|
Clyde E. Keeler
Clyde Edgar Keeler (April 11, 1900 – April 22, 1994) was a medical geneticist who is noted for his work on laboratory mice and the genetics of vision. His work was instrumental in the understanding of retinitis pigmentosa. He also seems to have published the first scientific paper on Intrinsically photosensitive retinal ganglion cells, non-rod non-cone visual sensation. Short biographies may be found at the web site of Georgia College, which keeps the Clyde E. Keeler collection, and at the Guggenheim Foundation, where he was List of Guggenheim Fellowships awarded in 1938, made a Fellow in 1938. His daughter, Irmgard Keeler Howard, wrote a three-page obituary for ''The Journal of Heredity'' and he self-published an autobiography, ''The Gene Hunter''. The manuscript is in the Keeler Collection. References 20th-century American zoologists American geneticists People from Marion, Ohio 1900 births 1994 deaths Harvard University alumni Scientists from Ohio Burials at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Phenotypic trait, Trait inheritance and Molecular genetics, molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the Cell (bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laboratory Mice
The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory animal sources for these mice are usually of the species ''Mus musculus''. They are the most commonly used mammalian research model and are used for research in genetics, physiology, psychology, medicine and other scientific disciplines. Mice belong to the Euarchontoglires clade, which includes humans. This close relationship, the associated high homology with humans, their ease of maintenance and handling, and their high reproduction rate, make mice particularly suitable models for human-oriented research. The laboratory mouse genome has been sequenced and many mouse genes have human homologues. Lab mice are sold at pet stores for snake food and can also be kept as pets. Other mouse species sometimes used in laboratory research include two American species, the white-footed mouse (''Peromyscus leucopus'') and the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University Alumni
The list of Harvard University alumni includes notable graduates, professors, and administrators affiliated with Harvard University. For a list of notable non-graduates of Harvard, see the list of Harvard University non-graduate alumni. For a list of Harvard's presidents, see President of Harvard University. Eight Presidents of the United States have graduated from Harvard University: John Adams, John Quincy Adams, Rutherford B. Hayes, John F. Kennedy, Franklin Delano Roosevelt, Theodore Roosevelt, George W. Bush, and Barack Obama. Bush graduated from Harvard Business School, Hayes and Obama from Harvard Law School, and the others from Harvard College. Over 150 Nobel Prize winners have been associated with the university as alumni, researchers or faculty. Nobel laureates Pulitzer Prize winners ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1994 Deaths
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked below. 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Earlier years ''Deaths in years earlier than this can usually be found in the main articles of the years.'' See also * Lists of deaths by day * Deaths by year (category) {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1900 Births
As of March 1 ( O.S. February 17), when the Julian calendar acknowledged a leap day and the Gregorian calendar did not, the Julian calendar fell one day further behind, bringing the difference to 13 days until February 28 ( O.S. February 15), 2100. Summary Political and military The year 1900 was the end of the 19th century and the beginning of the 20th century. Two days into the new year, the U.S. Secretary of State John Hay announced the Open Door Policy regarding China, advocating for equal access for all nations to the Chinese market. The Galveston hurricane would become the deadliest natural disaster in United States history, killing between 6,000 and 12,000 people, mostly in and near Galveston, Texas, as well as leaving 10,000 people homeless, destroying 7,000 buildings of all kinds in Galveston. As of 2025, it remains the fourth deadliest Atlantic hurricane on record. An ongoing Boxer Rebellion in China escalates with multiple attacks by the Boxers on Chines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Marion, Ohio
The term "the people" refers to the public or common mass of people of a polity. As such it is a concept of human rights law, international law as well as constitutional law, particularly used for claims of popular sovereignty. In contrast, a people is any plurality of persons considered as a whole. Used in politics and law, the term "a people" refers to the collective or community of an ethnic group or nation. Concepts Legal Chapter One, Article One of the Charter of the United Nations states that "peoples" have the right to self-determination. Though the mere status as peoples and the right to self-determination, as for example in the case of Indigenous peoples (''peoples'', as in all groups of indigenous people, not merely all indigenous persons as in ''indigenous people''), does not automatically provide for independent sovereignty and therefore secession. Indeed, judge Ivor Jennings identified the inherent problems in the right of "peoples" to self-determination, as i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Geneticists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label that was previously known as Def American * American University The American University (AU or A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Journal Of Heredity
The ''Journal of Heredity'' is a peer-reviewed scientific journal concerned with heredity in a biological sense, covering all aspects of genetics. It is published by Oxford University Press on behalf of the American Genetic Association. History The trends in topics that have been published in the journal reflect the history of the discipline of genetics.Crow, J F (2004). "Genetics: Alive and Well. The First Hundred Years as Viewed Through the Pages of the Journal of Heredity. WILHEMINE E. KEY 2003 INVITATIONAL LECTURE". J Hered (95(5):365–374. Early issues included many papers on eugenics, particularly under the editorial leadership of the journal's first two editors-in-chief, Paul Popenoe and R. C. Cook. Emphasis on eugenics in the journal declined throughout the 1940s and 1950s as support for the topic waned in the scientific community and the general public; when Cook's daughter, Barbara Kuhn, took over as editor in 1962 after her father's 40-year service, "...the subject ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Guggenheim Fellowships Awarded In 1938
Fifty-eight Guggenheim Fellowships were awarded in 1938. 1938 U.S. and Canadian Fellows 1938 Latin American and Caribbean Fellows See also * Guggenheim Fellowship * List of Guggenheim Fellowships awarded in 1937 * List of Guggenheim Fellowships awarded in 1939 References {{DEFAULTSORT:List Of Guggenheim Fellowships Awarded In 1938 1938 Events January * January 1 – state-owned enterprise, State-owned railway networks are created by merger, in France (SNCF) and the Netherlands (Nederlandse Spoorwegen – NS). * January 20 – King Farouk of Egypt marries Saf ... Guggenheim Guggenheim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intrinsically Photosensitive Retinal Ganglion Cells
Intrinsically photosensitive retinal ganglion cells (ipRGCs), also called photosensitive retinal ganglion cells (pRGC), or melanopsin-containing retinal ganglion cells (mRGCs), are a type of neuron in the retina of the mammalian eye. The presence of an additional photoreceptor was first suspected in 1927 when mice lacking rod and cone cells still responded to changing light levels through pupil constriction; this suggested that rods and cones are not the only light-sensitive tissue. However, it was unclear whether this light sensitivity arose from an additional retinal photoreceptor or elsewhere in the body. Recent research has shown that these retinal ganglion cells, unlike other retinal ganglion cells, are intrinsically photosensitive due to the presence of melanopsin, a light-sensitive protein. Therefore, they constitute a third class of photoreceptors, in addition to rod and cone cells. Overview Compared to the rods and cones, the ipRGCs respond more sluggishly and si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retinitis Pigmentosa
Retinitis pigmentosa (RP) is a member of a group of genetic disorders called inherited retinal dystrophy (IRD) that cause loss of vision. Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visual field). As peripheral vision worsens, people may experience " tunnel vision". Complete blindness is uncommon. Onset of symptoms is generally gradual and often begins in childhood. Retinitis pigmentosa is generally inherited from one or both parents. It is caused by genetic variants in nearly 100 genes. The underlying mechanism involves the progressive loss of rod photoreceptor cells that line the retina of the eyeball. The rod cells secrete a neuroprotective substance (rod-derived cone viability factor, RdCVF) that protects the cone cells from apoptosis. When these rod cells die, this substance is no longer provided. This is generally followed by the loss of cone photoreceptor cells. Diagnosis is through eye examination of the retina ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
