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CTD JCaison
CTD may refer to: Medicine * Carnitine transporter deficiency, an inborn error of fatty acid transport * Comparative Toxicogenomics Database, an online research tool describing chemical-gene-disease interactions * CTD (chemotherapy), a combination of the drugs cyclophosphamide, thalidomide, and dexamethasone * Common Technical Document, an internationally agreed format for drug approvals * Connective tissue disease * Circling the Drain, acronym relating to those on the way out Music *Crash Test Dummies, a Canadian rock band from Winnipeg, Manitoba Science * Comparative Toxicogenomics Database, an online research tool describing chemical-gene-disease interactions * CTD (instrument), in oceanography, used to determine conductivity, temperature, and depth * Carboxy-Terminal Domain, the end of an amino acid chain which has specialized functions in some proteins * Church–Turing–Deutsch principle, in computer science, relates to the universality of simulation IT (Information T ...
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Carnitine Transporter Deficiency
Systemic primary carnitine deficiency (SPCD)Systemic primary carnitine deficiency
is an inborn error of fatty acid transport caused by a defect in the transporter responsible for moving across the . Carnitine is an important amino acid for fatty acid metabolism. When carnitine cann ...
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Comparative Toxicogenomics Database
The Comparative Toxicogenomics Database (CTD) is a public website and research tool launched in November 2004 that curates scientific data describing relationships between chemicals/drugs, genes/proteins, diseases, taxa, phenotypes, GO annotations, pathways, and interaction modules. The database is maintained by the Department of Biological Sciences at North Carolina State University. Background The Comparative Toxicogenomics Database (CTD) is a public website and research tool that curates scientific data describing relationships between chemicals, genes/proteins, diseases, taxa, phenotypes, GO annotations, pathways, and interaction modules, launched on November 12, 2004. The database is maintained by the Department of Biological Sciences at North Carolina State University. Goals and objectives One of the primary goals of CTD is to advance the understanding of the effects of environmental chemicals on human health on the genetic level, a field called toxicogenomics. The etiolog ...
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CTD (chemotherapy)
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via cytotoxicity. A fundamental philosophy of medical oncology, including combination chemotherapy, is that different drugs work through different mechanisms, and that the results of using multiple drugs will be synergistic to some extent. Because they have different dose-limiting adverse effects, they can be given together at full doses in chemotherapy regimens. The first successful combination chemotherapy was MOPP, introduced in 1963 for lymphomas. The term " induction regimen" refers to a chemotherapy regimen used for the initial treatment of a disease. A " maintenance regimen" refers to the ongoing use of chemotherapy to reduce the chances of ...
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Common Technical Document
The Common Technical Document (CTD) is a set of specifications for an application dossier for the registration of Medicines and designed to be used across Europe, Japan and the United States and beyond. Synopsis The CTD is an internationally agreed format for the preparation of applications regarding new drugs intended to be submitted to regional regulatory authorities in participating countries. It was developed by the European Medicines Agency (EMA, Europe), the Food and Drug Administration (FDA, US) and the Ministry of Health, Labour and Welfare (Japan) starting at the World Health Organization International Conference of Drug Regulatory Authorities (ICDRA) at Paris in 1989. The CTD is maintained by the International Council on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). After the United States, European Union and Japan, the CTD was adopted by several other countries including Canada and Switzerland. The Paper CTD is desti ...
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Connective Tissue Disease
A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds together, and protects organs. These tissues form a framework, or matrix, for the body, and are composed of two major structural protein molecules: collagen and elastin. There are many different types of collagen protein in each of the body's tissues. Elastin has the capability of stretching and returning to its original length—like a spring or rubber band. Elastin is the major component of ligaments (tissues that attach bone to bone) and skin. In patients with connective tissue disease, it is common for collagen and elastin to become injured by inflammation (ICT). Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissu ...
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Crash Test Dummies
Crash Test Dummies are a Canadian rock band from Winnipeg, Manitoba. The band is most identifiable through Brad Roberts (vocals, guitar) and his distinctive bass-baritone voice. The band members have fluctuated over the years, but its best known line-up consisted of Roberts, Ellen Reid (co-vocals, keyboards), Brad's brother Dan Roberts (bass guitar, backing vocals), Benjamin Darvill (harmonica, mandolin), and Mitch Dorge (drums, percussion). The band is best known internationally for their 1993 single " Mmm Mmm Mmm Mmm" and best known in Canada for the 1991 single " Superman's Song". History Beginnings: 1988–1991 The origin of Crash Test Dummies is tied to the history of two Winnipeg nightspots, the Spectrum Cabaret and the Blue Note Cafe, owned by Curtis Riddell. In 1986, Riddell joined with Brad Roberts to form the decidedly less-than-serious bar band Bad Brad Roberts and the St. James Rhythm Pigs. Over time, the band evolved into Crash Test Dummies, a name suggeste ...
