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Charles-Édouard Brown-Séquard
Charles-Édouard Brown-Séquard FRS (8 April 1817 – 2 April 1894) was a Mauritian physiologist and neurologist who, in 1850, became the first to describe what is now called Brown-Séquard syndrome. Early life Brown-Séquard was born at Port Louis, Mauritius, to an American father and a French mother. He attended the Royal College in Mauritius, and graduated in medicine at Paris in 1846. He then returned to Mauritius with the intention of practising there, but in 1852 he went to the United States. There he was appointed to the faculty of the Medical College of Virginia where he conducted experiments in the basement of the Egyptian Building. He was elected as a member of the American Philosophical Society in 1854. Later life He returned to Paris, and in 1859 he migrated to London, becoming physician to the National Hospital for the Paralysed and Epileptic. There he stayed for about five years, expounding his views on the pathology of the nervous system in numerous lecture ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Port Louis
Port Louis (, ; or , ) is the capital and most populous city of Mauritius, mainly located in the Port Louis District, with a small western part in the Black River District. Port Louis is the country's financial and political centre. It is administered by the Municipal City Council of Port Louis. According to the 2018 census conducted by Statistics Mauritius, the population was 147,066. History Port Louis was used as a harbour by the Dutch settlers from 1606, when they started to refer to the area as ''Harbour of Tortoises''. In 1736, under French government, it became the administrative centre of Mauritius and a major reprovisioning halt for French ships during their passage between Asia and Europe, around the Cape of Good Hope. The Port is named in honour of King Louis XV of France, Louis XV. During this period of French colonization, Mauritius was known as Ile de France. The French governor at that time, Bertrand-François Mahé de La Bourdonnais, contributed to the develop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuropathology
Neuropathology is the study of disease of nervous system tissue, usually in the form of either small surgical biopsies or whole-body autopsies. Neuropathologists usually work in a department of anatomic pathology, but work closely with the clinical disciplines of neurology, and neurosurgery, which often depend on neuropathology for a diagnosis. Neuropathology also relates to forensic pathology because brain disease or brain injury can be related to cause of death. Neuropathology should not be confused with neuropathy, which refers to disorders of the nerves themselves (usually in the peripheral nervous system) rather than the tissues. In neuropathology, the branches of the specializations of nervous system as well as the tissues come together into one field of study. Methodology The work of the neuropathologist consists largely of examining autopsy or biopsy tissue from the brain and spinal cord to aid in diagnosis of disease. In addition to brain and spinal cord, tissues of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Decussation
Decussation is used in biological contexts to describe a crossing (due to the shape of the Roman numeral for ten, an uppercase 'X' (), ). In Latin anatomical terms, the form is used, e.g. . Similarly, the anatomical term Chiasm (anatomy), chiasma is named after the Greek uppercase 'Χ' (Chi (letter), chi). Whereas a decussation refers to a crossing within the central nervous system, various kinds of crossings in the peripheral nervous system are called chiasma. Examples include: * In the brain, where nerve fibers obliquely cross from one lateral side of the brain to the other, that is to say they cross at a level other than their origin. See for examples decussation of pyramids and sensory decussation. In neuroanatomy, the term ''chiasma'' is reserved for crossing of- or within nerves such as in the optic chiasm. * In Botany, botanical phyllotaxis, leaf taxology, the word ''decussate'' describes an opposite leaves, opposite pattern of leaves which has successive pairs at right ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinal Cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal cord is hollow and contains a structure called the central canal, which contains cerebrospinal fluid. The spinal cord is also covered by meninges and enclosed by the neural arches. Together, the brain and spinal cord make up the central nervous system. In humans, the spinal cord is a continuation of the brainstem and anatomically begins at the occipital bone, passing out of the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it tapers to become the cauda equina. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metabolism
Metabolism (, from ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the conversion of food to building blocks of proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of metabolic wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their Structures#Biological, structures, and respond to their environments. The word ''metabolism'' can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the transportation of substances into and between different cells, in which case the above described set of reactions within the cells is called intermediary (or intermediate) metabolism. Metabolic reactions may be categorized as ''catabolic''—the ''breaking down'' of compounds (for example, of glucose to pyruvate by c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society Of London
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the society's president, according to a set of statutes and standing orders. The members of Council and the president are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the Royal Society) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endocrinology
