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Citrus Red 2
Citrus Red 2, Citrus Red No. 2, C.I. Solvent Red 80, or C.I. 12156 is an artificial dye. As a food dye, it has been permitted by the US Food and Drug Administration (FDA) since 1956 to color the skin of oranges. Citrus Red 2 is listed by the International Agency for Research on Cancer (IARC) as a group 2B carcinogen, a substance "possibly carcinogenic to humans". Properties Citrus Red 2 is an orange to yellow solid or a dark red powder with a melting point of 156 °C. It is not soluble in water, but is readily soluble in many organic solvents. Use In the United States, Citrus Red 2 has sometimes been used to color orange peels, subject to a limit of 2 milligrams per kilogram of oranges. It is permitted when the fruit is intended to be eaten, but not when the fruit is intended for processing; for example, to manufacture orange juice. On April 22, 2025, the FDA announced plans to phase out synthetic food dyes by the end of 2026. This decision, led by FDA Commissioner Martin M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food Dye
Food coloring, color additive or colorant is any dye, pigment, or substance that imparts color when it is added to food or beverages. Colorants can be supplied as liquids, powders, gels, or pastes. Food coloring is commonly used in commercial products and in domestic cooking. Food colorants are also used in various non-food applications, including cosmetics, pharmaceuticals, home craft projects, and medical devices. Some colorings may be natural, such as with carotenoids and anthocyanins extracted from plants or cochineal from insects, or may be synthesized, such as tartrazine yellow. In the manufacturing of foods, beverages and cosmetics, the safety of colorants is under constant scientific review and certification by national regulatory agencies, such as the European Food Safety Authority (EFSA) and US Food and Drug Administration (FDA), and by international reviewers, such as the Joint FAO/WHO Expert Committee on Food Additives. Purpose of food coloring People associate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C). However, the agency also enforces other laws, notably Section 361 of the Public Health Service Act as well as associated regulations. Much of this regulatory-enforcement work is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Agency For Research On Cancer
The International Agency for Research on Cancer (IARC; ) is an intergovernmental agency forming part of the World Health Organization of the United Nations. Its role is to conduct and coordinate research into the causes of cancer. It also cancer registry, collects and publishes disease surveillance, surveillance data regarding the occurrence of cancer worldwide. Its IARC monographs programme identifies carcinogenic hazards and evaluates environmental carcinogen, causes of cancer in humans. IARC has its own governing council, and in 1965 the first members were West Germany, France, Italy, the United Kingdom, and the United States of America. Today, IARC's membership has grown to 29 countries. History In late February 1963, after he experienced his spouse suffering and dying of cancer, journalist and Mouvement de la Paix, peace activist Yves Poggioli sent a letter to Emmanuel d'Astier de La Vigerie, Emmanuel d'Astier de la Vignerie relating his story, and urging support for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
IARC Group 2B Carcinogen
IARC group 2B substances, mixtures and exposure circumstances are those that have been classified as "possibly carcinogenic to humans" by the International Agency for Research on Cancer (IARC) as This category is used when there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals. It may also be used when there is insufficient evidence of carcinogenicity in humans but sufficient evidence in experimental animals. In some cases, an agent, mixture, or exposure circumstance with inadequate evidence of carcinogenicity in humans but limited evidence in experimental animals, combined with supporting evidence from other relevant data, may be included in this group. This list focuses on the hazard linked to the agents. This means that the carcinogenic agents are capable of causing cancer, but this does not take their risk into account, which is the probability of causing a cancer given the level of exposure to this ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Martin Makary
