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Catherine Llorens-Cortes
Catherine Llorens-Cortès (née Lepart; born January 6, 1954) is a French pharmacologist who is a Professor and Director of the Central Laboratory of Neuropeptides and Water and Cardiovascular Regulations at the Collège de France. Her research considers neuropharmacology and the development of new therapies for people with heart conditions. She was awarded the French Academy of Sciences Medal for Applications of Science in 2023. Early life and education Llorens-Cortès was born in Saint-Germain-en-Laye. She was a doctoral researcher at the Pierre and Marie Curie University, where she studied endorphin recognition and response to morphine. After earning her doctorate she was appointed to a permanent research position at L'Institut national de la santé et de la recherche médicale (INSERM), where she eventually became research director. Research and career Llorens-Cortès has been interested in biologically active peptides since the start of her career. She has mainly worke ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
INSERM
The (Inserm, ) is the French National Institute of Health and Medical Research. History and organisation Inserm was created in 1964 as a successor to the French National Institute of Health. Inserm is the only public research institution solely focused on human health and medical research in France. It is a public institution with a scientific and technical vocation under the dual auspices of the Ministry of Health and the Ministry of Research. Similarly to the US National Institutes of Health, Inserm conducts fundamental and translational research projects through 339 research units, run by around 13,000 scientists, including 5,100 permanent research staff members and 5,100 staff members co-affiliated with university hospitals and medicine faculties. Inserm's laboratories and research units are located all over France, mainly in the largest cities. Eighty percent of Inserm research units are embedded in research hospitals of French universities. In 1997, Inserm founded ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Left Ventricular Dysfunction
{{disambiguation ...
Left may refer to: Music * ''Left'' (Hope of the States album), 2006 * ''Left'' (Monkey House album), 2016 * ''Left'' (Helmet album), 2023 * "Left", a song by Nickelback from the album ''Curb'', 1996 Direction * Left (direction), the relative direction opposite of right * Left-handedness Politics * Left (Austria), a movement of Marxist–Leninist, Maoist and Trotskyist organisations in Austria * Left-wing politics (also known as left or leftism), a political trend or ideology ** Centre-left politics ** Far-left politics * The Left (Germany) See also * Copyleft * Leaving (other) * Lefty (other) * Sinister (other) * Venstre (other) * Right (other) A right is a legal or moral entitlement or permission. Right or rights may also refer to: * Right, synonym of true or accurate, opposite of wrong * Morally right, opposite of morally wrong * Right (direction), the relative direction opposite of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Saint-Germain-en-Laye
The term "the people" refers to the public or common mass of people of a polity. As such it is a concept of human rights law, international law as well as constitutional law, particularly used for claims of popular sovereignty. In contrast, a people is any plurality of persons considered as a whole. Used in politics and law, the term "a people" refers to the collective or community of an ethnic group or nation. Concepts Legal Chapter One, Article One of the Charter of the United Nations states that "peoples" have the right to self-determination. Though the mere status as peoples and the right to self-determination, as for example in the case of Indigenous peoples (''peoples'', as in all groups of indigenous people, not merely all indigenous persons as in ''indigenous people''), does not automatically provide for independent sovereignty and therefore secession. Indeed, judge Ivor Jennings identified the inherent problems in the right of "peoples" to self-determination, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French Pharmacologists
French may refer to: * Something of, from, or related to France ** French language, which originated in France ** French people, a nation and ethnic group ** French cuisine, cooking traditions and practices Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), a 2008 film * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a type of military jacket or tunic * French's, an American brand of mustard condiment * French (catheter scale), a unit of measurement * French Defence, a chess opening * French kiss, a type of kiss See also * France (other) * Franch, a surname * French Revolution (other) * French River (other), several rivers and other places * Frenching (other) * Justice French (other) Justice French may refer to: * C. G. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academic Staff Of The Collège De France
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of tertiary education. The name traces back to Plato's school of philosophy, founded approximately 386 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and Skills, skill, north of Ancient Athens, Athens, Greece. The Royal Spanish Academy defines academy as scientific, literary or artistic society established with public authority and as a teaching establishment, public or private, of a professional, artistic, technical or simply practical nature. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the Gymnasium (ancient Greece), gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive Grove (nature), grove, hence the expression "the groves of Academe". In these gardens, the philos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1954 Births
