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Bruce H. Lipshutz
Bruce H. Lipshutz (born 1951) is an American chemist. He is a professor at the University of California, Santa Barbara. Biography Lipshutz received his undergraduate degree in chemistry from Binghamton University in 1973. His graduate work was supervised by Harry H. Wasserman at Yale. After a PhD degree in 1977, he spent two years at Harvard as a post-doctoral researcher in the group of Nobel Laureate E. J. Corey. Soon after, he accepted a position of Assistant Professor at UCSB rising to the ranks of Professor in 1987. He has received the Alfred P. Sloan Foundation Fellowship and the Camille & Henry Dreyfus Teacher-Scholar Award. In 2011 he was awarded Presidential Green Chemistry Award. He is Co-founder of Zymes LLC. Contributions Reagents *Aqueous Micellar Catalysis using TPGS-750-M and Nok. *Sustainable Palladium catalysis. * 2-(Trimethylsilyl)ethoxymethyl chloride: hydroxyl protecting group, selectively cleaved with fluoride ion under mild conditions. Di-(4-chlorobenzyl)a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, Santa Barbara
The University of California, Santa Barbara (UC Santa Barbara or UCSB) is a Public university, public Land-grant university, land-grant research university in Santa Barbara County, California, United States. Tracing its roots back to 1891 as an independent teachers college, UCSB joined the University of California system in 1944. It is the third-oldest undergraduate campus in the system, after University of California, Berkeley, UC Berkeley and University of California, Los Angeles, UCLA. UCSB's campus sits on the oceanfront site of a converted WWII-era United States Marine Corps, Marine Corps air station. UCSB is organized into three undergraduate colleges (UCSB College of Letters and Science, Letters and Science, UCSB College of Engineering, Engineering, College of Creative Studies, Creative Studies) and two graduate schools (Gevirtz Graduate School of Education, Education and Bren School of Environmental Science & Management, Environmental Science & Management), offering more ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Binghamton University
The State University of New York at Binghamton (Binghamton University or SUNY Binghamton) is a public university, public research university in Binghamton metropolitan area, Greater Binghamton, New York, United States. It is one of the four university centers in the State University of New York (SUNY) system. Since its establishment in 1946, the school has evolved from a small Liberal arts colleges in the United States, liberal arts college to a large research university. It is Carnegie Classification of Institutions of Higher Education, classified among List of research universities in the United States, R1: Doctoral Universities – Very high research activity. Binghamton's athletic teams are the Binghamton Bearcats, Bearcats and they compete in NCAA Division I, Division I of the National Collegiate Athletic Association (NCAA). The Bearcats are members of the America East Conference. History Establishment Binghamton University was established in 1946 in Endicott, New York, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harry H
Harry may refer to: Television * ''Harry'' (American TV series), 1987 comedy series starring Alan Arkin * ''Harry'' (British TV series), 1993 BBC drama that ran for two seasons * ''Harry'' (New Zealand TV series), 2013 crime drama starring Oscar Kightley * ''Harry'' (talk show), 2016 American daytime talk show hosted by Harry Connick Jr. People and fictional characters *Harry (given name), a list of people and fictional characters with the given name, including **Prince Harry, Duke of Sussex (born 1984) *Harry (surname), a list of people with the surname Other uses *"Harry", the tunnel used in the Stalag Luft III escape ("The Great Escape") of World War II * ''Harry'' (album), a 1969 album by Harry Nilsson *Harry (derogatory term) Harry is a Norwegian derogatory term used in slang, derived from the English name Harry. The best English translation may be "cheesy" or "tacky". '' Norsk ordbok'' defines "harry" as "tasteless, vulgar". The term "harry" was first used by upper ... ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale
Yale University is a private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the third-oldest institution of higher education in the United States, and one of the nine colonial colleges chartered before the American Revolution. Yale was established as the Collegiate School in 1701 by Congregationalist clergy of the Connecticut Colony. Originally restricted to instructing ministers in theology and sacred languages, the school's curriculum expanded, incorporating humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew rapidly after 1890 due to the expansion of the physical campus and its scientific research programs. Yale is organized into fifteen constituent schools, including the original under ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard
Harvard University is a private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of colonial-era Massachusetts Bay Colony. While never formally affiliated with any denomination, Harvard trained Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston elite. Following the American Civil War, under Harvard president Charles William Eliot's long tenure from 1869 to 1909, Harvard developed multiple professional schools, which transfo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UCSB
