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Biohub
Chan Zuckerberg Biohub (CZ Biohub), or simply Biohub, is a nonprofit research organization. In addition to supporting and conducting original research, CZ Biohub acts as a hub and fosters science collaboration between UC Berkeley, UC San Francisco (UCSF) and Leland Stanford Jr University, Stanford. The Biohub is funded by a $600 million contribution from Meta (company), Meta CEO and founder Mark Zuckerberg and his wife Priscilla Chan (philanthropist), Priscilla Chan. It was co-led by Stephen Quake and Joseph DeRisi from its inception in 2016 until 2022, when Quake left to become president of the Biohub Network. Sandra Schmid joined as Chief Scientific Officer in 2020. History The idea for CZ Biohub originated in 2015 when DeRisi and Quake, along with Chan and Zuckerberg, agreed on the need for a collaborative alliance of Stanford University, UC San Francisco and UC Berkeley devoted to fundamental biomedical research. The organization was established in 2016, funded by a $600 mill ...
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Chan Zuckerberg Initiative
The Chan Zuckerberg Initiative (CZI) is an organization established and owned by Facebook founder Mark Zuckerberg and his wife Priscilla Chan with an investment of 99 percent of the couple's wealth from their Facebook shares over their lifetime. The CZI is legally set up as a limited liability company (LLC) that can be seen as a for-profit charity and is an example of philanthrocapitalism. CZI has been deemed likely to be "one of the most well-funded philanthropies in human history". Chan and Zuckerberg announced its creation on 1 December 2015, to coincide with the birth of their first child. Chan has said that her background as a child of immigrant refugees and experience as a teacher and pediatrician for vulnerable children influences how she approaches the philanthropy's work in science, education, immigration reform, housing, criminal justice, and other local issues. The Chan Zuckerberg Initiative's main areas of work include science, education, and justice and opportuni ...
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Mark Zuckerberg
Mark Elliot Zuckerberg (; born May 14, 1984) is an American businessman who co-founded the social media service Facebook and its parent company Meta Platforms, of which he is the chairman, chief executive officer, and controlling shareholder. Zuckerberg has been the subject of multiple lawsuits regarding the creation and ownership of the website as well as issues such as user privacy. Born in White Plains, New York, Zuckerberg briefly attended Harvard College, where he launched Facebook in February 2004 with his roommates Eduardo Saverin, Andrew McCollum, Dustin Moskovitz and Chris Hughes. Zuckerberg took the Initial public offering of Facebook, company public in May 2012 with majority shares. He became the world's youngest self-made billionaire in 2008, at age 23, and has consistently ranked among the The World's Billionaires, world's wealthiest individuals. According to ''Forbes'', Zuckerberg's estimated net worth stood at US$221.2 billion as of May 2025, making him the s ...
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Joseph DeRisi
Joseph Lyman DeRisi is an American biochemist, specializing in molecular biology, parasitology, genomics, virology, and computational biology. Early life and education DeRisi was raised in Carmichael, California, where he graduated from Del Campo High School. He received a B.A. in biochemistry and molecular biology in 1992 from the University of California, Santa Cruz. DeRisi earned his Ph.D. in biochemistry from Stanford University in 1999. Working in the laboratory of Patrick O. Brown, he developed methods for the production and use of DNA microarrays in molecular biology, and his thesis was a genome-wide expression analysis of the budding yeast ''S. cerevisiae''. Upon graduation, DeRisi accepted a position as a Sandler Fellow at the University of California San Francisco. Career and research DeRisi has been a faculty member of the UCSF biochemistry and biophysics department since 1999. As of 2022 he is a professor of biochemistry and biophysics and is also the director of UCSF ...
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UC San Francisco
The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California, United States. It is part of the University of California system and is dedicated entirely to health science and life science. It conducts research and teaching in medical and biological sciences. UCSF was founded as Toland Medical College in 1864. In 1873, it became affiliated with the University of California as its Medical Department. In the same year, it incorporated the California College of Pharmacy and in 1881 it established a dentistry school. Its facilities were located in both Berkeley and San Francisco. In 1964, the school gained full administrative independence as a campus of the UC system, headed by its own chancellor, and in 1970 it gained its current name. Historically based at Parnassus Heights with satellite facilities throughout the city, UCSF developed a second major campus in the newly redeveloped Mission Bay district in the early 20 ...
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Leland Stanford Jr University
Leland Stanford Junior University, commonly referred to as Stanford University, is a private research university in Stanford, California, United States. It was founded in 1885 by railroad magnate Leland Stanford (the eighth governor of and then-incumbent United States senator representing California) and his wife, Jane, in memory of their only child, Leland Jr. The university admitted its first students in 1891, opening as a coeducational and non-denominational institution. It struggled financially after Leland died in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, university provost Frederick Terman inspired an entrepreneurial culture to build a self-sufficient local industry (later Silicon Valley). In 1951, Stanford Research Park was established in Palo Alto as the world's first university research park. By 2021, the university had 2,288 tenure-line faculty, senior fellows, center fellows, and medical fa ...