Martin Adel Makary () is a British-American surgeon, professor, author, and medical commentator who has served as the 27th Commissioner of Food and Drugs since 2025. He practices surgical oncology and gastrointestinal laparoscopic surgery at the Johns Hopkins Hospital, is Mark Ravitch Chair in Gastrointestinal Surgery at Johns Hopkins School of Medicine, and is the chief of Islet Transplant Surgery at Johns Hopkins. Makary is an advocate for disruptive innovation in medicine and physician-led initiatives, such as a surgical checklist that he developed at Johns Hopkins. In 2018, Makary was elected to the National Academy of Medicine. In November 2024, President-Elect Donald Trump announced Makary would be his nominee to head the Food and Drug Administration (FDA) as its commissioner. He was confirmed by the United States Senate in March 2025. While supporting universal masking early in the COVID-19 pandemic and vaccines for adults, he opposed broad vaccine mandates and cert ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Orange B
Orange B is a food dye from the azo dye group. It is approved by the Food and Drug Administration, United States Food and Drug Administration (FDA) for use only in hot dog and sausage casings or surfaces, up to 150 parts per million of the finished food weight. It is typically prepared as a disodium salt. Orange B was first approved by the FDA for use as a FD&C Act#Food coloring, certified food dye in 1966. However, in 1978, the FDA proposed removing it from the list of approved food additives due to concerns over potential carcinogenic contaminants, particularly the presence of 2-naphthylamine. Around the same time, its sole U.S. manufacturer, the William J. Stange Company, ceased production. Despite its non-use in food products since the late 20th century, the FDA did not formally revoke its approval. On April 22, 2025, the FDA announced plans to phase out synthetic food dyes by the end of 2026. This decision, led by FDA Commissioner Martin Makary, was driven by growing concern ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food Colorings
Food coloring, color additive or colorant is any dye, pigment, or substance that imparts color when it is added to food or beverages. Colorants can be supplied as liquids, powders, gels, or Paste (food), pastes. Food coloring is commonly used in commercial products and in domestic cooking. Food colorants are also used in various non-food applications, including cosmetics, pharmaceuticals, home craft projects, and medical devices. Some colorings may be natural, such as with carotenoids and anthocyanins extracted from plants or cochineal from insects, or may be synthesized, such as tartrazine yellow. In the manufacturing of foods, beverages and cosmetics, the food safety, safety of colorants is under constant scientific review and certification by national Regulatory agency, regulatory agencies, such as the European Food Safety Authority (EFSA) and US Food and Drug Administration (FDA), and by international reviewers, such as the Joint FAO/WHO Expert Committee on Food Additives. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Azo Dyes
Azo dyes are organic compounds bearing the functional group R−N=N−R′, in which R and R′ are usually aryl and substituted aryl groups. They are a commercially important family of azo compounds, i.e. compounds containing the C−N=N−C linkage. Azo dyes are synthetic dyes and do not occur naturally. Most azo dyes contain only one azo group but there are some that contain two or three azo groups, called "diazo dyes" and "triazo dyes" respectively. Azo dyes comprise 60–70% of all dyes used in food industry, food and textile industry, textile industries. Azo dyes are widely used to treat textile, textiles, leather, leather articles, and some foods. Chemically related derivatives of azo dyes include #Azo pigments, azo pigments, which are insoluble in water and other solvents. Classes Many kinds of azo dyes are known, and several classification systems exist. Some classes include disperse dyes, metal-complex dyes, reactive dyes, and substantive dyes. Also called direct d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Solvent Dyes
A solvent dye is a dye soluble in organic solvents. It is usually used as a solution in an organic solvent. Solvent dyes are used to color organic solvents, hydrocarbon fuels, waxes, lubricants, plastics, and other hydrocarbon-based nonpolar materials. Fuel dyes are one use of solvent dyes. Their molecules are typically nonpolar or little polar, and they do not undergo ionization. They are insoluble in water. They form a colloidal solution in solvents. They have poor (basic dyes) to good (metal complex based) light fastness. Solvent dyes are used for gold imitation (and other transparent metallic effects) of metallized polyester films. Also used in marking inks, inkjet inks, glass coloration, and so on. Names of solvent dyes are often generic, of the scheme "solvent <color> <number>", e.g. Solvent Red 24, Solvent Red 26, Solvent Red 164, Solvent Yellow 124, Solvent Blue 35, etc. Red and yellow solvent dyes are often azo dyes, green and blue ones tend to be anthra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
