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CRACD-like Protein
CRACD-like protein. previously known as KIAA1211L is a protein that in humans is encoded by the ''CRACDL'' gene. It is highly expressed in the cerebral cortex of the brain. Furthermore, it is localized to the microtubules and the centrosomes and is subcellularly located in the Cell nucleus, nucleus. Finally, CRACDL is associated with certain mental disorders and various cancers. Gene ''CRACDL'' is a protein-coding gene. The table above presents the gene's alias, location, size and accession number. mRNA There are 11 splice isoforms of the ''CRACDL''. The validated isoform has 10 exons. Protein The table above presents the protein's alias, size, and accession number. The CRACD-L protein is proline rich and asparagine, isoleucine, phenylalanine, and tyrosine poor. Domains and motifs The CRACD-L protein has one domain called the DUF4592 motif and spans amino acids 131–239. This domain is highly conserved among the CRACDL Homology (biology), orthologs. The DUF4592 mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. It is the largest site of Neuron, neural integration in the central nervous system, and plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The six-layered neocortex makes up approximately 90% of the Cortex (anatomy), cortex, with the allocortex making up the remainder. The cortex is divided into left and right parts by the longitudinal fissure, which separates the two cerebral hemispheres that are joined beneath the cortex by the corpus callosum and other commissural fibers. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the neurocranium, cranium. Apart from minimising brain and cranial volume, gyrification, cortical folding is crucial for the Neural circuit, brain circuitry ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
