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Christopher G. Tate
Christopher G. Tate FRS (born 5 May 1964) is an English membrane protein biochemist and molecular biologist who works at the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK. Tate is known for his contributions to the understanding of G protein-coupled receptors. Education Tate was awarded the degree of BSc (Hons) in biochemistry by the University of Bristol in 1985. He was then awarded a PhD in 1989 by the University of Bristol for his work on integral membrane proteins in the red blood cell, under the supervision of Michael J. A. Tanner. Career and research Tate worked as a postdoctoral researcher (1989–1992) at the Department of Biochemistry, Cambridge, on bacterial sugar transporters in the group of Peter J. F. Henderson. After obtaining a research fellowship at Girton College, Cambridge, he then moved in 1992 to the Medical Research Council Laboratory of Molecular Biology to work with Richard Henderson, initially on the serotonin transport ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laboratory Of Molecular Biology
The Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) is a research institute in Cambridge, England, involved in the revolution in molecular biology which occurred in the 1950–60s. Since then it has remained a major medical research laboratory at the forefront of scientific discovery, dedicated to improving the understanding of key biological processes at atomic, molecular and cellular levels using multidisciplinary methods, with a focus on using this knowledge to address key issues in human health. A new replacement building constructed close by to the original site on the Cambridge Biomedical Campus was opened by Queen Elizabeth II in May 2013. The road outside the new building is named Francis Crick Avenue after the 1962 joint Nobel Prize winner and LMB alumnus, who co-discovered the helical structure of DNA in 1953. History Origins: 1947-61 Max Perutz, following undergraduate training in organic chemistry, left Austria in 1936 and came to the University ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurotensin Receptor
Neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Two of the receptors encoded by the and genes contain seven transmembrane helices and are G protein coupled. Numerous crystal structures have been reported for the neurotensin receptor 1 (NTS1). The third receptor has a single transmembrane domain and is encoded by the gene. Ligands Agonists ;Peptide * Beta-lactotensin (NTS2) * JMV-449 * Neurotensin * Neuromedin N (NTS1 selective) * PD-149,163 (NTS1 selective, reduced amide bond 8-13 fragment of neurotensin) ;Non-peptide * NTS1 full agonist SRI-9829 * Partial agonists derived from SR-48692 Antagonists * Levocabastine Levocabastine (trade name Livostin or Livocab, depending on the region) is a selective second-generation H1 receptor antagonist which was discovered at Janssen Pharmaceutica in 1979. It is used for allergic conjunctivitis. As well as acting as ... (NTS2 selective, also H1 histamine antagonist) * SR- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century English Scientists
File:1st century collage.png, From top left, clockwise: Jesus is crucified by Roman authorities in Judaea (17th century painting). Four different men (Galba, Otho, Vitellius, and Vespasian) claim the title of Emperor within the span of a year; The Great Fire of Rome (18th-century painting) sees the destruction of two-thirds of the city, precipitating the empire's first persecution against Christians, who are blamed for the disaster; The Roman Colosseum is built and holds its inaugural games; Roman forces besiege Jerusalem during the First Jewish–Roman War (19th-century painting); The Trưng sisters lead a rebellion against the Chinese Han dynasty (anachronistic depiction); Boudica, queen of the British Iceni leads a rebellion against Rome (19th-century statue); Knife-shaped coin of the Xin dynasty., 335px rect 30 30 737 1077 Crucifixion of Jesus rect 767 30 1815 1077 Year of the Four Emperors rect 1846 30 3223 1077 Great Fire of Rome rect 30 1108 1106 2155 Boudican revolt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellows Of Girton College, Cambridge
{{disambiguation ...
Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places *Fellows, California, USA *Fellows, Wisconsin, ghost town, USA Other uses * Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton *Fellows (surname) *Mount Fellows, a mountain in Alaska See also *North Fellows Historic District, listed on the National Register of Historic Places in Wapello County, Iowa *Justice Fellows (other) Justice Fellows may refer to: * Grant Fellows (1865–1929), associate justice of the Michigan Supreme Court * Raymond Fellows (1885–1957), associate justice of the Maine Supreme Judicial Court {{disambiguation, tndis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alumni Of The University Of Bristol
This is a list of University of Bristol people, including a brief description of their notability. This list includes not just former students but persons who are or have been associated with the university, including former academics, Chancellors, and recipients of honorary degrees. Staff and academics Chancellors and Vice-Chancellors Alumni Government and politics United Kingdom International The Law *Alexander Cameron (barrister), Alexander Cameron, English Barrister *Eve Cornwell, YouTuber and former lawyer *Sir Richard Field (judge), Richard Field, English High Court judge (England and Wales), High Court Judge, Academic of University of British Columbia, University of Hong Kong, McGill University * Louisa Ghevaert, British family law lawyer *Brenda Hale, Baroness Hale of Richmond, English judge and first woman to be appointed as the President of the Supreme Court of the United Kingdom, Chancellor of university (2004–2016) * Sir Stephen Laws, British lawyer and civ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
English Biochemists
English usually refers to: * English language * English people English may also refer to: Culture, language and peoples * ''English'', an adjective for something of, from, or related to England * ''English'', an Amish term for non-Amish, regardless of ethnicity * English studies, the study of English language and literature Media * ''English'' (2013 film), a Malayalam-language film * ''English'' (novel), a Chinese book by Wang Gang ** ''English'' (2018 film), a Chinese adaptation * ''The English'' (TV series), a 2022 Western-genre miniseries * ''English'' (play), a 2022 play by Sanaz Toossi People and fictional characters * English (surname), a list of people and fictional characters * English Fisher (1928–2011), American boxing coach * English Gardner (born 1992), American track and field sprinter * English McConnell (1882–1928), Irish footballer * Aiden English, a ring name of Matthew Rehwoldt (born 1987), American former professional wrestler ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1964 Births
Events January * January 1 – The Federation of Rhodesia and Nyasaland is dissolved. * January 5 – In the first meeting between leaders of the Roman Catholic and Orthodox churches since the fifteenth century, Pope Paul VI and Patriarch Athenagoras I of Constantinople meet in Jerusalem. * January 6 – A British firm, the Leyland Motors, Leyland Motor Corp., announces the sale of 450 buses to the Cuban government, challenging the United States blockade of Cuba. * January 9 – ''Martyrs' Day (Panama), Martyrs' Day'': Armed clashes between United States troops and Panamanian civilians in the Panama Canal Zone precipitate a major international crisis, resulting in the deaths of 21 Panamanians and 4 U.S. soldiers. * January 11 – United States Surgeon General Luther Terry reports that smoking may be hazardous to one's health (the first such statement from the U.S. government). * January 22 – Kenneth Kaunda is inaugurated as the first Prime Minister of Northern Rhodesi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adenosine A2A Receptor
The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, and also denotes the human gene encoding it. Structure This protein is a member of the G protein-coupled receptor (GPCR) family which possess seven transmembrane alpha helices, as well as an extracellular N-terminus and an intracellular C-terminus. Furthermore, located in the intracellular side close to the membrane is a small alpha helix, often referred to as helix 8 (H8). The crystallographic structure of the adenosine A2A receptor reveals a ligand binding pocket distinct from that of other structurally determined GPCRs (i.e., the beta-2 adrenergic receptor and rhodopsin).; Below this primary ( orthosteric) binding pocket lies a secondary ( allosteric) binding pocket. The crystal-structure of A2A bound to the antagonist ZM241385 (PDB code: 4EIY) showed that a sodium-ion can be found in this location of the protein, thus giving it the name 'sodium-ion binding pocket'. Heteromers The actions of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Bristol
The University of Bristol is a public university, public research university in Bristol, England. It received its royal charter in 1909, although it can trace its roots to a Merchant Venturers' school founded in 1595 and University College, Bristol, which had been in existence since 1876. Bristol Medical School, founded in 1833, was merged with the University College in 1893, and later became the university's school of medicine. The university is organised into #Academic structure, six academic faculties composed of multiple schools and departments running over 200 undergraduate courses, largely in the Tyndalls Park area of the city. It had a total income of £1.06 billion in 2023–24, of which £294.1 million was from research grants and contracts, with an expenditure of £768.7 million. It is the largest independent employer in Bristol. Current academics include 23 fellows of the Academy of Medical Sciences, 13 fellows of the British Academy, 43 fellows of the Academy of Soc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