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Chief Operating Officer
A chief operating officer (COO), also called chief operations officer, is an executive in charge of the daily operations of an organization (i.e. personnel, resources, and logistics). COOs are usually second-in-command immediately after the CEO, and report directly to them, acting on their behalf in their absence. In some situations, for example where a COO is appointed as the CEO's successor, the position may be appointed by the board of directors. Responsibilities and similar titles Unlike other C-suite positions, which tend to be defined according to commonly designated responsibilities across most companies, a COO's job tends to be defined in relation to the specific CEO with whom they work, given the close working relationship of these two individuals. The selection of a COO is similar in many ways to the selection of a vice president or chief of staff of the United States: power and responsibility structures vary in government and private regimes depending on the sty ...
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BioRxiv
bioRxiv (pronounced "bio-archive") is an open access preprint repository for the biological sciences co-founded by John Inglis and Richard Sever in November 2013. It was hosted by Cold Spring Harbor Laboratory (CSHL) until March 11, 2025, when ownership transferred to the newly formed non-profit openRxiv, dedicated to bioRxiv and medRxiv. As preprints, papers hosted on bioRxiv are not peer-reviewed (though submissions may be undergoing peer review and peer reviews from other sources may be posted alongside preprints). However, all submissions undergo a basic scrutinization process, which includes safeguarding checks, an automated plagiarism screening and an assessment of appropriateness. Moreover, readers may post comments. It has been measured that two thirds of the papers posted in bioRxiv are later published in peer-reviewed journals. BioRxiv, and its sister site, medRxiv, have been major sources for the dissemination of COVID-19 research. History BioRxiv was inspired ...
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Preprint
In academic publishing, a preprint is a version of a scholarly or scientific paper that precedes formal peer review and publication in a peer-reviewed scholarly or scientific journal. The preprint may be available, often as a non-typeset version available for free, before or after a paper is published in a journal. History Since 1991, preprints have increasingly been distributed electronically on the Internet, rather than as paper copies. This has given rise to massive preprint databases such as arXiv and HAL (open archive) etc. to institutional repositories. The sharing of preprints goes back to at least the 1960s, when the National Institutes of Health circulated biological preprints. After six years the use of these Information Exchange Groups was stopped, partially because journals stopped accepting submissions shared via these channels. In 2017, the Medical Research Council started supporting citations of preprints in grant and fellowship applications, and Wellcome Tru ...
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Single Cell Sequencing
Single-cell sequencing examines the nucleic acid Genome sequence, sequence information from individual Cell (biology), cells with optimized next generation sequencing, next-generation sequencing technologies, providing a higher resolution of cellular differences and a better understanding of the function of an individual cell in the context of its microenvironment. For example, in cancer, sequencing the DNA of individual cells can give information about mutations carried by small populations of cells. In development, sequencing the RNAs expressed by individual cells can give insight into the existence and behavior of different cell types. In microbial systems, a population of the same species can appear genetically clonal. Still, single-cell sequencing of RNA or Epigenetics, epigenetic modifications can reveal cell-to-cell variability that may help populations rapidly adapt to survive in changing environments. Background A typical human cell consists of about 2 x 3.3 billion base ...
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MacArthur Fellows Program
The MacArthur Fellows Program, also known as the MacArthur Fellowship and colloquially called the "Genius Grant", is a prize awarded annually by the MacArthur Foundation, John D. and Catherine T. MacArthur Foundation to typically between 20 and 30 individuals working in any field who have shown "extraordinary originality and dedication in their creative pursuits and a marked capacity for self-direction" and are citizens or residents of the United States. According to the foundation's website, "the fellowship is not a reward for past accomplishments but rather an investment in a person's originality, insight, and potential", but it also says such potential is "based on a track record of significant accomplishments". The current prize is $800,000 paid over five years in quarterly installments. Previously, it was $625,000. This figure was increased from $500,000 in 2013 with the release of a review of the MacArthur Fellows Program. The award has been called "one of the most signifi ...
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Pathogen
In biology, a pathogen (, "suffering", "passion" and , "producer of"), in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a Germ theory of disease, germ. The term ''pathogen'' came into use in the 1880s. Typically, the term ''pathogen'' is used to describe an ''infectious'' microorganism or agent, such as a virus, bacterium, protozoan, prion, viroid, or fungus. Small animals, such as helminths and insects, can also cause or Transmission (medicine), transmit disease. However, these animals are usually referred to as parasites rather than pathogens. The scientific study of microscopic organisms, including microscopic pathogenic organisms, is called microbiology, while parasitology refers to the scientific study of parasites and the organisms that host them. There are several pathways through which pathogens can invade a host. The principal pathways have different episodic time ...
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