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COVID-19 Case-Cluster-Study
The COVID-19 Case-Cluster-Study – colloquially, Heinsberg study, also known as Heinsbergprotokoll and HEINSBERG PROTOKOLL. – is a study about the COVID-19 pandemic in Gangelt. The study was commissioned and is co-financed by the government of North Rhine-Westphalia and is led by Hendrik Streeck. In the public sphere, the marketing agency StoryMachine presented its results on Facebook and Twitter. Private enterprises also co-financed the study. The results of the study garnered cross-national media attention. The study aimed to determine lethality of and Immunity (medical), immunity to Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2; it also estimated the number of unrecorded cases. Despite the fact that sample size does not determine the representativeness of a study, principal investigator Streeck claims, they examined more persons than recommended by the World Health Organization, the study would "thus be statistically absolutely representative". Critic ...
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Hendrik Streeck
Hendrik Streeck (born 7 August 1977 in Göttingen) is a German researcher of human immunodeficiency virus, epidemiologist and clinical trialist. He is professor of virology and the director of the Institute of Virology and HIV Research at the University of Bonn, University Bonn. Early life and education Streeck studied medicine at the Charité, Charite University, Berlin. After his graduation he started to work as a postdoctoral fellow at the Ragon Institute of Massachusetts General Hospital, the Massachusetts Institute of Technology, and Harvard Medical School and obtained his PhD from the University of Bonn, and part-time at the Partners AIDS Research Center, Massachusetts General Hospital and Harvard Medical School. Career In 2009 Streeck was promoted to Instructor in Medicine and in 2011 to Assistant Professor at Harvard Medical School. In September 2012 he was recruited to the United States Military HIV Research Program, Bethesda, where he became the Chief of the Cell ...
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Immunity (medical)
In biology, immunity is the state of being insusceptible or resistant to a noxious agent or process, especially a pathogen or infectious disease. Immunity may occur naturally or be produced by prior exposure or immunization. Innate and adaptive The immune system has Innate immune system, innate and Adaptive immune system, adaptive components. Innate immunity is present in all metazoans, immune responses: inflammation, inflammatory responses and phagocytosis. The adaptive component, on the other hand, involves more advanced lymphocyte, lymphatic cells that can distinguish between specific "non-self" substances in the presence of "self". The reaction to foreign substances is etymologically described as inflammation while the non-reaction to self substances is described as immunity. The two components of the immune system create a dynamic biological environment where "health" can be seen as a physical state where the self is immunologically spared, and what is foreign is inflammat ...
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COVID-19 Pandemic In Germany
The COVID-19 pandemic in Germany has resulted in confirmed cases of COVID-19 and deaths. On 27 January 2020, the first case in Germany was confirmed near Munich, Bavaria. By mid February, the arising cluster of cases had been fully contained. On 25 and 26 February, multiple cases related to the COVID-19 pandemic in Italy, Italian outbreak were detected in Baden-Württemberg. A carnival event on 15 February in Heinsberg (district), Heinsberg, North Rhine-Westphalia, was attended by a man identified as positive on 25 February; in the outbreak which subsequently developed from infected participants, authorities were mostly no longer able to trace the likely chains of infections. On 9 March, the first two deaths in Germany were reported from Essen and Heinsberg. New clusters were introduced in other regions via Heinsberg as well as via people arriving from China, Iran and Italy, from where non-Germans could arrive by plane until German government response to the COV ...
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Nature Communications
''Nature Communications'' is a peer-reviewed, open access, scientific journal published by Nature Portfolio since 2010. It is a multidisciplinary journal that covers the natural sciences, including physics, chemistry, earth sciences, medicine, and biology. The journal has editorial offices in London, Berlin, New York City, and Shanghai. The founding editor-in-chief was Lesley Anson, followed by Joerg Heber, Magdalena Skipper, and Elisa De Ranieri. the editors are Nathalie Le Bot for health and clinical sciences, Stephane Larochelle for biological sciences, Enda Bergin for chemistry and biotechnology, and Prabhjot Saini for physics and earth sciences. Starting October 2014, the journal only accepted submissions from authors willing to pay an article processing charge. Until the end of 2015, part of the published submissions were only available to subscribers. In January 2016, all content became freely accessible. Starting from 2017, the journal offers a deposition ser ...
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World Health Organization
The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Geneva, Switzerland, and has 6 regional offices and 150 field offices worldwide. Only sovereign states are eligible to join, and it is the largest intergovernmental health organization at the international level. The WHO's purpose is to achieve the highest possible level of health for all the world's people, defining health as "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity." The main functions of the World Health Organization include promoting the control of epidemic and endemic diseases; providing and improving the teaching and training in public health, the medical treatment of disease, and related matters; and promoting the establishment of international standards for biologic ...
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Representativeness
The representativeness heuristic is used when making judgments about the probability of an event being representational in character and essence of a known prototypical event. It is one of a group of heuristics (simple rules governing judgment or decision-making) proposed by psychologists Amos Tversky and Daniel Kahneman in the early 1970s as "the degree to which n event(i) is similar in essential characteristics to its parent population, and (ii) reflects the salient features of the process by which it is generated". The representativeness heuristic works by comparing an event to a prototype or stereotype that we already have in mind. For example, if we see a person who is dressed in eccentric clothes and reading a poetry book, we might be more likely to think that they are a poet than an accountant. This is because the person's appearance and behavior are more representative of the stereotype of a poet than an accountant. The representativeness heuristic can be a useful shortcu ...
