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Biological Computing
Biological computers use biologically derived molecules — such as DNA and/or proteins — to perform digital or real computations. The development of biocomputers has been made possible by the expanding new science of nanobiotechnology. The term nanobiotechnology can be defined in multiple ways; in a more general sense, nanobiotechnology can be defined as any type of technology that uses both nano-scale materials (i.e. materials having characteristic dimensions of 1-100 nanometers) and biologically based materials. A more restrictive definition views nanobiotechnology more specifically as the design and engineering of proteins that can then be assembled into larger, functional structures The implementation of nanobiotechnology, as defined in this narrower sense, provides scientists with the ability to engineer biomolecular systems specifically so that they interact in a fashion that can ultimately result in the computational functionality of a computer. Scientific background B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proteins
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computational Genes
A computational gene is a molecular automaton consisting of a structural part and a functional part; and its design is such that it might work in a cellular environment. The structural part is a naturally occurring gene, which is used as a skeleton to encode the input and the transitions of the automaton (Fig. 1A). The conserved features of a structural gene (e.g., DNA polymerase binding site, start and stop codons, and splicing sites) serve as constants of the computational gene, while the coding regions, the number of exons and introns, the position of start and stop codon, and the automata theoretical variables (symbols, states, and transitions) are the design parameters of the computational gene. The constants and the design parameters are linked by several logical and biochemical constraints (e.g., encoded automata theoretic variables must not be recognized as splicing junctions). The input of the automaton are molecular markers given by single stranded DNA (ssDNA) molecules. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Data Storage Device
Data ( , ) are a collection of discrete or continuous values that convey information, describing the quantity, quality, fact, statistics, other basic units of meaning, or simply sequences of symbols that may be further interpreted formally. A datum is an individual value in a collection of data. Data are usually organized into structures such as tables that provide additional context and meaning, and may themselves be used as data in larger structures. Data may be used as variables in a computational process. Data may represent abstract ideas or concrete measurements. Data are commonly used in scientific research, economics, and virtually every other form of human organizational activity. Examples of data sets include price indices (such as the consumer price index), unemployment rates, literacy rates, and census data. In this context, data represent the raw facts and figures from which useful information can be extracted. Data are collected using techniques ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcriptor
A transcriptor is a transistor-like device composed of DNA and RNA rather than a semiconducting material such as silicon. Prior to its invention in 2013, the transcriptor was considered an important component to build biological computers. Background To function, a modern computer needs three different capabilities: It must be able to store information, transmit information between components, and possess a basic system of logic. Prior to March 2013, scientists had successfully demonstrated the ability to store and transmit data using biological components made of proteins and DNA. Simple two-terminal logic gates had been demonstrated, but required multiple layers of inputs and thus were impractical due to scaling difficulties. Invention and description On March 28, 2013, a team of bioengineers from Stanford University led by Drew Endy announced that they had created the biological equivalent of a transistor, which they named a "transcriptor". That is, they created a thre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transistor
A transistor is a semiconductor device used to Electronic amplifier, amplify or electronic switch, switch electrical signals and electric power, power. It is one of the basic building blocks of modern electronics. It is composed of semiconductor material, usually with at least three terminal (electronics), terminals for connection to an electronic circuit. A voltage or Electric current, current applied to one pair of the transistor's terminals controls the current through another pair of terminals. Because the controlled (output) power can be higher than the controlling (input) power, a transistor can amplify a signal. Some transistors are packaged individually, but many more in miniature form are found embedded in integrated circuits. Because transistors are the key active components in practically all modern electronics, many people consider them one of the 20th century's greatest inventions. Physicist Julius Edgar Lilienfeld proposed the concept of a field-effect transisto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drew Endy
