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Bone Spavin
Bone spavin is a bony growth within the lower hock joint of horses or cattle. It is caused by osteoarthritis, and the degree of lameness that results can be serious enough to end a horse's competitive career. Description Bone spavin is osteoarthritis, or the final phase of degenerative joint disease (DJD), in the lower three hock joints. It usually affects the two lowest joints of the hock (the tarsometatarsal and the distal intertarsal joints), with the third joint, the proximal intertarsal, being the least likely to develop bone spavin. This condition has various types: jack spavin when there is significant bony enlargement over the tarsal bones, and high spavin when the pathology occurs higher in the joint than is typical. Conversely, occult spavin does not produce any significant exostoses on the small tarsals, whilst bog spavin and blood spavin do not involve bony changes. Causes Cartilage compression Excessive compression can cause, over time, the cartilage between the u ...
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Hock (zoology)
The hock, tarsus or uncommonly gambrel, is the region formed by the tarsal bones connecting the tibia and metatarsus of a digitigrade or unguligrade quadrupedal mammal, such as a horse, cat, or dog. This joint may include articulations between tarsal bones and the fibula in some species (such as cats), while in others the fibula has been greatly reduced and is only found as a vestigial remnant fused to the distal portion of the tibia (as in horses). It is the anatomical homologue of the ankle of the human foot. While homologous joints occur in other tetrapods, the term is generally restricted to mammals, particularly long-legged domesticated species. Horse The terms ''tarsus'' and ''hock'' refer to the region between the gaskin (crus) and cannon regions (metatarsus), which includes the bones, joints, and soft tissues of the area. The hock is especially important in equine anatomy, due to the great strain it receives when the horse is worked. Jumping, quick turns or s ...
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Flexion Test
A flexion test is a preliminary veterinary procedure performed on a horse, generally during a prepurchase or a lameness exam. The purpose is to accentuate any pain that may be associated with a joint or soft-tissue structure, allowing the practitioner to localize a lameness to a specific area, or to alert a practitioner to the presence of sub-clinical disease that may be present during a pre-purchase exam. Performing a flexion test The animal's leg is held in a flexed position for 30 seconds to up to 3 minutes (although most veterinarians do not go longer than a minute),Baxter, Gary (2011). Manual of Equine Lameness. Wiley-Blackwell. . and then the horse is immediately trotted off and its gait is analyzed for abnormalities and unevenness.Ramey, DW. Prospective Evaluation of Forelimb Flexion Tests in Practice: Clinical Response, Radiographic Correlations, and Predictive Value for Future Lameness. Proc. AAEP, 1997, Vol. 43; 116-119. Flexions stretch the joint capsule, increase intra- ...
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Hyaluronan
Hyaluronic acid (; abbreviated HA; conjugate acid, conjugate base hyaluronate), also called hyaluronan, is an anion#Anions and cations, anionic, Sulfation, nonsulfated glycosaminoglycan distributed widely throughout connective tissue, connective, epithelial tissue, epithelial, and neural tissues. It is unique among glycosaminoglycans as it is non-sulfated, forms in the plasma membrane instead of the Golgi apparatus, and can be very large: human Synovial fluid, synovial HA averages about per molecule, or about 20,000 disaccharide monomers, while other sources mention . Medically, hyaluronic acid is used to treat osteoarthritis of the knee and dry eye, for wound repair, and as a cosmetic filler. The average 70 kg (150 lb) person has roughly 15 grams of hyaluronan in the body, one third of which is turned over (i.e., degraded and synthesized) per day. As one of the chief components of the extracellular matrix, it contributes significantly to cell proliferation and ...
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Autologous Conditioned Serum
Autologous conditioned serum, also known as Orthokine and Regenokine, is an experimental procedure in which a person's own blood is extracted, manipulated, and then reintroduced with claimed benefit in osteoarthritis. There is limited evidence on safety and effectiveness as of 2017. It is not included in medical guidelines as of 2017. It is a type of autologous blood therapy. Medical use There is limited evidence on safety and effectiveness as of 2017. There is tentative evidence in osteoarthritis. Its use has not been recommended or considered by the Osteoarthritis Research Society International. Process The process removes about of blood from a patient's arm, which is then incubated at a slightly raised temperature. The liquid is then placed in a centrifuge until its constituent parts are separated. That serum is injected into the patient's affected area. History Autologous conditioned serum is a patented method developed by molecular biologist Julio Reinecke and Peter ...
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Platelet-rich Plasma
Platelet-rich plasma (PRP), also known as autologous conditioned plasma, is a concentrate of plasma protein derived from whole blood, centrifuged to remove red blood cells but retaining platelets. Though promoted for treating various medical conditions, evidence of its benefits was mixed as of 2020, showing effectiveness in certain conditions and ineffectiveness in others. As a concentrated source of blood plasma and autologous conditioned plasma, PRP contains multiple growth factors and other cytokines that can stimulate the healing of soft tissues and joints. Indications for its use include sports medicine and orthopaedics (such as acute muscle strains, tendinopathy, tendinosis, muscle-fascial injuries, and osteoarthritis) dermatology (for androgenic alopecia, wound healing, and skin rejuvenation), and even proctology (for fistula en ano). Various preparation protocols exist, with the underlying principle of concentrating platelets to 3–5 times physiological levels, then ...
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Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. Some common naturally occurring steroid hormones are cortisol (), corticosterone (), cortisone () and aldosterone () (cortisone and aldosterone are isomers). The main corticosteroids produced by the adrenal cortex are cortisol and aldosterone. The etymology of the '' cortico-'' part of the name refers to the adrenal cortex, which makes these steroid hormones. Thus a corticosteroid is a "cortex steroid". Classes * Glucocorticoids such as cortisol affect carbohydrate, fat, and protein metabolism, and have anti ...
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Horse Colic
Colic in horses is defined as abdominal pain, but it is a clinical symptom rather than a diagnosis. The term colic can encompass all forms of gastrointestinal conditions which cause pain as well as other causes of abdominal pain not involving the gastrointestinal tract. What makes it tricky is that different causes can manifest with similar signs of distress in the animal. Recognizing and understanding these signs is pivotal, as timely action can spell the difference between a brief moment of discomfort and a life-threatening situation. The most common forms of colic are gastrointestinal in nature and are most often related to colonic disturbance. There are a variety of different causes of colic, some of which can prove fatal without surgical intervention. Colic surgery is usually an expensive procedure as it is major abdominal surgery, often with intensive aftercare. Among domesticated horses, colic is the leading cause of premature death. The incidence of colic in the general ...
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Equine Gastric Ulcer Syndrome
Equine gastric ulcer syndrome (EGUS) is a common cause of colic and decreased performance in horses. Horses form ulcers in the mucosa of the stomach, leading to pain, decreased appetite, weight loss, and behavioral changes. Treatment generally involves reducing acid production of the stomach and dietary management. Unlike some animals, however, stomach rupture is rare, and the main goal of treating is to reduce pain and improve performance of animals used for showing or racing. Pathophysiology The digestive system of the horse evolved for its grazing lifestyle, where it would almost constantly eat small amounts of roughage throughout the day. Unlike carnivores, who produce stomach acid during meals, horses constantly secrete acid to help digest this source of grass, leading up to 9 gallons produced per day. Unchecked, the stomach acid can lower the pH to levels that will damage the gastric mucosa, leading to ulcers. The stomach is divided into two main sections: a squamous region ...
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Non-steroidal Anti-inflammatory Drug
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of gastrointestinal ulcers and bleeds, heart attack, and kidney disease. The term ''non-steroidal'', common from around 1960, distinguishes these drugs from corticosteroids, another class of anti-inflammatory drugs, which during the 1950s had acquired a bad reputation due to overuse and side-effect problems after their introduction in 1948. NSAIDs work by inhibiting the activity of cyclooxygenase enzymes (the COX-1 and COX-2 isoenzymes). In cells, these enzymes are involved in the synthesis of key biological mediators, namely prostaglandins, which are involved in inflammation, and thromboxanes, which are involved in blood clotting. There are two general types of NSAIDs available: non-selec ...
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Scintigraphy
Scintigraphy (from Latin ''scintilla'', "spark"), also known as a gamma scan, is a diagnostic test in nuclear medicine, where radioisotopes attached to drugs that travel to a specific organ or tissue (radiopharmaceuticals) are taken internally and the emitted gamma ray, gamma radiation is captured by gamma cameras, which are external detectors that form two-dimensional images in a process similar to the capture of radiography, x-ray images. In contrast, Single photon emission computed tomography, SPECT and positron emission tomography (PET) form 3-dimensional images and are therefore classified as separate techniques from scintigraphy, although they also use gamma cameras to detect internal radiation. Scintigraphy is unlike a diagnostic X-ray where external radiation is passed through the body to form an image. Process Scintillography is an Molecular imaging, imaging method of nuclear events provoked by collisions or charged current interactions among nuclear particles or ioniz ...
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Suspensory Ligament
A suspensory ligament is a ligament that supports a body part, especially an organ. Types include: * Suspensory ligament of axilla, also known as Gerdy's ligament * Cooper's ligaments, also known as the suspensory ligaments of Cooper or Suspensory ligaments of breast * Suspensory ligament of clitoris * Suspensory ligament of duodenum, also known as the ligament of Treitz * Suspensory ligament of eyeball, also known as Lockwood's ligament * Suspensory ligament of lens, also known as the zonule of Zinn or zonular fibre * Suspensory ligament of ovary * Suspensory ligament of penis * Suspensory ligament of thyroid gland, also known as Berry's ligament * Part of the suspensory apparatus of the leg of a horse The horse (''Equus ferus caballus'') is a domesticated, one-toed, hoofed mammal. It belongs to the taxonomic family Equidae and is one of two extant subspecies of ''Equus ferus''. The horse has evolved over the past 45 to 55 mi .... When the leg is supp ...
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