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Carl Faingold
Carl L. Faingold is an American neuroscientist and professor in the Department of Pharmacology of Southern Illinois University School of Medicine in Springfield, Illinois. He is a founding faculty member of both the department and the School of Medicine. He has had an extensive career as a medical and graduate student educator and as a researcher in brain mechanisms. He is a specialist in the actions of drugs on brain activity at the level of the single neuron as it relates to networks of neurons in awake behaving animals. Education Faingold received a B.S. in pharmacy from the University of Illinois at Chicago in 1965, and a Ph.D. in pharmacology from Northwestern University in 1970. This was followed by a postdoctoral fellowship at the University of Missouri Institute of Psychiatry. Research interests A major research direction in Faingold's lab is in the area of sudden unexpected death in epilepsy (SUDEP), which is a devastating and relatively rare problem that can occur i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacology
Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, functions, sources, synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics. Pharmacodynamics studies the effects of a drug on biological systems, and pharmacokinetics studies the effects of biological systems on a drug. In broad terms, pharmacod ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Southern Illinois University School Of Medicine
Southern Illinois University School of Medicine is a medical school located in Springfield, the capital of the U.S. state of Illinois. It is part of the Southern Illinois University system, which includes a campus in Edwardsville as well as the flagship in Carbondale. The medical school was founded in 1970 and achieved full accreditation in 1972. It was founded to relieve a chronic shortage of physicians in downstate Illinois. Notability SIU was once the only medical school in Illinois with its main campus outside of Chicago or its suburbs until the Carle Illinois College of Medicine was formed in 2018 (although the University of Illinois at Chicago does maintain satellites in Peoria and Rockford). SIU was early to incorporate problem-based learning (PBL) into their curricula (see below) and "standardized patients" for medical student testing purposes. SIU students begin care of patients in a clinical setting within the first two weeks of classes. By the end of their ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Illinois At Chicago
The University of Illinois Chicago (UIC) is a public research university in Chicago, Illinois, United States. Its campus is in the Near West Side community area, adjacent to the Chicago Loop. The second campus established under the University of Illinois system, UIC is also the largest university in the Chicago metropolitan area, having more than 33,000 students enrolled in 16 colleges. It is classified among "R1: Doctoral Universities – Very high research activity." UIC competes in NCAA Division I Missouri Valley Conference. History Beginnings The University of Illinois Chicago traces its origins to several health colleges founded during the late 19th century, including the Chicago College of Pharmacy, which opened in 1859, the College of Physicians and Surgeons (1882), and the Columbian College of Dentistry (1893). The University of Illinois was chartered in 1867 in Champaign-Urbana, as the state's land-grant university. In exchange for agreeing to the Champaign-Ur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Northwestern University
Northwestern University (NU) is a Private university, private research university in Evanston, Illinois, United States. Established in 1851 to serve the historic Northwest Territory, it is the oldest University charter, chartered university in Illinois. Chartered by the Illinois General Assembly in 1851, Northwestern was initially affiliated with the Methodist Episcopal Church but later became non-sectarian. By 1900, the university was the third-largest Higher education in the United States, university in the United States, after University of Michigan, Michigan and Harvard University, Harvard. Northwestern became a founding member of the Big Ten Conference in 1896 and joined the Association of American Universities in 1917. Northwestern is composed of eleven undergraduate, graduate, and professional schools in the fields of Kellogg School of Management, management, Pritzker School of Law, law, Medill School of Journalism, journalism, McCormick School of Engineering, enginee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Missouri
The University of Missouri (Mizzou or MU) is a public university, public Land-grant university, land-grant research university in Columbia, Missouri, United States. It is Missouri's largest university and the flagship of the four-campus University of Missouri System. Founded in 1839, MU was the first public university west of the Mississippi River. It has been a member of the Association of American Universities since 1908 and is classified among "R1: Doctoral Universities – Very high research activity." Enrolling 31,041 students in 2023, it offers more than 300 degree programs in thirteen major academic divisions. Its Missouri School of Journalism, founded by Walter Williams (journalist), Walter Williams in 1908, was established as the world's first journalism school; it publishes a daily newspaper, the ''Columbia Missourian'', and operates NBC affiliate KOMU-TV, KOMU. The University of Missouri Research Reactor Center is the sole source of isotopes in nuclear medicine in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sudden Unexpected Death In Epilepsy