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CTD (instrument)
''For information about the CTD-rosette equipment package as a whole, see: Rosette sampler'' A CTD or sonde is an oceanography instrument used to measure the electrical conductivity, temperature, and pressure of seawater (the D stands for "depth," which is closely related to pressure). Conductivity is used to determine salinity. The CTD may be incorporated into an array of Niskin bottles referred to as a carousel or rosette. The sampling bottles close at predefined depths, triggered either manually or by a computer, and the water samples may subsequently be analyzed further for biological and chemical parameters. The CTD may also be used for the calibration of sensors. Measured properties The instrument is a cluster of sensors which measure conductivity, temperature, and pressure. Sensors commonly scan at a rate of 24 Hz. Depth measurements are derived from measurement of hydrostatic pressure, and salinity is measured from electrical conductivity. Sensors are arrang ...
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Carboxy-Terminal Domain
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH). When the protein is translated from messenger RNA, it is created from N-terminus to C-terminus. The convention for writing peptide sequences is to put the C-terminal end on the right and write the sequence from N- to C-terminus. Chemistry Each amino acid has a carboxyl group and an amine group. Amino acids link to one another to form a chain by a dehydration reaction which joins the amine group of one amino acid to the carboxyl group of the next. Thus polypeptide chains have an end with an unbound carboxyl group, the C-terminus, and an end with an unbound amine group, the N-terminus. Proteins are naturally synthesized starting from the N-terminus and ending at the C-terminus. Function C-terminal retention signals While the N-terminus of a protein often conta ...
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Church–Turing–Deutsch Principle
In computer science and quantum physics, the Church–Turing–Deutsch principle (CTD principle) is a stronger, physical form of the Church–Turing thesis formulated by David Deutsch in 1985. The principle states that a universal computing device can simulate every physical process. History The principle was stated by Deutsch in 1985 with respect to finitary machines and processes. He observed that classical physics, which makes use of the concept of real numbers, cannot be simulated by a Turing machine, which can only represent computable reals. Deutsch proposed that quantum computers may actually obey the CTD principle, assuming that the laws of quantum physics can completely describe every physical process. An earlier version of this thesis for classical computers was stated by Alan Turing's friend and student Robin Gandy in 1980. See also * Bekenstein bound * Digital physics * Holographic principle * Quantum complexity theory Quantum complexity theory is the su ...
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Crash To Desktop
In computing, a crash, or system crash, occurs when a computer program such as a software application or an operating system stops functioning properly and exits. On some operating systems or individual applications, a crash reporting service will report the crash and any details relating to it (or give the user the option to do so), usually to the developer(s) of the application. If the program is a critical part of the operating system, the entire system may crash or hang, often resulting in a kernel panic or fatal system error. Most crashes are the result of a software bug. Typical causes include accessing invalid memory addresses, incorrect address values in the program counter, buffer overflow, overwriting a portion of the affected program code due to an earlier bug, executing invalid machine instructions (an illegal opcode), or triggering an unhandled exception. The original software bug that started this chain of events is typically considered to be the cause of th ...
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Continuous Threat Detection
Continuity or continuous may refer to: Mathematics * Continuity (mathematics), the opposing concept to discreteness; common examples include ** Continuous probability distribution or random variable in probability and statistics ** Continuous game, a generalization of games used in game theory ** Law of Continuity, a heuristic principle of Gottfried Leibniz * Continuous function, in particular: ** Continuity (topology), a generalization to functions between topological spaces ** Scott continuity, for functions between posets ** Continuity (set theory), for functions between ordinals ** Continuity (category theory), for functors ** Graph continuity, for payoff functions in game theory * Continuity theorem may refer to one of two results: ** Lévy's continuity theorem, on random variables ** Kolmogorov continuity theorem, on stochastic processes * In geometry: ** Parametric continuity, for parametrised curves ** Geometric continuity, a concept primarily applied to the conic sectio ...
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CBS Television Distribution
CBS Media Ventures, Inc. (formerly CBS Television Distribution, Inc. and CBS Paramount Domestic Television, Inc.) is an American television distribution company owned by CBS Studios, part of CBS Entertainment Group, a division of Paramount Global. It was formed from the merger of CBS Corporation's domestic television distribution arms CBS Paramount Domestic Television and King World Productions, including its home entertainment arm CBS Home Entertainment. The division, the main distribution arm of the parent company CBS Studios (formerly Desilu Productions, the first incarnation of Paramount Television, CBS Paramount Television and CBS Television Studios), the CBS and The CW television networks, and other Paramount Global television studios, such as the Paramount Media Networks division, was formed on September 26, 2006, by CBS Corporation and was headed by Roger King, the CEO of King World until his death in 2007. Background The company handles distribution rights ...
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