Charles David Allis
Charles David Allis (March 22, 1951 – January 8, 2023) was an American molecular biologist, and the Joy and Jack Fishman Professor at the Rockefeller University. He was also the Head of the Laboratory of Chromatin Biology and Epigenetics, and a professor at the Tri-Institutional MD–PhD Program (the other two institutions being the Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine). Early life and education Allis was born and raised in Cincinnati, Ohio. His father was a city planner and his mother an elementary school teacher. He entered the University of Cincinnati in 1969, majoring in biology. He had his first experience of basic research in his senior (or fourth) year of Bachelor of Science. The experience attracted him to research, and he went to Indiana University Bloomington for graduate studies. He graduated with an MSc in 1975 and a PhD three years later, under the supervision of Anthony Mahowald. Career Allis undertook a postdoctoral fellowship i ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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The Cincinnati Enquirer
''The Cincinnati Enquirer'' is a morning daily newspaper published by Gannett in Cincinnati, Ohio, United States. First published in 1841, the ''Enquirer'' is the last remaining daily newspaper in Greater Cincinnati and Northern Kentucky, although the daily ''Journal-News'' competes with the ''Enquirer'' in the northern suburbs. The ''Enquirer'' has the highest circulation of any print publication in the Cincinnati metropolitan area. A daily local edition for Northern Kentucky is published as ''The Kentucky Enquirer''. In addition to the ''Cincinnati Enquirer'' and ''Kentucky Enquirer'', Gannett publishes a variety of print and electronic periodicals in the Cincinnati area, including 16 ''Community Press'' weekly newspapers, 10 ''Community Recorder'' weekly newspapers, and ''OurTown'' magazine. The ''Enquirer'' is available online at the ''Cincinnati.com'' website. The paper has won two Pulitzer Prizes, in 1991 and 2018. Content ''The Kentucky Enquirer'' consists of an additiona ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Anthony Mahowald
Anthony Mahowald (born November 24, 1932) is a molecular genetics and cellular biologist who served as the department chair of the molecular genetics and cellular biology department at the University of Chicago. His lab focused on the fruit fly ''Drosophila melanogaster'', specifically focusing on controlling the genetic aspects of major developmental events. His major research breakthroughs included the study of the stem cell niche, endocycles, and various types of actin. Personal life Anthony Mahowald is married and has three children. Educational career Anthony Mahowald was born in Albany, Minnesota, on November 24, 1932. Mahowald received a bachelor's degree from Spring Hill College in Mobile, Alabama. Following his undergraduate studies, Mahowald earned his Ph.D. from Johns Hopkins University in 1962. At Johns Hopkins, Mahowald studied the structure of pole cells and polar granules in Drosophila melanogaster. Both his undergraduate and doctoral degrees were in the field ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in Manhattan in New York City. MSKCC is one of 72 National Cancer Institute– designated Comprehensive Cancer Centers. Its main campus is located at 1275 York Avenue between 67th and 68th Streets in Manhattan. It was formed in 1980 from the merger of the ''Memorial Hospital for the Treatment of Cancer and Allied Diseases'', founded in 1884, and the adjacent ''Sloan-Kettering Institute for Cancer Research'', founded in 1945. The two medical entities had formally coordinated their operations since 1960. History Early history of Memorial Hospital (1884–1934) The hospital was founded in its original building on the Upper West Side of Manhattan in 1884 as ''New York Cancer Hospital'' by a group that included John Jacob Astor III and his wife Charlotte. The hospital appointed as an attending surgeon William B. Coley, who pioneered an early form of immunotherapy to erad ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tri-Institutional MD–PhD Program
The Tri-Institutional MD–PhD Program is a MD–PhD degree program based in Upper East Side, New York City. Introduced in 1991, the current program is operated by Weill Cornell Medicine, Rockefeller University, and Memorial Sloan Kettering Cancer Center's Sloan Kettering Institute. The program is currently directed by Katharine C. Hsu. Profile Students who complete the program are awarded an M.D. from Weill Cornell Medical College and a Ph.D. from either Weill Cornell Medicine Graduate School of Medical Sciences, Rockefeller University, or the Gerstner Sloan Kettering Graduate School of Biomedical Sciences. In 2019, the program processed over 500 applications for 18 spots. These positions are funded by the National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Hu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chromatin
Chromatin is a complex of DNA and protein found in eukaryote, eukaryotic cells. The primary function is to package long DNA molecules into more compact, denser structures. This prevents the strands from becoming tangled and also plays important roles in reinforcing the DNA during cell division, preventing DNA repair#DNA damage, DNA damage, and regulating gene expression and DNA replication. During mitosis and meiosis, chromatin facilitates proper segregation of the chromosomes in anaphase; the characteristic shapes of chromosomes visible during this stage are the result of DNA being coiled into highly condensed chromatin. The primary protein components of chromatin are histones. An octamer of two sets of four histone cores (Histone H2A, Histone H2B, Histone H3, and Histone H4) bind to DNA and function as "anchors" around which the strands are wound.Maeshima, K., Ide, S., & Babokhov, M. (2019). Dynamic chromatin organization without the 30 nm fiber. ''Current opinion in cell biolog ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Jack Fishman
