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Changjoon Justin Lee
Changjoon Justin Lee is an American neuroscientist specializing in the field of glioscience. He served as the Director of Center for Neuroscience at the Korea Institute of Science and Technology and later founded the WCI Center for Functional Connectomics as part of the World Class Institute Program. In 2015, he established the Center for Glia-Neuron Interaction before becoming co-director of the IBS Center for Cognition and Sociality and head of the Cognitive Glioscience Group in 2018. He has been on the editorial boards of the journals ''Molecular Brain'' and '' Molecular Pain'' and is a chief editor of ''Experimental Neurobiology''. Early life and education Born in a rural area of Gimpo City, Lee interacted with the natural world and raised livestock at home which inspired an interest in biology. After completion of middle school, he left South Korea and moved to the US at age 15 and started high school at Rich Central High School, Olympia Fields, Illinois. While under an Illi ...
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Gimpo
Gimpo () is a city in Gyeonggi Province, South Korea. It borders Incheon, with which it shares the South Korean side of the Han River estuary, as well as Seoul and the lesser cities of Paju and Goyang. North Korea is across the Han River. The current mayor is Jeong Hayoung (). The city's population of more than 300,000 is made up of more than 71,000 households. Gimpo International Airport (formerly Kimpo International Airport) used to be located inside the city, but is now part of Seoul. Tertiary educational institutions located in the city include Kimpo College and Joong-ang Seungga University. The city has 27 elementary schools, 12 middle schools, and 8 high schools, including Gimpo Foreign Language High School. Three elementary schools, two middle schools, and two high schools are located in the area of Tongjin. Modern history In 1914, Yangcheon County and Gimpo County were merged. Yangcheon County was separated into two towns (Yangdong and Yangseo). In 1958, Yeouido Int ...
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Albert Einstein
Albert Einstein ( ; ; 14 March 1879 – 18 April 1955) was a German-born theoretical physicist, widely acknowledged to be one of the greatest and most influential physicists of all time. Einstein is best known for developing the theory of relativity, but he also made important contributions to the development of the theory of quantum mechanics. Relativity and quantum mechanics are the two pillars of modern physics. His mass–energy equivalence formula , which arises from relativity theory, has been dubbed "the world's most famous equation". His work is also known for its influence on the philosophy of science. He received the 1921 Nobel Prize in Physics "for his services to theoretical physics, and especially for his discovery of the law of the photoelectric effect", a pivotal step in the development of quantum theory. His intellectual achievements and originality resulted in "Einstein" becoming synonymous with "genius". In 1905, a year sometimes described as his ...
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Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term memory, remembering recent events. As the disease advances, symptoms can include primary progressive aphasia, problems with language, Orientation (mental), disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and challenging behaviour, behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years. The cause of Alzheimer's disease is poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an alle ...
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Monoamine Oxidase B
Monoamine oxidase B, also known as MAOB, is an enzyme that in humans is encoded by the ''MAOB'' gene. The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is an enzyme located in the outer mitochondrial membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the catabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (such as dopamine). This protein preferentially degrades benzylamine and phenethylamine. Similarly to monoamine oxidase A (MAOA), it also degrades dopamine hough some new research contradicts this, suggesting that MAOB does ''not'' directly degrade dopamine, but is responsible for GABA synthesis Structure Monoamine oxidase B has a hydrophobic bipartite elongated cavity that (for the "open" conformation) occupies a combined volume close to 700 Å3. h MAO-A has a single cavity that exhibits a rounder shape and is larger in volum ...
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Glutamic Acid
Glutamic acid (symbol Glu or E; the ionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins. It is a non-essential nutrient for humans, meaning that the human body can synthesize enough for its use. It is also the most abundant excitatory neurotransmitter in the vertebrate nervous system. It serves as the precursor for the synthesis of the inhibitory gamma-aminobutyric acid (GABA) in GABA-ergic neurons. Its molecular formula is . Glutamic acid exists in three optically isomeric forms; the dextrorotatory -form is usually obtained by hydrolysis of gluten or from the waste waters of beet-sugar manufacture or by fermentation.Webster's Third New International Dictionary of the English Language Unabridged, Third Edition, 1971. Its molecular structure could be idealized as HOOC−CH()−()2−COOH, with two carboxyl groups −COOH and one amino group −. However, in the solid state and mildly acidic water sol ...
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Gliotransmitter
Gliotransmitters are chemicals released from glial cells that facilitate neuronal communication between neurons and other glial cells. They are usually induced from Ca2+ signaling, although recent research has questioned the role of Ca2+ in gliotransmitters and may require a revision of the relevance of gliotransmitters in neuronal signalling in general. While gliotransmitters can be released from any glial cell, including oligodendrocytes, astrocytes, and microglia, they are primarily released from astrocytes. Astrocytes rely on gap junctions for coupling, and are star-like in shape, which allows them to come into contact with many other synapses in various regions of the brain. Their structure also makes them capable of bidirectional signaling. It is estimated that astrocytes can make contact with over 100,000 synapses, allowing them to play an essential role in synaptic transmission. While gliotransmission primarily occurs between astrocytes and neurons, gliotransmission i ...
