Chain Ejection Model
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Chain Ejection Model
Electrospray ionization (ESI) is a technique used in mass spectrometry to produce ions using an electrospray in which a high voltage is applied to a liquid to create an aerosol. It is especially useful in producing ions from macromolecules because it overcomes the propensity of these molecules to fragment when ionized. ESI is different from other ionization processes (e.g. matrix-assisted laser desorption/ionization, MALDI) since it may produce multiple-charged ions, effectively extending the mass range of the analyser to accommodate the kDa-MDa orders of magnitude observed in proteins and their associated polypeptide fragments. Mass spectrometry using ESI is called electrospray ionization mass spectrometry (ESI-MS) or, less commonly, electrospray mass spectrometry (ES-MS). ESI is a so-called 'soft ionization' technique, since there is very little fragmentation. This can be advantageous in the sense that the molecular ion (or more accurately a pseudo molecular ion) is almost alw ...
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John Zeleny
John Zeleny (March 26, 1872 – June 19, 1951) was an American physicist who, in 1911, invented the Zeleny electroscope. He also studied the effect of an electric field on a liquid meniscus. His work is seen by some as a beginning to emergent technologies like liquid metal ion sources and electrospraying and electrospinning. Zeleny was born in Racine, Wisconsin to a Czech immigrant couple from Křídla. He was the older brother of Charles Zeleny. He attended the University of Minnesota (B.S., 1892), followed by Trinity College, Cambridge (B.A., 1899), and the University of Minnesota (PhD, 1906). Zeleny began his teaching career at the University of Minnesota after earning his B.A. in 1892. Zeleny was an elected member of the American Academy of Arts and Sciences. He was elected to the American Philosophical Society The American Philosophical Society (APS) is an American scholarly organization and learned society founded in 1743 in Philadelphia that promotes knowledge ...
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Field Desorption
Field desorption (FD) is a method of ion formation used in mass spectrometry (MS) in which a high-potential electric field is applied to an ''emitter'' with a sharp surface, such as a razor blade, or more commonly, a filament from which tiny "whiskers" have formed. This results in a high electric field which can result in ionization of gaseous molecules of the analyte. Mass spectra produced by FD have little or no fragmentation because FD is a soft ionization method. They are dominated by molecular radical cations M+. and less often, protonated molecules H. The technique was first reported by Beckey in 1969.Beckey H.D. ''Field ionization mass spectrometry.'' Research/Development, ''1969'', 20(11), 26 It is also the first ionization method to ionize nonvolatile and thermally labile compounds. One major difference of FD with other ionization methods is that it does not need a primary beam to bombard a sample. Mechanism In FD, the analyte is applied as a thin film directly to the ...
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Nitrogen
Nitrogen is a chemical element; it has Symbol (chemistry), symbol N and atomic number 7. Nitrogen is a Nonmetal (chemistry), nonmetal and the lightest member of pnictogen, group 15 of the periodic table, often called the Pnictogen, pnictogens. It is a common element in the universe, estimated at Abundance of the chemical elements, seventh in total abundance in the Milky Way and the Solar System. At standard temperature and pressure, two atoms of the element chemical bond, bond to form N2, a colourless and odourless diatomic molecule, diatomic gas. N2 forms about 78% of Atmosphere of Earth, Earth's atmosphere, making it the most abundant chemical species in air. Because of the volatility of nitrogen compounds, nitrogen is relatively rare in the solid parts of the Earth. It was first discovered and isolated by Scottish physician Daniel Rutherford in 1772 and independently by Carl Wilhelm Scheele and Henry Cavendish at about the same time. The name was suggested by French chemist ...
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Nebulizer
In medicine, a nebulizer (American English) or nebuliser (English language, English) is a drug delivery device used to administer medication in the form of a mist inhaled into the lungs. Nebulizers are commonly used for the treatment of asthma, cystic fibrosis, COPD and other respiratory diseases or disorders. They use oxygen, compressed air or ultrasonics, ultrasonic power to break up solutions and suspensions into small aerosol droplets that are inhaled from the mouthpiece of the device. An aerosol is a mixture of gas and solid or liquid particles. Medical uses Guidelines Various asthma guidelines, such as the Global Initiative for Asthma Guidelines [GINA], the British Guidelines on the management of Asthma, The Canadian Pediatric Asthma Consensus Guidelines, and United States Guidelines for Diagnosis and Treatment of Asthma each recommend metered dose inhalers in place of nebulizer-delivered therapies. The European Respiratory Society acknowledge that although nebulizers are ...