Events January * January 3 – The Italian broadcaster RAI officially begins transmitting. * January 7 – Georgetown–IBM experiment: The first public demonstration of a machine translation system is held in New York, at the head office of IBM. * January 10 – BOAC Flight 781, a de Havilland Comet jet plane, disintegrates in mid-air due to metal fatigue, and crashes in the Mediterranean near Elba; all 35 people on board are killed. * January 12 – 1954 Blons avalanches, Avalanches in Austria kill more than 200. * January 15 – Mau Mau rebellion, Mau Mau leader Waruhiu Itote is captured in Kenya. * January 17 – In Socialist Federal Republic of Yugoslavia, Yugoslavia, Milovan Đilas, one of the leading members of the League of Communists of Yugoslavia, is relieved of his duties. * January 20 – The US-based National Negro Network is established, with 46 member radio stations. * January 21 – The first nuclear-powered submarine, the , is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legion Of Honour
The National Order of the Legion of Honour ( ), formerly the Imperial Order of the Legion of Honour (), is the highest and most prestigious French national order of merit, both military and Civil society, civil. Currently consisting of five classes, it was originally established in 1802 by Napoleon, Napoleon Bonaparte, and it has been retained (with occasional slight alterations) by all later French governments and regimes. The order's motto is ' ("Honour and Fatherland"); its Seat (legal entity), seat is the Palais de la Légion d'Honneur next to the Musée d'Orsay, on the left bank of the Seine in Paris. Since 1 February 2023, the Order's grand chancellor has been retired General François Lecointre, who succeeded fellow retired General Benoît Puga in office. The order is divided into five degrees of increasing distinction: ' (Knight), ' (Officer), ' (Commander (order), Commander), ' (Grand Officer) and ' (Grand Cross). History Consulate During the French Revolution, all ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apelin
Apelin (also known as APLN) is a peptide that in humans is encoded by the ''APLN'' gene. Apelin is one of two endogenous ligands for the G-protein-coupled APJ receptor that is expressed at the surface of some cell types. It is widely expressed in various organs such as the heart, lung, kidney, liver, adipose tissue, gastrointestinal tract, brain, adrenal glands, endothelium, and human plasma. Discovery Apelin is a peptide hormone that was identified in 1998 by Masahiko Fujino and his colleagues at Gunma University and Takeda Pharmaceutical Company. In 2013, a second peptide hormone named Elabela was found by Bruno Reversade to also act as an endogenous ligand to the APLNR. Biosynthesis The apelin gene encodes a pre-proprotein of 77 amino acids, with a signal peptide in the N-terminal region. After translocation into the endoplasmic reticulum and cleavage of the signal peptide, the proprotein of 55 amino acids may generate several active fragments: a 36 amino acid pepti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myocardial Infarction
A myocardial infarction (MI), commonly known as a heart attack, occurs when Ischemia, blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle. The most common symptom is retrosternal Angina, chest pain or discomfort that classically radiates to the left shoulder, arm, or jaw. The pain may occasionally feel like heartburn. This is the dangerous type of acute coronary syndrome. Other symptoms may include shortness of breath, nausea, presyncope, feeling faint, a diaphoresis, cold sweat, Fatigue, feeling tired, and decreased level of consciousness. About 30% of people have atypical symptoms. Women more often present without chest pain and instead have neck pain, arm pain or feel tired. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an Cardiac arrhythmia, irregular heartbeat, cardiogenic shock or cardiac arrest. Most MIs occur d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Firibastat
Firibastat is a prodrug A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. Instead of administering a drug directly, a corresponding prodrug can be ... of two brain aminopeptidase A inhibitors, developed to treat resistant hypertension. It failed to show efficacy in a Phase III trial. References {{reflist Prodrugs Antihypertensive agents Sulfonic acids Diamines Organic disulfides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Collège De France
The (), formerly known as the or as the ''Collège impérial'' founded in 1530 by François I, is a higher education and research establishment () in France. It is located in Paris near La Sorbonne. The has been considered to be France's most prestigious research establishment. It is an associate member of PSL University. Research and teaching are closely linked at the , whose ambition is to teach "the knowledge that is being built up in all fields of literature, science and the arts". Overview As of 2021, 21 Nobel Prize winners and 9 Fields Medalists have been affiliated with the Collège. It does not grant degrees. Each professor is required to give lectures where attendance is free and open to anyone. Professors, about 50 in number, are chosen by the professors themselves, from a variety of disciplines, in both science and the humanities. The motto of the Collège is ''Docet Omnia'', Latin for "It teaches everything"; its goal is to "teach science in the making" and ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