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Sample Size
Sample size determination or estimation is the act of choosing the number of observations or replicates to include in a statistical sample. The sample size is an important feature of any empirical study in which the goal is to make inferences about a population from a sample. In practice, the sample size used in a study is usually determined based on the cost, time, or convenience of collecting the data, and the need for it to offer sufficient statistical power. In complex studies, different sample sizes may be allocated, such as in stratified surveys or experimental designs with multiple treatment groups. In a census, data is sought for an entire population, hence the intended sample size is equal to the population. In experimental design, where a study may be divided into different treatment groups, there may be different sample sizes for each group. Sample sizes may be chosen in several ways: *using experience – small samples, though sometimes unavoidable, can result in wid ...
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Severe Acute Respiratory Syndrome Coronavirus 2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19, the respiratory illness responsible for the COVID-19 pandemic. The virus previously had the Novel coronavirus, provisional name 2019 novel coronavirus (2019-nCoV), and has also been called human coronavirus 2019 (HCoV-19 or hCoV-19). First identified in the city of Wuhan, Hubei, China, the World Health Organization designated the outbreak a public health emergency of international concern from January 30, 2020, to May 5, 2023. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus that is Contagious disease, contagious in humans. SARS‑CoV‑2 is a strain of the species ''Betacoronavirus pandemicum'' (SARSr-CoV), as is SARS-CoV-1, the virus that caused the 2002–2004 SARS outbreak. There are animal-borne coronavirus strains more closely related to SARS-CoV-2, the most closely known relative being the BANAL-52 bat coronavirus. SARS-CoV-2 is of Zoonosis, z ...
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Lethality
Lethality (also called deadliness or perniciousness) is how capable something is of causing death. Most often it is used when referring to diseases, chemical weapons, biological weapons, or their toxic chemical components. The use of this term denotes the ability of these weapons to kill, but also the possibility that they may not kill. Reasons for the lethality of a weapon to be inconsistent, or expressed by percentage, can be as varied as minimized exposure to the weapon, previous exposure to the weapon minimizing susceptibility, degradation of the weapon over time and/or distance, and incorrect deployment of a multi-component weapon. This term can also refer to the after-effects of weapon use, such as nuclear fallout, which has highest lethality nearest the deployment site, and in proportion to the subject's size and nature; e.g. a child or small animal. Lethality can also refer to the after-effects of a major chemical or oil/gas process loss of containment, causing fire, ex ...
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COVID-19 Pandemic
The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December 2019. Soon after, it spread to other areas of Asia, and COVID-19 pandemic by country and territory, then worldwide in early 2020. The World Health Organization (WHO) declared the outbreak a public health emergency of international concern (PHEIC) on 30 January 2020, and assessed the outbreak as having become a pandemic on 11 March. COVID-19 symptoms range from asymptomatic to deadly, but most commonly include fever, sore throat, nocturnal cough, and fatigue. Transmission of COVID-19, Transmission of the virus is often airborne transmission, through airborne particles. Mutations have variants of SARS-CoV-2, produced many strains (variants) with varying degrees of infectivity and virulence. COVID-19 vaccines were developed rapidly and deplo ...
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Twitter
Twitter, officially known as X since 2023, is an American microblogging and social networking service. It is one of the world's largest social media platforms and one of the most-visited websites. Users can share short text messages, images, and videos in Microblogging, short posts commonly known as "Tweet (social media), tweets" (officially "posts") and Like button, like other users' content. The platform also includes direct message, direct messaging, video and audio calling, bookmarks, lists, communities, a chatbot (Grok (chatbot), Grok), job search, and Spaces, a social audio feature. Users can vote on context added by approved users using the Community Notes feature. Twitter was created in March 2006 by Jack Dorsey, Noah Glass, Biz Stone, and Evan Williams (Internet entrepreneur), Evan Williams, and was launched in July of that year. Twitter grew quickly; by 2012 more than 100 million users produced 340 million daily tweets. Twitter, Inc., was based in San Francisco, C ...
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Facebook
Facebook is a social media and social networking service owned by the American technology conglomerate Meta Platforms, Meta. Created in 2004 by Mark Zuckerberg with four other Harvard College students and roommates, Eduardo Saverin, Andrew McCollum, Dustin Moskovitz, and Chris Hughes, its name derives from the face book directories often given to American university students. Membership was initially limited to Harvard students, gradually expanding to other North American universities. Since 2006, Facebook allows everyone to register from 13 years old, except in the case of a handful of nations, where the age requirement is 14 years. , Facebook claimed almost 3.07 billion monthly active users worldwide. , Facebook ranked as the List of most-visited websites, third-most-visited website in the world, with 23% of its traffic coming from the United States. It was the most downloaded mobile app of the 2010s. Facebook can be accessed from devices with Internet connectivit ...
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