells mainly use the merocrine method of secretion, secreting vesicles into a duct, but may use apocrine methods, budding off their secretions, when under stress. The term ''goblet'' refers to the cell's goblet-like shape. The apical portion is shaped like a cup, as it is distended by abundant mucus laden granules; its basal portion lacks these granules and is shaped like a stem. The goblet cell is highly polarized with the nucleus and other organelles concentrated at the base of the cell and secretory granules containing mucin, at the apical surface. The apical plasma membrane projects short microvilli to give an increased surface area for secretion. Goblet cells are typically found in the respiratory, reproductive and lower gastrointestinal tract and are surrounded by other columnar cells. Bia ...
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Long Ciliary Nerves
The long ciliary nerves are 2-3 nerves that arise from the nasociliary nerve (itself a branch of the ophthalmic branch (CN V1) of the trigeminal nerve (CN V)). They enter the eyeball to provide sensory innervation to parts of the eye, and sympathetic visceral motor innervation to the dilator pupillae muscle. Anatomy Origin The long ciliary nerves branch from the nasociliary nerve as it crosses the optic nerve (CN II). Course Accompanied by the short ciliary nerves, the long ciliary nerves pierce and enter the posterior part of the sclera near where it is entered by the optic nerve, then run anterior-ward between the sclera and the choroid. Function The long ciliary nerves are distributed to the ciliary body, iris, and cornea. Sensory The long ciliary nerves provide sensory innervation to the eyeball, including the cornea. Sympathetic The long ciliary nerves contain post-ganglionic sympathetic fibers from the superior cervical ganglion for the dilator pupill ...
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Zygomaticofacial Nerve
The zygomaticofacial nerve (or zygomaticofacial branch of zygomatic nerve or malar branch of zygomatic nerve) is a cutaneous ( sensory) branch of the maxillary nerve (CN V2) that arises within the orbit. The zygomaticofacial nerve penetrates the inferolateral angle of the orbit, emerging into the face through the zygomaticofacial foramen, then penetrates the orbicularis oculi muscle to reach and innervate the skin of the prominence of the cheek. Anatomy Communications The zygomaticofacial nerve forms a nerve plexus A nerve plexus is a plexus (branching network) of intersecting nerves. A nerve plexus is composed of afferent and efferent fibers that arise from the merging of the anterior rami of spinal nerves and blood vessels. There are five spinal nerve ple ... with the zygomatic branches of facial nerve (CN VII), and the inferior palpebral branches of maxillary nerve (V2). Variation The nerve may sometimes be absent. References External links * * Maxill ...
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