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Korea University
Korea University (KU, ) is a private research university in Seoul, South Korea, established in 1905. The university is included as one of the SKY universities, a popular acronym referring to Korea's three most prestigious universities. The student body consists of over 20,000 undergraduate students and over 10,000 graduate students. The university has 81 departments in 19 colleges and divisions, as well as 18 graduate schools. It has over 1,500 full-time faculty members with over 95% of them holding Ph.D. or equivalent qualification in their field. The Korea University Alumni Association consists of more than 280,000 university graduates. Korea University is a large research institution, notable in South Korean history for being the first educational institution to offer academic programs in Korea in various disciplines, such as law, economics and journalism. It is particularly well known for its College of Law. Korea University also has auxiliary educational facilitie ...
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Korea University Of Science And Technology
The University of Science and Technology (UST) is a group of public universities and research institutions in Seoul, Suwon, Changwon, Ansan, Seongnam and Daejeon, in South Korea. The UST was established in 2003 by the Ministry of Science, ICT and Future Planning as the nation’s graduate school specializing in science and engineering education and research. The UST runs only a graduate school. Creating the new driving force for growth would play a major role in leading national growth in the new century. The South Korean government established the UST to produce professionals in the field of combined technologies, thought of as one of the most important criteria for creating the driving force for South Korea's national growth. Today, UST continues to develop itself into a major research university. Education advantages UST established courses that allow students to build experience in research fields. Lab rotation is an example. UST encourage students to get hands-on experience ...
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Protease-activated Receptor
Protease-activated receptors (PAR) are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular domain. They are highly expressed in platelets, and also on endothelial cells, myocytes and neurons. Protease-activated receptors PAR are not to be mistaken with PAR proteins, a group of regulators of cellular polarity named after their associated partitioning phenotype. Classification There are four mammalian members of the protease-activated receptor (PAR) family: PAR1 - encoded by the gene F2R, PAR2 - F2RL1, PAR3 - F2RL2 and PAR4 - F2RL3, all these genes have their locus on chromosome 5 except of PAR4, which is on chromosome 19. They are also members of the seven-transmembrane G-protein-coupled receptor superfamily, and are expressed throughout the body. History PAR1 was firstly described in 1991 on human platelets as a thrombin receptor. In 1994 another member of this family was discovered, S. Nystedt named it simp ...
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Olympia Fields, Illinois
Olympia Fields is a village and a south suburb of Chicago in Cook County, Illinois, United States. The population was 4,718 as of the 2020 census. The municipality grew up around the prestigious Olympia Fields Country Club, originally established in 1915. Olympia Fields is noteworthy as one of the wealthiest and best educated, majority African-American communities in the United States. The village's zip code (60461) is one of three majority African American communities which rank among the top five percent in the U.S. for median household income and share of adults with college degrees, and Olympia Fields also has the highest black homeownership rate in the country among majority-black municipalities. History The area that comprises the village today was once farmland managed by immigrant families during the 1830s. The Illinois Central Railroad began serving the area in the 1850s, which fostered population and economic growth during that era. In 1893, the Columbian Expositio ...
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Rich Central High School
Rich Township High School STEM Campus, formerly Rich Central High School, is a public four-year high school in the south suburbs of Chicago, located in Olympia Fields, Illinois. The Campus serves portions of Chicago Heights, Country Club Hills, Matteson, Olympia Fields, Park Forest, Richton Park, and Tinley Park. The school serves sections of elementary school districts 162, 161, 160, and 159. It is a part of Rich Township District 227, along with Rich Township Fine Arts Campus. History Rich Township High School District #227 serves the residents of Country Club Hills, Matteson, parts of Olympia Fields, Park Forest, Richton Park, a small section of Chicago Heights, and adjoining rural areas in South Cook County. The district was formed from non-high-school territory in 1949. Construction of the East Campus of Rich Township High School, financed by a $1,600,000 bond issue, began in September 1952. Twelve months later, it was operating as a four-year high school. During the 195 ...
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Molecular Pain
''Molecular Pain'' is a peer-reviewed open access medical journal covering all aspects of research on pain. It was established in 2005 and is published by BioMed Central. The editors-in-chief are Jianguo Gu (University of Alabama at Birmingham) and Min Zhuo (University of Toronto), who was also the founding editor of the journal. It is sponsored by the University of Cincinnati College of Medicine. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2012 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 3.774. References External links * {{Official website, http://www.molecularpain.com/ Neuroscience journals Anesthesiology and palliative medicine journals BioMed Central acad ...
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