C5orf34
C5orf34 (chromosome 5 open reading frame 34) is a protein that in humans is encoded by the ''C5orf34'' gene (5p12). C5orf34 is conserved in mammals, birds and reptiles with the most distant ancestor being the Burmese python, ''Python bivittatus''. The C5orf34 protein contains two mammalian conserved domains: DUF 4520 and DUF 4524. The protein is also predicted to have a polo-box domain (PBD) of polo-like kinase 4 (plk4), which has predicted conservation in distant orthologs from the clade Aves. Gene ''C5orf34'' is located on the negative DNA strand of the short arm of chromosome 6 at locus 12. The gene is 28,744 base pairs long and spans from base pair 43,486,701 to base pair 43,515,445. The gene produces a single transcript of 2,540 base pairs long and encodes for 638 amino acids. Gene neighborhood The gene ''PAIP1'' is found on the negative strand just downstream of ''C5orf34'' and is a member of the polyadenylate-binding family. ''PAIP1'' extends from base pairs 43,526 ...
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