Charles Blackley
Charles Harrison Blackley (5 April 1820 – 4 September 1900) was the discoverer of the mechanism behind allergic rhinitis caused by pollen Pollen is a powdery substance produced by most types of flowers of seed plants for the purpose of sexual reproduction. It consists of pollen grains (highly reduced Gametophyte#Heterospory, microgametophytes), which produce male gametes (sperm ..., commonly called hay fever. The isolation of hay fever as a condition had been known since 1819 through the work of John Bostock. Blackley was the first to connect pollen to the condition, and though he held some later discredited views, his insight was an important step in the research of allergens. His most important work was a book titled the ''Experimental Researches on the Causes and Nature of Catarrhus aestivus'', published in 1873. Charles Darwin had read this book and wrote to thank him for it. He was very interested in Blackley’s experiments and in another letter explained tha ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bolton
Bolton ( , locally ) is a town in Greater Manchester in England. In the foothills of the West Pennine Moors, Bolton is between Manchester, Blackburn, Wigan, Bury, Greater Manchester, Bury and Salford. It is surrounded by several towns and villages that form the wider Metropolitan Borough of Bolton, borough, of which Bolton is the administrative centre. The town is within the Historic counties of England, historic county boundaries of Lancashire. A former mill town, Bolton has been a centre for textile production since the 14th century when Flemish people, Flemish weavers settled in the area, introducing a wool and cotton-weaving tradition. It was a 19th-century boomtown, development largely coincided with the introduction of textile manufacture during the Industrial Revolution. At its peak in 1929, its 216 cotton mills and 26 bleaching and dyeing works made it one of the largest and most productive centres of Spinning (textiles), cotton spinning in the world. The Brit ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lancashire
Lancashire ( , ; abbreviated ''Lancs'') is a ceremonial county in North West England. It is bordered by Cumbria to the north, North Yorkshire and West Yorkshire to the east, Greater Manchester and Merseyside to the south, and the Irish Sea to the west. The largest settlement is Preston, Lancashire, Preston, and the county town is the city of Lancaster, Lancashire, Lancaster. The county has an area of and a population of 1,490,300. Preston is located near the centre of the county, which is urbanised and includes the towns of Blackburn and Burnley; the seaside resort of Blackpool lies to the west, and Lancaster, Lancashire, Lancaster is in the north. For Local government in England, local government purposes the county comprises a non-metropolitan county, with twelve districts, and two Unitary authorities of England, unitary authority areas: Blackburn with Darwen and Borough of Blackpool, Blackpool. Lancashire County Council and the two unitary councils collaborate through the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ormskirk
Ormskirk is a market town in the West Lancashire district of Lancashire, England. It is located north of Liverpool, northwest of St Helens, Merseyside, St Helens, southeast of Southport and southwest of Preston, Lancashire, Preston. Ormskirk is known for its gingerbread. In 2011 it had a population of 24,073. Geography and administration Ormskirk lies on sloping ground on the side of a ridge, whose highest point is above sea-level, at the centre of the West Lancashire Coastal Plain, West Lancashire Plain, and has been described as a "planned borough", laid out in the 13th century.Lancashire County Council Ormskirk historic town assessment, Lancashire County Council, 2006 Ormskirk is an unparished area, surrounded by the civil parish, parishes of Bickerstaffe, Aughton, Lancash ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Allergic Rhinitis
Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts to allergens in the air. It is classified as a type I hypersensitivity reaction. Signs and symptoms include a runny or stuffy nose, sneezing, red, itchy, and watery eyes, and swelling around the eyes. The fluid from the nose is usually clear. Symptom onset is often within minutes following allergen exposure, and can affect sleep and the ability to work or study. Some people may develop symptoms only during specific times of the year, often as a result of pollen exposure. Many people with allergic rhinitis also have asthma, allergic conjunctivitis, or atopic dermatitis. Allergic rhinitis is typically triggered by environmental allergens such as pollen, pet hair, dust, or mold. Inherited genetics and environmental exposures contribute to the development of allergies. Growing up on a farm and having multiple older siblings ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pollen
Pollen is a powdery substance produced by most types of flowers of seed plants for the purpose of sexual reproduction. It consists of pollen grains (highly reduced Gametophyte#Heterospory, microgametophytes), which produce male gametes (sperm cells). Pollen grains have a hard coat made of sporopollenin that protects the gametophytes during the process of their movement from the stamens to the pistil of flowering plants, or from the male Conifer cone, cone to the female cone of gymnosperms. If pollen lands on a compatible pistil or female cone, it Germination, germinates, producing a pollen tube that transfers the sperm to the ovule containing the female gametophyte. Individual pollen grains are small enough to require magnification to see detail. The study of pollen is called palynology and is highly useful in paleoecology, paleontology, archaeology, and Forensic science, forensics. Pollen in plants is used for transferring Ploidy#Haploid and monoploid, haploid male genetic ma ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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John Bostock (physician)