Andrew (Drew) David Endy (born 1970) is a synthetic biologist and tenured associate professor of bioengineering at Stanford University, California. Education Endy received his PhD from Dartmouth College in 1997 for his work on genetic engineering using T7 phage. Career Endy was a junior fellow for three years and later an Assistant Professor of Biological Engineering at the Massachusetts Institute of Technology (2002–2008). In 2008, Endy moved to Stanford University, where he currently serves as an Associate Professor of Bioengineering. Research With Thomas Knight, Gerald Jay Sussman, Randy Rettberg, and others at MIT, Endy worked on synthetic biology and the engineering of standardized biological components, devices, and parts, collectively known as BioBricks.From the cells up '' |
Stanford University
Leland Stanford Junior University, commonly referred to as Stanford University, is a Private university, private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth List of governors of California, governor of and then-incumbent List of United States senators from California, United States senator representing California) and his wife, Jane Stanford, Jane, in memory of their only child, Leland Stanford Jr., Leland Jr. The university admitted its first students in 1891, opening as a Mixed-sex education, coeducational and non-denominational institution. It struggled financially after Leland died in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, university Provost (education), provost Frederick Terman inspired an entrepreneurship, entrepreneurial culture to build a self-sufficient local industry (later Silicon Valley). In 1951, Stanfor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Binary Numeral System
A binary number is a number expressed in the base-2 numeral system or binary numeral system, a method for representing numbers that uses only two symbols for the natural numbers: typically "0" ( zero) and "1" ( one). A ''binary number'' may also refer to a rational number that has a finite representation in the binary numeral system, that is, the quotient of an integer by a power of two. The base-2 numeral system is a positional notation with a radix of 2. Each digit is referred to as a bit, or binary digit. Because of its straightforward implementation in digital electronic circuitry using logic gates, the binary system is used by almost all modern computers and computer-based devices, as a preferred system of use, over various other human techniques of communication, because of the simplicity of the language and the noise immunity in physical implementation. History The modern binary number system was studied in Europe in the 16th and 17th centuries by Thomas Harrio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tom Knight (scientist)
Tom Knight is an American synthetic biologist and computer engineer, who was formerly a senior research scientist at the MIT Computer Science and Artificial Intelligence Laboratory, a part of the MIT School of Engineering. He now works at the synthetic biology company Ginkgo Bioworks, which he cofounded in 2008. Career Work in electrical engineering and computer science Tom Knight arrived at MIT when he was fourteen. Even though he only started his undergraduate studies at the regular age of 18, he took classes in computer programming and organic chemistry during high school because he lived close to the university. He built early hardware such as ARPANET interfaces for host #6 on the network, some of the first bitmapped displays, the ITS time sharing system, Lisp machines (he was also instrumental in releasing a version of the operating system for the Lisp machine under a BSD license), the Connection Machine, and parallel symbolic processing computer systems. In 1967 Kn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Logic
Logic is the study of correct reasoning. It includes both formal and informal logic. Formal logic is the study of deductively valid inferences or logical truths. It examines how conclusions follow from premises based on the structure of arguments alone, independent of their topic and content. Informal logic is associated with informal fallacies, critical thinking, and argumentation theory. Informal logic examines arguments expressed in natural language whereas formal logic uses formal language. When used as a countable noun, the term "a logic" refers to a specific logical formal system that articulates a proof system. Logic plays a central role in many fields, such as philosophy, mathematics, computer science, and linguistics. Logic studies arguments, which consist of a set of premises that leads to a conclusion. An example is the argument from the premises "it's Sunday" and "if it's Sunday then I don't have to work" leading to the conclusion "I don't have to wor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Economical
An economic system, or economic order, is a system of production, resource allocation and distribution of goods and services within an economy. It includes the combination of the various institutions, agencies, entities, decision-making processes, and patterns of consumption that comprise the economic structure of a given community. An economic system is a type of social system. The mode of production is a related concept. All economic systems must confront and solve the four fundamental economic problems: * What kinds and quantities of goods shall be produced: This fundamental economic problem is anchored on the theory of pricing. The theory of pricing, in this context, has to do with the economic decision-making between the production of capital goods and consumer goods in the economy in the face of scarce resources. In this regard, the critical evaluation of the needs of the society based on population distribution in terms of age, sex, occupation, and geography is very pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