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Volatile Organic Compound
Volatile organic compounds (VOCs) are organic compounds that have a high vapor pressure at room temperature. They are common and exist in a variety of settings and products, not limited to Indoor mold, house mold, Upholstery, upholstered furniture, Handicraft, arts and crafts supplies, Dry cleaning, dry cleaned clothing, and Cleaning agent, cleaning supplies. VOCs are responsible for the odor of scents and perfumes as well as pollutants. They play an important role in communication between animals and plants, such as attractants for pollinators, protection from predation, and even inter-plant interactions. Some VOCs are dangerous to human health or cause harm to the natural environment, environment, often despite the odor being perceived as pleasant, such as "new car smell". Human impact on the environment, Anthropogenic VOCs are regulated by law, especially indoors, where concentrations are the highest. Most VOCs are not acutely toxic, but may have long-term chronic health effect ...
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Electrospray
The name electrospray is used for an apparatus that employs electricity to disperse a liquid or for the fine aerosol resulting from this process. High voltage is applied to a liquid supplied through an emitter (usually a glass or metallic capillary). Ideally the liquid reaching the emitter tip forms a Taylor cone, which emits a liquid jet through its apex. Varicose waves on the surface of the jet lead to the formation of small and highly charged liquid droplets, which are radially dispersed due to Coulomb's law, Coulomb repulsion. History In the late 16th century William Gilbert (astronomer), William Gilbert set out to describe the behaviour of magnetic and electrostatic phenomena. He observed that, in the presence of a charged piece of amber, a drop of water deformed into a cone. This effect is clearly related to electrosprays, even though Gilbert did not record any observation related to liquid dispersion under the effect of the electric field. In 1750 the French clergyman and ...
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Fenn ESI Instrument
Fenn typically appears as a surname. Occasionally it appears as a middle name, pen name or name of a fictional character. Notable people with the name Fenn As a surname * Augustus H. Fenn (1844–1897), justice of the Connecticut Supreme Court * Courtenay Hughes Fenn (1866–1927), American-Chinese Presbyterian missionary and father of Henry Courtenay Fenn * Darren Fenn (born 1980), basketball player * E. Hart Fenn (1856–1939), American national politician * Ellenor Fenn (1743–1813), English writer * George Manville Fenn (1831–1909), English author * Geraldine Fenn (1912–1989), American professor * Harry Fenn (1845–1911), English-American landscape illustrator * Henry Courtenay Fenn (1894–1978), Chinese-American academic and son of Courtenay Hughes Fenn * Hugh Fenn (died 1409), English official from Norfolk who served under Richard II and Henry IV * Hugh Fenn (died 1476), English official from Norfolk who served under Henry VI and Edw ...
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Journal Of Chemical Physics
''The Journal of Chemical Physics'' is a scientific journal published by the American Institute of Physics that carries research papers on chemical physics."About the Journal"
from the ''Journal of Chemical Physics'' website.
Two volumes, each of 24 issues, are published annually. It was established in 1933 when '''' editors refused to publish theoretical works. The editors have been: *2019–present: Tim Lian *2008–2018: Marsha I. Lester *2007–2008:
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Malcolm Dole
Malcolm Dole (March 4, 1903 – November 29, 1990) was an American chemist known for the Dole Effect in which he proved that the atomic weight of oxygen in air is greater than that of oxygen in water and for his work on electrospray ionization, polymer chemistry, and electrochemistry. Dole effect The Dole effect is the inequality in the ratio of heavy oxygen isotope 18O to the more abundant 16O in the Earth's atmosphere and in seawater. This effect was reported by Dole in 1935. The effect is due to slightly different reaction rates for the two isotopes in respiration in plants and in animals which tends to retain the lighter 16O, which increases the relative concentration of 18O in the atmosphere. The effect has also been linked to hydrologic processes, such as the enrichment of the lighter 16O as water vapor is transported poleward. Electrospray Electrospray is a process in which a high voltage is applied to a liquid to create an aerosol containing highly charged dro ...
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Proceedings Of The Royal Society A
''Proceedings of the Royal Society'' is the main research journal of the Royal Society. The journal began in 1831 and was split into two series in 1905: * Series A: for papers in physical sciences and mathematics. * Series B: for papers in life sciences. Many landmark scientific discoveries are published in the Proceedings, making it one of the most important science journals in history. The journal contains several articles written by prominent scientists such as Paul Dirac, Werner Heisenberg, Ernest Rutherford, Erwin Schrödinger, William Lawrence Bragg, Lord Kelvin, J.J. Thomson, James Clerk Maxwell, Dorothy Hodgkin and Stephen Hawking. In 2004, the Royal Society began '' The Journal of the Royal Society Interface'' for papers at the interface of physical sciences and life sciences. History The journal began in 1831 as a compilation of abstracts of papers in the '' Philosophical Transactions of the Royal Society'', the older Royal Society publication, that began in ...
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