Jack Fishman (September 30, 1930 – December 7, 2013), born Jacob Fiszman, was a Jewish-American pharmaceutical researcher from Kraków, Poland. In 1961, along with Mozes J. Lewenstein, he developed the medication naloxone, which can reverse an opioid overdose, and the Centers for Disease Control and Prevention has described as a "a life-saving medication that can reverse an overdose from opioids—including heroin, fentanyl, and prescription opioid medications." Personal life He fled the Nazi occupation of Poland with his parents when he was eight and spent much of his youth in Shanghai, where he attended a Jewish school. He emigrated to the United States at age 18. He was married four times, with three marriages ending in divorce. He married Joy Stampler, whose son from a previous relationship died of an opioid overdose in 2003. Joy Stampler Fishman had no idea that naloxone existed or that carrying it would have saved her son, let alone that her current husband had help ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Molecular Biology
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactions. Though cells and other microscopic structures had been observed in living organisms as early as the 18th century, a detailed understanding of the mechanisms and interactions governing their behavior did not emerge until the 20th century, when technologies used in physics and chemistry had advanced sufficiently to permit their application in the biological sciences. The term 'molecular biology' was first used in 1945 by the English physicist William Astbury, who described it as an approach focused on discerning the underpinnings of biological phenomena—i.e. uncovering the physical and chemical structures and properties of biological molecules, as well as their interactions with other molecules and how these interactions explain observ ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Albany Medical Center Prize
The Albany Medical Center Prize in Medicine and Biomedical Research is the United States' second highest value prize in medicine and biomedical research, awarded by the Albany Medical Center. Among prizes for medicine worldwide, the Albany Medical Center Prize is the fourth most lucrative (after the $3 million Breakthrough Prize in Life Sciences, the $1.2 million Nobel Prize in Medicine and the $1 million Shaw Prize in life science and medicine). Awarded annually, the $500,000 prize is bestowed to any physician or scientist, or group, whose work has led to significant advances in the fields of health care and scientific research with demonstrated translational benefits applied to improved patient care. The prize is a legacy to its founder, the late Morris "Marty" Silverman. At the inaugural awards ceremony in Albany, NY in March 2001, Silverman started a tradition that will be carried on for one hundred years, the duration of the Prize. Silverman's promise was to light one can ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Albert Lasker Award For Basic Medical Research
The Albert Lasker Award for Basic Medical Research is one of the Lasker Award, prizes awarded by the Lasker Foundation for a fundamental discovery that opens up a new area of biomedical science. The award frequently precedes a Nobel Prize in Physiology or Medicine, Nobel Prize in Medicine; almost 50% of the winners have gone on to win one. List of recipients See also * List of biomedical science awards Notes {{Reflist Biomedical awards, Lasker Lasker Award ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Gruber Prize In Genetics
The Gruber Prize in Genetics, established in 2001, is one of three international awards worth US$500,000 made by the Gruber Foundation, a non-profit organization based at Yale University in New Haven, Connecticut. The Genetics Prize honors leading scientists for distinguished contributions in any realm of genetics research. The Foundation’s other international prizes are in Cosmology and Neuroscience. Recipients *2001 Rudolf Jaenisch *2002 H. Robert Horvitz *2003 David Botstein *2004 Mary Claire King *2005 Robert Hugh Waterston *2006 Elizabeth Blackburn, a cell biologist specializing in telomeres *2007 Maynard Olson of the University of Washington, a bioinformatics specialist *2008 Allan C. Spradling, PhD, of the Carnegie Institution for Science and Howard Hughes Medical Institute (HHMI) in Baltimore; for his work on fruit fly genomics *2009 Janet Rowley, MD, the Blum-Riese Distinguished Service Professor at thUniversity of Chicago*2010 Gerald Fink, PhD, the Margaret ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Breakthrough Prize In Life Sciences
The Breakthrough Prize in Life Sciences is a scientific award, funded by internet entrepreneurs Mark Zuckerberg and Priscilla Chan of Facebook; Sergey Brin of Google; entrepreneur and venture capitalist Yuri Milner; and Anne Wojcicki, one of the founders of the genetics company 23andMe. The award of $3 million, the largest award in the sciences, is given to researchers who have made discoveries that extend human life. The Prize is awarded annually, beginning in 2013, with six awards given in each subsequent year. Winners are expected to give public lectures and form the committee to decide future winners. The ceremony takes place in the San Francisco Bay Area, with the symposiums alternating between University of California, Berkeley, University of California, San Francisco, and Stanford University. Laureates See also * Breakthrough Prize in Mathematics * Breakthrough Prize in Fundamental Physics * List of biology awards * List of medicine awards This list of medicine aw ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Grand Prix Charles-Leopold Mayer
The Grand Prix Charles-Léopold Mayer (Charles-Léopold Mayer Prize) is awarded annually by the Académie des Sciences (French Academy of Sciences) de l'Institut de France (the French Institute) to researchers who have performed outstanding work in the biological sciences; especially in the areas of cell or molecular biology. Citizens or residents of any nation are eligible for the prize, but it is never awarded to individuals of the same nation two years in a row, nor is the prize ever presented to scholars who are more than 65 years of age. Between the first presentation of the award in 1961 and the year 2009, there have been more than 60 laureates, eleven of whom subsequently received the Nobel Prize in medicine, physiology, or chemistry. The prize is named after French biochemist Charles Léopold Mayer. List of Recipients of the Grand Prix Charles-Léopold Mayer Source Académie des sciences *2019 - Silvia Arber *2018 - Eric Gilson *2016 - Claude Desplan *2015 - François ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |