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Chlorobenzoic Acid
Chlorobenzoic acid may refer to: * 2-Chlorobenzoic acid * 3-Chlorobenzoic acid * 4-Chlorobenzoic acid Chlorobenzene derivatives Benzoic acids {{Authority control ...
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2-Chlorobenzoic Acid
2-Chlorobenzoic acid is an organic compound with the formula ClC6H4CO2H. It is one of three isomeric chlorobenzoic acids, the one that is the strongest acid. This white solid is used as a precursor to a variety of drugs, food additives, and dyes.Takao Maki, Kazuo Takeda "Benzoic Acid and Derivatives" in Ullmann's Encyclopedia of Industrial Chemistry 2002, Wiley-VCH, Weinheim. . Synthesis and reactions It is prepared by the oxidation of 2- chlorotoluene. The laboratory scale reaction employs potassium permanganate. Alternatively it arises by the hydrolysis of α,α,α-trichloro-2-toluene. The chloride is readily replaced by ammonia to 2-aminobenzoic acid. Similarly, the chloride is displaced by diphenylphosphide, leading to 2-diphenylphosphinobenzoic acid 2-Diphenylphosphinobenzoic acid is an organophosphorus compound with the formula (C6H5)2PC6H4CO2H. It is a white solid that dissolves in polar organic solvents. The ligand is a component of catalysts used for the Shell ...
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3-Chlorobenzoic Acid
3-Chlorobenzoic acid is an organic compound with the molecular formula ClC6H4CO2H. It is a white solid that is soluble in some organic solvents and in aqueous base. Synthesis and occurrence 3-Chlorobenzoic acid is prepared by oxidation of 3-chlorotoluene. It is a metabolic byproduct of the drug bupropion Bupropion, sold under the brand names Wellbutrin and Zyban among others, is an atypical antidepressant primarily used to treat major depressive disorder and to support smoking cessation. It is also popular as an add-on medication in the case .... References {{DEFAULTSORT:Chlorobenzoic acid, 3- Benzoic acids Chlorobenzene derivatives Human drug metabolites ...
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Chlorobenzene Derivatives
Chlorobenzene is an aromatic organic compound with the chemical formula C6H5Cl. This colorless, flammable liquid is a common solvent and a widely used intermediate in the manufacture of other chemicals. Uses Historical The major use of chlorobenzene is as an intermediate in the production of herbicides, dyestuffs, and rubber. Chlorobenzene is also used as a high-boiling solvent in industrial applications as well as in the laboratory. Chlorobenzene is nitrated on a large scale to give a mixture of 2-nitrochlorobenzene and 4-nitrochlorobenzene, which are separated. These mononitrochlorobenzenes are converted to related 2-nitrophenol, 2-nitroanisole, bis(2-nitrophenyl)disulfide, and 2-nitroaniline by nucleophilic displacement of the chloride, with respectively sodium hydroxide, sodium methoxide, sodium disulfide, and ammonia. The conversions of the 4-nitro derivative are similar. Chlorobenzene once was used in the manufacture of pesticides, most notably DDT, by reaction with ch ...
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