John Bostock, Jr. FRS (baptised 29 June 1773, died 6 August 1846) was an English physician, scientist and geologist from Liverpool. Life Bostock was a son of Dr. John Bostock, Sr. He spent some time at New College at Hackney where he attended Joseph Priestley's lectures on chemistry and natural philosophy, before graduating in Medicine at the University of Edinburgh and practising medicine in Liverpool. He moved to London in 1817 where he concentrated on general science. In 1819, Bostock was first to accurately describe hay fever as a disease that affected the upper respiratory tract. He lectured on chemistry at Guy's Hospital and was President of the Geological Society of London in 1826 when that body was granted a Royal Charter and Vice President of the Royal Society in 1832. Bostock died of cholera in 1846; He is buried in the Kensal Green Cemetery, London. Works Bostock was one of the first chemical pathologists. He was the first to realise the relationship between th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Charles Harrison Blackley
Charles Harrison Blackley (5 April 1820 – 4 September 1900) was the discoverer of the mechanism behind allergic rhinitis caused by pollen Pollen is a powdery substance produced by most types of flowers of seed plants for the purpose of sexual reproduction. It consists of pollen grains (highly reduced Gametophyte#Heterospory, microgametophytes), which produce male gametes (sperm ..., commonly called hay fever. The isolation of hay fever as a condition had been known since 1819 through the work of John Bostock. Blackley was the first to connect pollen to the condition, and though he held some later discredited views, his insight was an important step in the research of allergens. His most important work was a book titled the ''Experimental Researches on the Causes and Nature of Catarrhus aestivus'', published in 1873. Charles Darwin had read this book and wrote to thank him for it. He was very interested in Blackley’s experiments and in another letter explained tha ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Correspondence Of Charles Darwin
The British naturalist Charles Darwin corresponded with his extended family and with an extraordinarily wide range of people from all over the world. The letters, over 15,000 in all, provide many insights on issues ranging from the origins of key scientific concepts, to religious and philosophical discussions which have continued to the present day. The letters also illuminate many aspects of Darwin and his biography: the development of his ideas; insights into character and health; and private opinions on controversial issues. His letters to the Harvard botanist Asa Gray, for example, show his opinions on slavery and the American Civil War. Darwin relied upon correspondence for much of his scientific work, and also used letters to marshal support for his ideas amongst friends and colleagues. The historian of science Janet Browne has argued that Darwin's ability to correspond daily played a crucial role in the development of his theory and his ability to garner support for it fr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1820 Births
Events January–March *January 1 – A constitutionalist military insurrection at Cádiz leads to the summoning of the Spanish Parliament to meet on March 7, becoming the nominal beginning of the " Trienio Liberal" in Spain. *January 8 – The General Maritime Treaty of 1820 is signed between the sheikhs of Abu Dhabi, Sharjah, Ajman, Umm al-Quwain and Ras Al Khaimah (later constituents of the Trucial States) in the Arabian Peninsula and the United Kingdom. *January 27 ( NS, January 15 OS) – An Imperial Russian Navy expedition, led by Fabian Gottlieb von Bellingshausen in '' Vostok'' with Mikhail Petrovich Lazarev, sights the Antarctic ice sheet. *January 29 – George IV of the United Kingdom becomes the new British monarch upon the death his father King George III after 59 years on the throne. The elder George's death ends the 9-year period known as the British Regency. *January 30 – British Royal Navy captain Edward Bransfield, an Irishman, becomes ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1900 Deaths
As of March 1 (Old Style, O.S. February 17), when the Julian calendar acknowledged a leap day and the Gregorian calendar did not, the Julian calendar fell one day further behind, bringing the difference to 13 days until February 28 (Old Style, O.S. February 15), 2100. Summary Political and military The year 1900 was the end of the 19th century and the beginning of the 20th century. Two days into the new year, the United States Secretary of State, U.S. Secretary of State John Hay announced the Open Door Policy regarding Qing dynasty, China, advocating for equal access for all nations to the Chinese market. The 1900 Galveston hurricane, Galveston hurricane would become the List of disasters in the United States by death toll, deadliest natural disaster in United States history, killing between 6,000 and 12,000 people, mostly in and near Galveston, Texas, as well as leaving 10,000 people homeless, destroying 7,000 buildings of all kinds in Galveston. As of 2025, it remains ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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People From Bolton
The term "the people" refers to the public or common mass of people of a polity. As such it is a concept of human rights law, international law as well as constitutional law, particularly used for claims of popular sovereignty. In contrast, a people is any plurality of persons considered as a whole. Used in politics and law, the term "a people" refers to the collective or community of an ethnic group or nation. Concepts Legal Chapter One, Article One of the Charter of the United Nations states that "peoples" have the right to self-determination. Though the mere status as peoples and the right to self-determination, as for example in the case of Indigenous peoples (''peoples'', as in all groups of indigenous people, not merely all indigenous persons as in ''indigenous people''), does not automatically provide for independent sovereignty and therefore secession. Indeed, judge Ivor Jennings identified the inherent problems in the right of "peoples" to self-determination, as i ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |