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Color Health
Color Health, Inc. (founded as Color Genomics) is an American healthcare organization. History The company was co-founded in 2015 by Elad Gil, Nish Bhat, Taylor Sittler, and Othman Laraki, who is the CEO, in Burlingame, California. In November 2021, the company had a valuation of $4.6 billion and collected $100 million in a series E financing round. Expansion to population health Color provides technology, software, and clinical services for population health programs. Color has partnered with health systems including NorthShore University Health System, Ochsner Health System, and Jefferson Health. COVID-19 testing programs In early 2020, recognizing the growing threat that the COVID-19 pandemic presented, Color mobilized its existing software, logistics expertise and lab operations to focus on mass COVID-19 testing. Color operates a high-throughput CLIA-certified COVID-19 testing laboratory and processes thousands of samples a day. The integrated process includes sig ...
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Privately Held Company
A privately held company (or simply a private company) is a company whose Stock, shares and related rights or obligations are not offered for public subscription or publicly negotiated in their respective listed markets. Instead, the Private equity, company's stock is offered, owned, traded or exchanged privately, also known as "over-the-counter (finance), over-the-counter". Related terms are unlisted organisation, unquoted company and private equity. Private companies are often less well-known than their public company, publicly traded counterparts but still have major importance in the world's economy. For example, in 2008, the 441 list of largest private non-governmental companies by revenue, largest private companies in the United States accounted for $1.8 trillion in revenues and employed 6.2 million people, according to ''Forbes''. In general, all companies that are not owned by the government are classified as private enterprises. This definition encompasses both publ ...
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College Of American Pathologists
The College of American Pathologists (CAP) is a member-based physician organization founded in 1946, comprising approximately 18,000 board-certified pathologists. It serves patients, pathologists, and the public by fostering and advocating best practices in pathology and laboratory medicine. It is the world's largest association composed exclusively of pathologists certified by the American Board of Pathology, and is widely considered the leader in laboratory quality assurance. The CAP is an advocate for high-quality and cost-effective medical care. The CAP currently inspects and accredits medical laboratories under authority from the Centers for Medicare & Medicaid Services. Their standards have been called "the toughest and most exacting in the medical business." The CAP provides resources and guidance to laboratories seeking accreditation in programs for biorepositories, genomics, ISO 15189, and more. In November 2008, Piedmont Medical Laboratory of Winchester, Virginia ...
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All Of Us (initiative)
The All of Us Research Program (previously known as the Precision Medicine Initiative Cohort Program) is a precision medicine research program created in 2015 under the Obama Administration with $130 million in funding that aims to make advances in tailoring medical care to the individual's genetics. The mission of All of Us is to accelerate health and medical breakthroughs, enabling individualized prevention, treatment and care. The project aimed to collect genetic and health data from one million volunteers, and recruited around 297,549 participants. The project says its data is analyzed by 2,300 researchers. Program The initiative was announced during the 2015 State of the Union Address, and is run by the National Institutes of Health (NIH). The program is bilingual, with information and materials available in Spanish and English. Enrollment Eligible adults (18 and over) can enroll with the program. People who are not eligible are those in prison or people who cannot con ...
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National Institutes Of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Services (HHS). Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its scientific research through the NIH Intramural Research Program (IRP) and provides significant biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institution in the world, while, as of 2003, the extramural arm provided 28% of biomedical ...
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Partners HealthCare
Mass General Brigham (MGB) (formerly Partners HealthCare) is a not-for-profit, integrated health care system that engages in medical research, teaching, and patient care. It is the largest hospital-based research enterprise in the United States, with annual funding of more than $2 billion. The system's annual revenue was $20.6 billion in 2024. It is also an educational institution, founded by Brigham and Women's Hospital and Massachusetts General Hospital. The system provides clinical care through two academic hospitals, three specialty hospitals, seven community hospitals, home care services, a health insurance plan, and a robust network of specialty practices, urgent care facilities, and outpatient clinics/surgical centers. It is the largest private employer in Massachusetts. History Mass General Brigham was founded by the academic medical centers (AMCs) which give it its name: Massachusetts General Hospital (colloquially referred to as "Mass General") and Brigham and Women's ...
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Harvard University
Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyman John Harvard (clergyman), John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of Colonial history of the United States, colonial-era Massachusetts Bay Colony. While never formally affiliated with any Religious denomination, denomination, Harvard trained Congregationalism in the United States, Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston B ...
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Massachusetts Institute Of Technology
The Massachusetts Institute of Technology (MIT) is a Private university, private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of modern technology and science. In response to the increasing Technological and industrial history of the United States, industrialization of the United States, William Barton Rogers organized a school in Boston to create "useful knowledge." Initially funded by a land-grant universities, federal land grant, the institute adopted a Polytechnic, polytechnic model that stressed laboratory instruction in applied science and engineering. MIT moved from Boston to Cambridge in 1916 and grew rapidly through collaboration with private industry, military branches, and new federal basic research agencies, the formation of which was influenced by MIT faculty like Vannevar Bush. In the late twentieth century, MIT became a leading center for research in compu ...
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Broad Institute
The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: , pronunciation respelling: ), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States. The institute is independently governed and supported as a 501(c)(3) nonprofit research organization under the name Broad Institute Inc., and it partners with the Massachusetts Institute of Technology, Harvard University, and the five Harvard teaching hospitals. History The Broad Institute evolved from a decade of research collaborations among MIT and Harvard scientists. One cornerstone was the Center for Genome Research of Whitehead Institute at MIT. Founded in 1982, the Whitehead became a major center for genomics and the Human Genome Project. As early as 1995, scientists at the Whitehead started pilot projects in genomic medicine, forming an unofficial collaborative network among young scientists interested in genomic approaches to cancer and ...
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Loop-mediated Isothermal Amplification
Loop-mediated isothermal amplification (LAMP) is a single-tube technique for the amplification of DNA for diagnostic purposes and a low-cost alternative to detect certain diseases. LAMP is an isothermal nucleic acid amplification technique. In contrast to the polymerase chain reaction (PCR) technology, in which the reaction is carried out with a series of alternating temperature steps or cycles, isothermal amplification is carried out at a constant temperature, and does not require a thermal cycler. LAMP was invented in 1998 by Eiken Chemical Company in Tokyo.M. Soroka, B. Wasowicz, A. Rymaszewska: ''Loop-Mediated Isothermal Amplification (LAMP): The Better Sibling of PCR?'' In: ''Cells.'' Volume 10, issue 8, July 2021, p. , , PMID 34440699, . Reverse transcription loop-mediated isothermal amplification (RT-LAMP) combines LAMP with a reverse transcription step to allow the detection of RNA. __TOC__ Amplification In LAMP, the target sequence is amplified at a constant ...
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Nucleic Acid Amplification
The polymerase chain reaction (PCR) is a method widely used to make millions to billions of copies of a specific DNA sample rapidly, allowing scientists to amplify a very small sample of DNA (or a part of it) sufficiently to enable detailed study. PCR was invented in 1983 by American biochemist Kary Mullis at Cetus Corporation. Mullis and biochemist Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications including biomedical research and forensic science. The majority of PCR metho ...
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C). However, the agency also enforces other laws, notably Section 361 of the Public Health Service Act as well as associated regulations. Much of this regulatory-enforcement work is ...
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