Bruceanol D

	Bruceanol D Bruceanol D is a cytotoxic quassinoid isolated from ''Brucea antidysenterica'' with potential antitumor and antileukemic properties. See also * Bruceanol Bruceanol A-H Bruceanols are quassinoid Quassinoids are degraded triterpene lactones (similar to limonoids) of the Simaroubaceae plant family grouped into C-18, C-19, C-20, C-22 and C-25 types. The prototypical member of the group, quassin, wa ... References Quassinoids Heterocyclic compounds with 5 rings Methyl esters {{organic-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Quassinoid Quassinoids are degraded triterpene lactones (similar to limonoids) of the Simaroubaceae plant family grouped into C-18, C-19, C-20, C-22 and C-25 types. The prototypical member of the group, quassin, was first described in the 19th century from plants of the genus '' Quassia'' from which it gets its name. It was isolated in 1937 and its structure elucidated in 1961. They are a biologically potent class of natural products, possessing antimalarial, antifeedant, insecticidal, anti-inflammatory, and anticancer properties. The quassinoid bruceantin reached two separate phase II clinical trials in 1982 and 1983. Other quassinoids include: * Bruceanols * Bruceolide * Eurycomanone * Gutolactone Gutolactone is a chemical compound extracted from '' Simaba guianensis'' and it has displayed antimalarial properties ''in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biol ... * Isobrucein A * Neoquassin * Nigaki ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Brucea Antidysenterica ''Brucea'' is a genus of plant in the family Simaroubaceae. It is named for the Scottish scholar and explorer James Bruce. It contains the following species (this list may be incomplete): * '' Brucea antidysenterica'' * '' Brucea bruceadelpha'' * '' Brucea erythraeae'' * '' Brucea guineensis'' * ''Brucea javanica'' * '' Brucea macrocarpa'' * ''Brucea mollis ''Brucea'' is a genus of plant in the family Simaroubaceae. It is named for the Scottish scholar and explorer James Bruce. It contains the following species (this list may be incomplete): * '' Brucea antidysenterica'' * '' Brucea bruceadelpha' ...'' * '' Brucea tenuifolia'' * '' Brucea tonkinensis'' * '' Brucea trichotoma'' References Sapindales genera Taxa named by John Frederick Miller Taxonomy articles created by Polbot {{sapindales-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Bruceanol Bruceanol A-H Bruceanols are quassinoids isolated from ''Brucea antidysenterica''. Bruceanols * Bruceanol A * Bruceanol B * Bruceanol C * Bruceanol D * Bruceanol E * Bruceanol F * Bruceanol G * Bruceanol H Bruceanol H is a cytotoxic quassinoid isolated from ''Brucea antidysenterica'' with potential antitumor and antileukemic properties. See also * Bruceanol Bruceanol A-H Bruceanols are quassinoid Quassinoids are degraded triterpene lactones (sim ... References Quassinoids {{organic-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Quassinoids Quassinoids are degraded triterpene lactones (similar to limonoids) of the Simaroubaceae The Simaroubaceae are a small, mostly tropical, family in the order Sapindales. In recent decades, it has been subject to much taxonomic debate, with several small families being split off. A molecular phylogeny of the family was published in 200 ... plant family grouped into C-18, C-19, C-20, C-22 and C-25 types. The prototypical member of the group, quassin, was first described in the 19th century from plants of the genus '' Quassia'' from which it gets its name. It was isolated in 1937 and its structure elucidated in 1961. They are a biologically potent class of natural products, possessing antimalarial, antifeedant, insecticidal, anti-inflammatory, and anticancer properties. The quassinoid bruceantin reached two separate phase II clinical trials in 1982 and 1983. Other quassinoids include: * Bruceanols * Bruceolide * Eurycomanone * Gutolactone * Isobrucein A * Neoquassin * Niga ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Heterocyclic Compounds With 5 Rings A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different chemical element, elements as members of its ring(s). Heterocyclic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and applications of these heterocycles. Examples of heterocyclic compounds include all of the nucleic acids, the majority of drugs, most biomass (cellulose and related materials), and many natural and synthetic dyes. More than half of known compounds are heterocycles. 59% of US FDA-approved drugs contain nitrogen heterocycles. Classification The study of heterocyclic chemistry focuses especially on unsaturated derivatives, and the preponderance of work and applications involves unstrained 5- and 6-membered rings. Included are pyridine, thiophene, pyrrole, and furan. Another large class of heterocycles refers to those fused to benzene rings. For example, the fused benzene derivatives of pyridine, thiophene, pyrrole, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]