The University of California, Santa Barbara (UC Santa Barbara or UCSB) is a public land-grant research university in Santa Barbara County, California, United States. Tracing its roots back to 1891 as an independent teachers college, UCSB joined the University of California system in 1944. It is the third-oldest undergraduate campus in the system, after UC Berkeley and UCLA. UCSB's campus sits on the oceanfront site of a converted WWII-era Marine Corps air station. UCSB is organized into three undergraduate colleges ( Letters and Science, Engineering, Creative Studies) and two graduate schools (Education and Environmental Science & Management), offering more than 200 degrees and programs. It is classified among "R1: Doctoral Universities – Very high research activity" and is regarded as a Public Ivy. The university has 12 national research centers and institutes, including the Kavli Institute for Theoretical Physics and NSF Quantum Foundry. According to the National Scie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alfred P
Alfred may refer to: Arts and entertainment *'' Alfred J. Kwak'', Dutch-German-Japanese anime television series * ''Alfred'' (Arne opera), a 1740 masque by Thomas Arne * ''Alfred'' (Dvořák), an 1870 opera by Antonín Dvořák *"Alfred (Interlude)" and "Alfred (Outro)", songs by Eminem from the 2020 album '' Music to Be Murdered By'' Business and organisations * Alfred, a radio station in Shaftesbury, England * Alfred Music, an American music publisher * Alfred University, New York, U.S. * The Alfred Hospital, a hospital in Melbourne, Australia People * Alfred (name) includes a list of people and fictional characters called Alfred * Alfred the Great (848/49 – 899), or Alfred I, a king of the West Saxons and of the Anglo-Saxons Places Antarctica * Mount Alfred (Antarctica) Australia * Alfredtown, New South Wales * County of Alfred, South Australia Canada * Alfred and Plantagenet, Ontario ** Alfred, Ontario, a community in Alfred and Plantagenet * Alfred Island, Nunavu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2-(Trimethylsilyl)ethoxymethyl Chloride
2-(Trimethylsilyl)ethoxymethyl chloride (SEM-Cl) is an organochlorine compound with the formula C6H15ClOSi, which was developed by Bruce H. Lipshutz during his work on the synthesis of ''N''-methylmaysenine. It is used to protect hydroxyl groups, which can be cleaved with fluoride in organic solvents selectively under mild conditions. Typically tetrabutylammonium fluoride and caesium fluoride can be used as deprotection reagents. Alternatives such as magnesium bromide, lithium tetrafluoroborate and boron trifluoride Boron trifluoride is the inorganic compound with the formula . This pungent, colourless, and toxic gas forms white fumes in moist air. It is a useful Lewis acid and a versatile building block for other boron compounds. Structure and bonding The g ... etherate were also developed to deprotect SEM group. References Further reading * {{DEFAULTSORT:Trimethylsilyl)ethoxymethyl chloride, 2-( Chloromethyl compounds Trimethylsilyl compounds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mitsunobu Reaction
The Mitsunobu reaction is an organic reaction that converts an alcohol into a variety of functional groups, such as an ester, using triphenylphosphine and an azodicarboxylate such as diethyl azodicarboxylate (DEAD) or diisopropyl azodicarboxylate (DIAD). Although DEAD and DIAD are most commonly used, there are a variety of other azodicarboxylates available which facilitate an easier workup and/or purification and in some cases, facilitate the use of more basic nucleophiles. It was discovered by Oyo Mitsunobu (1934–2003). In a typical protocol, one dissolves the alcohol, the carboxylic acid, and triphenylphosphine in tetrahydrofuran or other suitable solvent (e.g. diethyl ether), cool to 0 °C using an ice-bath, slowly add the DEAD dissolved in THF, then stir at room temperature for several hours. The alcohol reacts with the phosphine to create a good leaving group then undergoes an inversion of stereochemistry in classic SN2 fashion as the nucleophile displaces it. A c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coenzyme Q10
Coenzyme Q10 (CoQ10 ), also known as ubiquinone, is a naturally occurring biochemical cofactor (coenzyme) and an antioxidant produced by the human body. It can also be obtained from dietary sources, such as meat, fish, seed oils, vegetables, and dietary supplements. CoQ10 is found in many organisms, including animals and bacteria. CoQ10 plays a role in mitochondrial oxidative phosphorylation, aiding in the production of adenosine triphosphate (ATP), which is involved in energy transfer within cells. The structure of CoQ10 consists of a benzoquinone moiety and an isoprenoid side chain, with the "10" referring to the number of isoprenyl chemical subunits in its tail. Although a ubiquitous molecule in human tissues, CoQ10 is not a dietary nutrient and does not have a recommended intake level, and its use as a supplement is not approved in the United States for any health or anti-disease effect. Biological functions CoQ10 is a component of the mitochondrial electron trans ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1951 Births
Events January * January 4 – Korean War: Third Battle of Seoul – Chinese and North Korean forces capture Seoul for the second time (having lost the Second Battle of Seoul in September 1950). * January 9 – The Government of the United Kingdom announces abandonment of the Tanganyika groundnut scheme for the cultivation of peanuts in the Tanganyika Territory, with the writing off of £36.5M debt. * January 11 – In the U.S., a top secret report is delivered to U.S. President Truman by his National Security Resources Board, urging Truman to expand the Korean War by launching "a global offensive against communism" with sustained bombing of Red China and diplomatic moves to establish "moral justification" for a U.S. nuclear attack on the Soviet Union. The report will not not be declassified until 1978. * January 15 – In a criminal court in West Germany, Ilse Koch, The "Witch of Buchenwald", wife of the commandant of the Buchenwald concentration camp, is sentenced to li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