Endocrinology (from ''endocrine system, endocrine'' + ''wikt:-logy#Suffix, -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, human development (biology), growth and development, tissue (biology), tissue function, sleep, digestion, Respiration (physiology), respiration, excretion, mood (psychology), mood, Stress (physiology), stress, lactation, Motor coordination, movement, reproduction, and sensory perception caused by hormones. Specializations include behavioral endocrinology and comparative endocrinology. The endocrine system consists of several glands, all in different parts of the body, that secrete hormones directly into the blood rather than into a Duct (anatomy), duct system. Therefore, endocrine glands are regarde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Placebo Effect
A placebo ( ) can be roughly defined as a sham medical treatment. Common placebos include inert tablets (like sugar pills), inert injections (like saline), sham surgery, and other procedures. Placebos are used in randomized clinical trials to test the efficacy of medical treatments. In a placebo-controlled trial, any change in the control group is known as the ''placebo response'', and the difference between this and the result of no treatment is the ''placebo effect''. Placebos in clinical trials should ideally be indistinguishable from so-called verum treatments under investigation, except for the latter's particular hypothesized medicinal effect. This is to shield test participants (with their consent) from knowing who is getting the placebo and who is getting the treatment under test, as patients' and clinicians' expectations of efficacy can influence results. The idea of a placebo effect was discussed in 18th century psychology, but became more prominent in the 20th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Benjamin Greenblatt
Robert Benjamin Greenblatt (1906–1987) was a Canadian physician and medical researcher specializing in endocrinology who spent almost all of his career at the Medical College of Georgia (MCG); where he pioneered endocrinology as an independent discipline. He was especially known for his work in the development of the sequential oral contraceptive pill and the oral fertility pill. Biography Born in 1906 in Montreal, Canada, Greenblatt attended McGill University in Montreal, where he received his Bachelor of Arts degree in 1928 and his Doctor of Medicine and Master of Surgery degrees in 1932. In 1935, after completing his internship, he joined MCG as a research fellow in pathology and resident in obstetrics and gynecology. In 1937, he was appointed assistant professor of pathology and gynecology, and two years later, he was named professor of experimental medicine. Greenblatt went on to pioneer endocrinology as an independent discipline. In his early years at MCG Greenblatt wor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cimetière Du Montparnasse
Montparnasse Cemetery () is a cemetery in the Montparnasse quarter of Paris, in the city's 14th arrondissement. The cemetery is roughly 47 acres and is the second largest cemetery in Paris. The cemetery has over 35,000 graves, and approximately 1,000 people are buried there each year. The cemetery is the resting place for a variety of individuals including political figures, philosophers, artists, actors, and writers. Additionally, the cemetery contains a number of tombs commemorating those who died in the Franco-Prussian war during the siege of Paris (1870–1871) and the Paris Commune (1871). History The cemetery was created at the beginning of the 19th century in the southern part of the city. At the same time there were cemeteries outside the city limits: Passy Cemetery to the west, Montmartre Cemetery to the north, and Père Lachaise Cemetery to the east. In the 16th century the intersecting roads of Vavin and Raspail were dump areas for rubble and stones from nearby quarr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Collège De France
The (), formerly known as the or as the ''Collège impérial'' founded in 1530 by François I, is a higher education and research establishment () in France. It is located in Paris near La Sorbonne. The has been considered to be France's most prestigious research establishment. It is an associate member of PSL University. Research and teaching are closely linked at the , whose ambition is to teach "the knowledge that is being built up in all fields of literature, science and the arts". Overview As of 2021, 21 Nobel Prize winners and 9 Fields Medalists have been affiliated with the Collège. It does not grant degrees. Each professor is required to give lectures where attendance is free and open to anyone. Professors, about 50 in number, are chosen by the professors themselves, from a variety of disciplines, in both science and the humanities. The motto of the Collège is ''Docet Omnia'', Latin for "It teaches everything"; its goal is to "teach science in the making" and ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Experimental Medicine
An experimental drug is a medicinal product (a drug or vaccine) that has not yet received approval from governmental regulatory authorities for routine use in human or veterinary medicine. A medicinal product may be approved for use in one disease or condition but still be considered experimental for other diseases or conditions. United States In the United States, the body responsible for approval is the Food and Drug Administration (FDA), which must grant the substance Investigational New Drug (IND) status before it can be tested in human clinical trials. IND status requires the drug's sponsor to submit an IND application that includes data from laboratory and animal testing for safety and efficacy. A drug that is made from a living organism or its products undergoes the same approval process but is called a biologics license application (BLA). Biological drugs include antibodies, interleukins, and vaccines. In 2018 federal " Right to Try" laws were enacted in the United State ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
