Bogusław Bobrański
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Bogusław Bobrański
Bogusław Bobrański (; 10 May 1904 in Nowy Sącz - 1991) was a Polish chemist. He was the rector of Wrocław Medical University from 1957 - 1962. Biography Graduating in Chemistry from the Lviv Polytechnic, Bobrański received his engineering diploma in 1926. He worked in the Department of Organic Chemistry of his university under the supervision of Prof. Edward Sucharda. Bobrański obtained his doctorate in 1929 and habilitation in 1932. He became head of the Department of Organic and Pharmaceutical Chemistry at the Pharmacy Department of the Jan Kazimierz University in Lviv . During the war, he briefly worked as a professor at the National Institute of Medicine in Lviv, managing the Department of Pharmaceutical Chemistry. After the forced eviction from Lwów in 1946, he found himself in Wrocław. He worked at the Pharmaceutical Department at the Faculty of Medicine at the local Polytechnic and University. He became the head of the Department of Organic and Pharmaceutical Ch ...
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Psychoactive Drug
A psychoactive drug, psychopharmaceutical, psychoactive agent or psychotropic drug is a chemical substance, that changes functions of the nervous system, and results in alterations in perception, mood, consciousness, cognition or behavior. These substances may be used medically, recreationally or spiritually to a. Purposefully improve one’s perceived performance b. Alter one's consciousness (such as with entheogens for ritual, spiritual or shamanic purposes) or c. For research. Some categories of psychoactive drugs - which are believed, by some, to have therapeutic value - may be prescribed by some physicians and other healthcare practitioners. Examples of medication categories that may contain potentially beneficial psychoactive drugs include, but are not limited to: # Anesthetics # Analgesics # Anticonvulsants # Anti-Parkinson’s medications # Medications used to treat Neuropsychiatric Disorders a. Antidepressants b. Anxiolytics c. Antipsychotics d. ...
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1904 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album '' 63/19'' by Kool A.D. * '' Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album ''Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slip ...
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Polish Chemists
Polish may refer to: * Anything from or related to Poland, a country in Europe * Polish language * Poles, people from Poland or of Polish descent * Polish chicken * Polish brothers (Mark Polish and Michael Polish, born 1970), American twin screenwriters Polish may refer to: * Polishing, the process of creating a smooth and shiny surface by rubbing or chemical action ** French polishing, polishing wood to a high gloss finish * Nail polish * Shoe polish * Polish (screenwriting), improving a script in smaller ways than in a rewrite See also * * * Polonaise (other) A polonaise ()) is a stately dance of Polish origin or a piece of music for this dance. Polonaise may also refer to: * Polonaises (Chopin), compositions by Frédéric Chopin ** Polonaise in A-flat major, Op. 53 (french: Polonaise héroïque, ... {{Disambiguation, surname Language and nationality disambiguation pages ...
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Urea
Urea, also known as carbamide, is an organic compound with chemical formula . This amide has two amino groups (–) joined by a carbonyl functional group (–C(=O)–). It is thus the simplest amide of carbamic acid. Urea serves an important role in the metabolism of nitrogen-containing compounds by animals and is the main nitrogen-containing substance in the urine of mammals. It is a colorless, odorless solid, highly soluble in water, and practically non-toxic ( is 15 g/kg for rats). Dissolved in water, it is neither acidic nor alkaline. The body uses it in many processes, most notably nitrogen excretion. The liver forms it by combining two ammonia molecules () with a carbon dioxide () molecule in the urea cycle. Urea is widely used in fertilizers as a source of nitrogen (N) and is an important raw material for the chemical industry. In 1828 Friedrich Wöhler discovered that urea can be produced from inorganic starting materials, which was an important conceptual milesto ...
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Theophylline
Theophylline, also known as 1,3-dimethylxanthine, is a phosphodiesterase inhibiting drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. As a member of the xanthine family, it bears structural and pharmacological similarity to theobromine and caffeine, and is readily found in nature, being present in tea (''Camellia sinensis'') and cocoa (''Theobroma cacao''). A small amount of theophylline is one of the products of caffeine metabolic processing in the liver. Medical uses The main actions of theophylline involve: * relaxing bronchial smooth muscle * increasing heart muscle contractility and efficiency (positive inotrope) * increasing heart rate (positive chronotropic) * increasing blood pressure * increasing renal blood flow * anti-inflammatory effects * central nervous system stimulatory effect mainly on the medullary respiratory center. The main therapeutic uses of theophylline are a ...
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Caffeine
Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class. It is mainly used recreationally as a cognitive enhancer, increasing alertness and attentional performance. Caffeine acts by blocking binding of adenosine to the adenosine A1 receptor, which enhances release of the neurotransmitter acetylcholine. Caffeine has a three-dimensional structure similar to that of adenosine, which allows it to bind and block its receptors. Caffeine also increases cyclic AMP levels through nonselective inhibition of phosphodiesterase. Caffeine is a bitter, white crystalline purine, a methylxanthine alkaloid, and is chemically related to the adenine and guanine bases of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). It is found in the seeds, fruits, nuts, or leaves of a number of plants native to Africa, East Asia and South America, and helps to protect them against herbivores and from competition by preventing the germination of nearby seeds, as well as ...
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Total Synthesis
Total synthesis is the complete chemical synthesis of a complex molecule, often a natural product, from simple, commercially-available precursors. It usually refers to a process not involving the aid of biological processes, which distinguishes it from semisynthesis. Syntheses may sometimes conclude at a precursor with further known synthetic pathways to a target molecule, in which case it is known as a formal synthesis. Total synthesis target molecules can be natural products, medicinally-important active ingredients, known intermediates, or molecules of theoretical interest. Total synthesis targets can also be organometallic or inorganic, though these are rarely encountered. Total synthesis projects often require a wide diversity of reactions and reagents, and subsequently requires broad chemical knowledge and training to be successful. Often, the aim is to discover a new route of synthesis for a target molecule for which there already exist known routes. Sometimes, however, no ...
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Proxibarbital
Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956. It has anti-anxiety properties and is, in contrast to most barbiturates, almost without hypnotic action. It was also used in the treatment of migraine headaches in a similar manner to butalbital Butalbital is a barbiturate with an intermediate duration of action. Butalbital is often combined with other medications, such as paracetamol (acetaminophen) or aspirin, for the treatment of pain and headache. The various formulations combined wi .... Valofane isomerises to Proxibarbal in vivo. References Barbiturates Antimigraine drugs Allyl compounds {{sedative-stub ...
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Barbiturate
Barbiturates are a class of depressant drugs that are chemically derived from barbituric acid. They are effective when used medically as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential as well as overdose potential among other possible adverse effects. They have been used recreationally for their anxiolytic and sedative effects, and are thus controlled in most countries due to the risks associated with such use. Barbiturates have largely been replaced by benzodiazepines and nonbenzodiazepines ("Z-drugs") in routine medical practice, particularly in the treatment of anxiety disorders and insomnia, because of the significantly lower risk of overdose, and the lack of an antidote for barbiturate overdose. Despite this, barbiturates are still in use for various purposes: in general anesthesia, epilepsy, treatment of acute migraines or cluster headaches, acute tension headaches, euthanasia, capital punishment, and assiste ...
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Wrocław
Wrocław (; , . german: Breslau, , also known by other names) is a city in southwestern Poland and the largest city in the historical region of Silesia. It lies on the banks of the Oder in the Silesian Lowlands of Central Europe, roughly from the Sudeten Mountains to the south. , the official population of Wrocław is 674,132 making it the third largest city in Poland. The population of the Wrocław metropolitan area is around 1.25 million. Wrocław is the historical capital of Silesia and Lower Silesia. Today, it is the capital of the Lower Silesian Voivodeship. The history of the city dates back over 1,000 years; at various times, it has been part of the Kingdom of Poland, the Kingdom of Bohemia, the Kingdom of Hungary, the Habsburg monarchy of Austria, the Kingdom of Prussia and Germany, until it became again part of Poland in 1945 as the result of territorial changes of Poland immediately after World War II. Wrocław is a university city with a student popula ...
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Nowy Sącz
Nowy Sącz (; hu, Újszandec; yi, Tzanz, צאַנז; sk, Nový Sonč; german: Neu-Sandez) is a city in the Lesser Poland Voivodeship of southern Poland. It is the district capital of Nowy Sącz County as a separate administrative unit. It has a population of around 83,116 as of 2021. Names Nowy Sącz has been known in German as ''Neu Sandez'' and in Hungarian as ''Újszandec''. The Rusyn name was Novyj Sanc. Its Yiddish names include צאַנז (''Tsanz'') and נײַ-סאַנץ (''Nay-Sants''). Geography Nowy Sącz is located at the confluence of the Kamienica River and Dunajec, about north of the Slovak border, in the Sądecka Valley (''Kotlina Sądecka'') at an altitude of . It is surrounded by ranges of the eastern Outer Western Carpathian Mountains: Beskid Sądecki to the south, Beskid Wyspowy to the west, Beskid Niski to the southeast, and the foothills of Pogórze Rożnowskie to the north. The geological basis is Carpathian flysch – an undifferentiat ...
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