Ansamycins
Ansamycins is a family of bacterial secondary metabolites that show antimicrobial activity against many Gram-positive and some Gram-negative bacteria, and includes various compounds, including streptovaricins and rifamycins. In addition, these compounds demonstrate antiviral activity towards bacteriophages and poxviruses. They are somewhat similar in structure to macrolide antibiotics, but because they have a lactam instead of a lactone, they do not belong in the class of macrolides. __TOC__ Structure They are named ansamycins (from the Latin ansa, ''handle'') because of their unique structure, which consists of an aromatic moiety bridged by an aliphatic chain. The main difference between various derivatives of ansamycins is the aromatic moiety, which can be a naphthalene ring or a naphthoquinone ring as in rifamycin and the naphthomycins. Another variation consists of benzene or a benzoquinone ring system as in geldanamycin or ansamitocin. Ansamycins were first discovered ...
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Streptovaricins
Streptovaricins are a group of structurally related macrolide antibiotics. They belong to the larger class of antibiotics known as ansamycins. References

Macrolide antibiotics Ansamycins {{antibiotic-stub ...
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