Sudden Unexpected Death in Epilepsy (SUDEP) refers to the sudden, unexpected death of a person with epilepsy that is not the result of trauma, drowning, or an identified medical condition. In most cases, no structural or toxicological cause of death is found at autopsy. SUDEP can occur with or without evidence of a preceding seizure, and is often unwitnessed, especially during sleep. The exact mechanisms underlying SUDEP remain unclear but are believed to be multifactorial. Potential contributors include seizure-related disruptions in breathing, heart rhythm, or brain function, often in combination. SUDEP is estimated to affect approximately 1 in 1,000 adults and 1 in 4,500 children with epilepsy each year. It accounts for 7% to 17% of epilepsy-related deaths overall, and up to 50% in those with refractory epilepsy. Deaths caused by status epilepticus or accidents such as drowning are classified separately. Definition To improve consistency in clinical reporting and resear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serotonin
Serotonin (), also known as 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter with a wide range of functions in both the central nervous system (CNS) and also peripheral tissues. It is involved in mood, cognition, reward, learning, memory, and physiological processes such as vomiting and vasoconstriction. In the CNS, serotonin regulates mood, appetite, and sleep. Most of the body's serotonin—about 90%—is synthesized in the gastrointestinal tract by enterochromaffin cells, where it regulates intestinal movements. It is also produced in smaller amounts in the brainstem's raphe nuclei, the skin's Merkel cells, pulmonary neuroendocrine cells, and taste receptor cells of the tongue. Once secreted, serotonin is taken up by platelets in the blood, which release it during clotting to promote vasoconstriction and platelet aggregation. Around 8% of the body's serotonin is stored in platelets, and 1–2% is found in the CNS. Serotonin acts as both a vasoconstrictor and vas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adenosine
Adenosine (symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives. The molecule consists of an adenine attached to a ribose via a β-N9- glycosidic bond. Adenosine is one of the four nucleoside building blocks of RNA (and its derivative deoxyadenosine is a building block of DNA), which are essential for all life on Earth. Its derivatives include the energy carriers adenosine mono-, di-, and triphosphate, also known as AMP/ADP/ATP. Cyclic adenosine monophosphate (cAMP) is pervasive in signal transduction. Adenosine is used as an intravenous medication for some cardiac arrhythmias. Adenosyl (abbreviated Ado or 5'-dAdo) is the chemical group formed by removal of the 5′-hydroxy (OH) group. It is found in adenosylcobalamin (an active form of vitamin B12) and as a radical in the radical SAM enzymes. Medical uses Supraventricular tachycardia In individuals with supraventricular tachycardia (SVT), adenosine is a first line trea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Selective Serotonin Reuptake Inhibitors
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs primarily work by blocking serotonin reabsorption (reuptake) via the serotonin transporter, leading to gradual changes in brain signaling and receptor regulation, with some also interacting with sigma-1 receptors, particularly fluvoxamine, which may contribute to cognitive effects. Marketed SSRIs include six main antidepressants—citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline—while dapoxetine is indicted for premature ejaculation. Fluoxetine has been approved for veterinary use in treatment of canine separation anxiety. SSRIs are the most widely prescribed antidepressants in many countries. Their effectiveness, especially for mild to moderate depression, remains debated due to mixed research findings and concerns abou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hal Blumenfeld
Hal Blumenfeld (born March 28, 1962) is a professor of neurology, neuroscience, and neurosurgery at Yale University. His focus is on brain mechanisms of consciousness and on altered consciousness in epilepsy. As director of the Yale Clinical Neuroscience Imaging Center, he leads multi-disciplinary research and is also well known for his teaching contributions in neuroanatomy and clinical neuroscience. Biography Blumenfeld was born in California, grew up in New York and began his career in Bio-electrical Engineering at Harvard University (1984).Curriculum Vitae. Blumenfeld, H. (Accessed 20 May 2021). https://prod.admin.profile.yale.edu/Profiles/Cv/user/hal_blumenfeld His passion for science would lead him to Columbia University where, working with Eric Kandel and Steven Siegelbaum, he obtained his PhD (1990) in Physiology and Cellular Biophysics and his MD (1992). He completed his internal medicine internship at Columbia Presbyterian Medical Center(1993) and entered the field of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Year Of Birth Missing (living People)
A year is a unit of time based on how long it takes the Earth to orbit the Sun. In scientific use, the tropical year (approximately 365 solar days, 5 hours, 48 minutes, 45 seconds) and the sidereal year (about 20 minutes longer) are more exact. The modern calendar year, as reckoned according to the Gregorian calendar, approximates the tropical year by using a system of leap years. The term 'year' is also used to indicate other periods of roughly similar duration, such as the lunar year (a roughly 354-day cycle of twelve of the Moon's phasessee lunar calendar), as well as periods loosely associated with the calendar or astronomical year, such as the seasonal year, the fiscal year, the academic year, etc. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by changes in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
